NASA Spaceline Current Awareness List #724 18 November 2016 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, November 18, 2016

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here: 



Please note: The next issue of SPACELINE Current Awareness (List #725) will be sent on Monday, November 30, 2016.

 Papers deriving from NASA support:


Jatkar A, Kurland IJ, Judex S.

Diets high in fat or fructose differentially modulate bone health and lipid metabolism.

Calcif Tissue Int. 2016 Nov 10. [Epub ahead of print]

PI: S. Judex

Journal Impact Factor: 3.052

Funding: "Financial support from Stony Brook University School of Medicine TRO FUSION Award (SJ), NIH/NIAMS R01AR052778 (SJ), NASA NNX-12AL25G (SJ), and Einstein-Mount Sinai Diabetes Research Center Grant P60DK020541 (IJK) was greatly appreciated."



La Tessa C, Sivertz M, Chiang IH, Lowenstein D, Rusek A.

Overview of the NASA Space Radiation Laboratory.

Life Sci Space Res. 2016 Nov 11. [Article in Press]

Journal Impact Factor: Not available for this journal

Funding: "The work at NSRL is supported by NASA (Contract No. T570X) and performed under the United State Department of Energy (Contract No. DE-AC02-98CH10886)."



Bell ST, Brown SG, Mitchell TD.

Data mining review of team benchmark studies related to long-duration space exploration missions.

Houston, TX: NASA Johnson Space Center, 2016 Nov. 84 p. NASA/TM-2016-219280.

Note:  From the abstract: "We conducted a quantitative review of existing studies benchmarking team factors in long-duration space exploration missions (LDSEM)-analog environments to summarize the existing quantitative evidence on team functioning in such environments and to identify gaps to address in future research. . . We describe the methodology we used, the results of our efforts, and important research priorities related to Team Gap 1 moving forward." This publication may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: "This work was supported by contract NNJ15HK18P, awarded to the first author from the National Aeronautics and Space Administration (NASA)."



Alvarez AA, Han SW, Toyota M, Brillada C, Zheng J, Gilroy S, Rojas-Pierce M.

Wortmannin-induced vacuole fusion enhances amyloplast dynamics in Arabidopsis zigzag1 hypocotyls.

J Exp Bot. 2016 Nov 5. [Epub ahead of print]

PIs: M. Rojas-Pierce, S. Gilroy

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.914

Funding: "This work was supported by NASA Space Life and Physical Sciences Division (NNX13AM49G to MRP and NNX14AT25G to SG), National Science Foundation (MCB-1244354 to MRP) and JST (PRESTO award to MT)."



Other papers of interest:



Kononikhin AS, Starodubtseva NL, Pastushkova LK, Kashirina DN, Fedorchenko KY, Brhozovsky AG, Popov IA, Larina IM, Nikolaev EN.

Spaceflight induced changes in the human proteome.

Expert Rev Proteomics. 2016 Nov 6. [Epub ahead of print] Review.

Note: Spaceflight, ground-based, and simulated microgravity studies are discussed.



Li H, He Y, Di C, Yan J, Zhang H.

Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice.

Life Sci. 2016 Nov 1. [Epub ahead of print]



Abbasi J.

Do Apollo astronaut deaths shine a light on deep space radiation and cardiovascular disease?

JAMA. 2016 Nov 9. [Epub ahead of print]

Note: This is a "Medical News/Perspectives" article which comments on the article: Delp MD, Charvat JM, Limoli CL, Globus RK, Ghosh P. Apollo lunar astronauts show higher cardiovascular disease mortality: Possible deep space radiation effects on the vascular endothelium. Sci Rep. 2016 Jul 28;6:29901., which appeared in Current Awareness List #709, Aug 5, 2016.  This article may be obtained online without charge.



Lu YM, Jiao B, Lee J, Zhang L, Yu ZB.

Simulated microgravity increases myocardial susceptibility to ischemia-reperfusion injury via a deficiency of AMP-activated protein kinase.

Can J Physiol Pharmacol. 2016 Sep 1:1-13. [Epub ahead of print]

Note: Hindlimb unloading study.



Hirunsai M, Yimlamai T, Suksamrarn A.

Effect of 20-hydroxyecdysone on proteolytic regulation in skeletal muscle atrophy.

In Vivo. 2016 Nov-Dec;30(6):869-77.

Note: Muscle atrophy was induced by Achilles tendon transection.



Sanchez B, Rutkove SB.

Electrical impedance myography and its applications in neuromuscular disorders.

Neurotherapeutics. 2016 Nov 3. [Epub ahead of print] Review.

Note: Hindlimb unloading studies are discussed.



Sandino C, McErlain DD, Schipilow J, Boyd SK.

Mechanical stimuli of trabecular bone in osteoporosis: A numerical simulation by finite element analysis of microarchitecture.

J Mech Behav Biomed Mater. 2016 Oct 15;66:19-27.



Bespalov VG, Alexandrov VA, Semenov AL, Kovan'ko EG, Ivanov SD, Vysochina GI, Kostikova Vcapital A C, Baranenko DA.

The inhibitory effect of meadowsweet (Filipendula ulmaria) on radiation-induced carcinogenesis in rats.

Int J Radiat Biol. 2016 Nov 9:1-29. [Epub ahead of print]



Chen R, Wang YW, Fornace AJ Jr, Li HH.

Impairment of the intrinsic capability of Th1 polarization in irradiated mice: A close look at the imbalanced Th1/Th2 response after irradiation.

Radiat Res. 2016 Nov 16. [Epub ahead of print]



El-Desouky W, Mahmoud AH, Abbas MM.

Radioprotective effect of green tea and grape seed extracts mixture on gamma irradiation induced immune suppression in male albino rats.

Int J Radiat Biol. 2016 Nov 4:1-25. [Epub ahead of print]



Kákona M, Ploc O, Kyselová D, Kubančák J, Langer R, Kudela K.

Investigation on contribution of neutron monitor data to estimation of aviation doses.

Life Sci Space Res. 2016 Nov 16. [Article in Press]



Terradas M, Martín M, Repullès J, Huarte M, Genescà A.

Distinct sets of lncRNAs are differentially modulated after exposure to high and low doses of X rays.

Radiat Res. 2016 Nov 14. [Epub ahead of print]



Suedfeld P, Halliwell JE, Dennis Rank A, Buckley ND.

Psychosocial aspects of spaceflight and aging.

REACH. 2016 Nov 14. [Article in Press] Review.



Bufacchi RJ, Iannetti GD.

Gravitational cues modulate the shape of defensive peripersonal space.

Curr Biol. 2016 Nov 7;26(21):R1133-4.

Note: This article may be obtained online without charge.



Cone BL, Goble DJ, Rhea CK.

Relationship between changes in vestibular sensory reweighting and postural control complexity.

Exp Brain Res. 2016 Nov 3. [Epub ahead of print]



Lim SB, Cleworth TW, Horslen BC, Blouin JS, Inglis JT, Carpenter MG.

Postural threat influences vestibular-evoked muscular responses.

J Neurophysiol. 2016 Nov 9:jn.00712.2016. [Epub ahead of print]


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