SpaceRef

SpaceRef


NASA Spaceline Current Awareness List #734 3 February 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, February 3, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.
 
In case you missed it: Nature News section reported on January 26 about early results from NASA’s Twin Study presented at the Human Research Program Investigators’ Workshop in Galveston, TX. See the article at http://www.nature.com/news/astronaut-twin-study-hints-at-stress-of-space-travel-1.21380.
 
 
Papers deriving from NASA support:
 
1
Sundaresan A, Mehta SK, Schlegel TT, Russomano T, Pierson DL, Mann V, Mansoor E, Olamigoke L, Okoro E.
Placental growth factor levels in populations with high versus low risk for cardiovascular disease and stressful physiological environments such as microgravity: A pilot study.
Microgravity Sci Technol. 2017 Feb 2:1-5. [Article in Press]
http://link.springer.com/article/10.1007/s12217-016-9534-5
Note: From the abstract: "This pilot study compared placental [induced] growth factor (PIGF) levels in populations with high versus low risk for cardiovascular disease. Previous experiments from our laboratory revealed that the angiogenic factor PIGF was up regulated in modeled microgravity conditions in human lymphocytes leading to possible atherogenesis and pathogenesis in microgravity. Since the findings came from microgravity analog experiments, there is a strong link to its usefulness in the microgravity field as a biomarker."
Journal Impact Factor: 0.725
Funding: No funding cited. S.K. Mehta, T.T. Schlegel, and D.L. Pierson are affiliated with NASA Johnson Space Center.
 
2
Kurti SP, Rosenkranz SK, Chapes SK, Teeman CS, Cull BJ, Emerson SR, Levitt MH, Smith JR, Harms CA.
Does chronic physical activity level modify the airway inflammatory response to an acute bout of exercise in the postprandial period?
Appl Physiol Nutr Metab. 2017 Feb;42(2):173-80.
https://www.ncbi.nlm.nih.gov/pubmed/28121185
PI: S.K. Chapes
Journal Impact Factor: 2.339
Funding: "The work was funded by SK Rosenkranz University Small Research Grant (USRG) and SK Chapes laboratory funding from NASA grants NNX13AN34G and NNX15AB45G and NIH grant GM103418."
 
3
Limoli CL.
Deep-space deal breaker.
Sci Am. 2017 Jan 17;316(2):54-9.
https://www.ncbi.nlm.nih.gov/pubmed/28118333
PI: C.L. Limoli
Journal Impact Factor: 1.138
Funding: No funding cited. PI reports that the article covers research that was funded by NASA.
 
4
Choi WG, Miller G, Wallace I, Harper J, Mittler R, Gilroy S.
Orchestrating rapid long-distance signaling in plants with Ca2+, ROS, and electrical signals.
Plant J. 2017 Jan 23. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/28112437
PI: S. Gilroy
Journal Impact Factor: 5.468
Funding: "We gratefully acknowledge the support of the National Science Foundation MCB-1329723, MCB-1613462, IOS-1557899, IOS-1353886, IOS-0639964, IOS-0743954, IOS-1557787, and NASA NNX14AT25G, and the OVPRI research funding (University of Nevada, Reno), and the University of North Texas, College of Arts and Sciences, Grant No. IS-4652-13 R from BARD, The United States - Israel Binational Agricultural Research and Development Fund, and from the Nevada Agricultural Experiment Station (Grant No. NEV00382 and NEV00384), and the Israel Science Foundation (grant no. 938/11)."
______________________________________________________
 
Other papers of interest:
 
1
Dolch ME, Hummel T, Fetter V, Helwig A, Lenic J, Moukhamedieva L, Tsarkow D, Chouker A, Schelling G.
Electronic nose functionality for breath gas analysis during parabolic flight.
Microgravity Sci Technol. 2017 Feb 2:1-7. [Article in Press]
http://link.springer.com/article/10.1007/s12217-017-9536-y
Note: Parabolic flight results.
 
2
Grau M, Abeln V, Vogt T, Bloch W, Schneider S.
Erythrocyte deformability and aggregation responses to intermittent and continuous artificial gravity exposure.
Life Sci Space Res. 2017 Feb 1. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552416301092
Note: A short-arm centrifuge was used.
 
3
Li C, Wang Y, Shi F, Gao Y, Xiqing S.
Effects of clinostat weightlessness simulation on expression of LC3, p62, p53 and p-p70S6K in human umbilical vein endothelial cells.
Space Med Med Eng. 2016;2016(5):313-7. Chinese.
http://caod.oriprobe.com/articles/50249947/Effects_of_Clinostat_Weightlessness_Simulation_on_Expression_of_LC3__p.htm
Note: Rotation was used.
 
4
Howle LE, Weber PW, Nichols JM.
Bayesian approach to decompression sickness model parameter estimation.
Comput Biol Med. 2017 Jan 17;82:3-11. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28119191
 
5
Zhang K, Jiang Z, Ning X, Yu X, Xu J, Buzzacott P, Xu W.
Endothelia-targeting protection by escin in decompression sickness rats.
Sci Rep. 2017 Jan 23;7:41288.
https://www.ncbi.nlm.nih.gov/pubmed/28112272
Note: This article may be obtained online without charge.
 
6
Watanabe N, Hotta H.
Heart rate changes in response to mechanical pressure stimulation of skeletal muscles are mediated by cardiac sympathetic nerve activity.
Front Neurosci. 2016 Jan 10;10:614.
https://www.ncbi.nlm.nih.gov/pubmed/28119562
Note: This article may be obtained online without charge.
 
7
Hirayama Y, Nakanishi R, Tategaki A, Maeshige N, Kondo H, Ishihara A, Roy RR, Fujino H.
Enterococcus faecium strain R30 increases red blood cell velocity and prevents capillary regression in the soleus of hindlimb unloaded rats via the eNOS/VEGF pathway.
Microcirculation. 2017 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28116830
Note: Hindlimb unloading study.
 
8
Sonner MJ, Walters MC, Ladle DR.
Analysis of proprioceptive sensory innervation of the mouse soleus: A whole-mount muscle approach.
PLoS One. 2017 Jan 25;12(1):e0170751.
https://www.ncbi.nlm.nih.gov/pubmed/28122055
Note: This article may be obtained online without charge.
 
9
Jin YR, Stohn JP, Wang Q, Nagano K, Baron R, Bouxsein ML, Rosen CJ, Adarichev VA, Lindner V.
Inhibition of osteoclast differentiation and collagen antibody-induced arthritis by CTHRC1.
Bone. 2017 Jan 21;97:153-67. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28115279
 
10
Ryser MD, Murgas KA.
Bone remodeling as a spatial evolutionary game.
J Theor Biol. 2017 Jan 18;481:16-26.
https://www.ncbi.nlm.nih.gov/pubmed/28108306
 
11
Townsend R, Elliott-Sale KJ, Currell K, Tang J, Fraser WD, Sale C.
The effect of postexercise carbohydrate and protein ingestion on bone metabolism.
Med Sci Sports Exerc. 2017 Jan 24. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28121797
 
12
Cucinotta FA, To K, Cacao E.
Predictions of space radiation fatality risk for exploration missions.
Life Sci Space Res. 2017 Feb 1. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552416301134
Note: This article may be obtained online without charge.
 
13
Hoel DG, Carnes BA.
Cardiovascular effects of fission neutron or 60Co γ exposure in the B6CF1 mouse.
Int J Radiat Biol. 2017 Jan 23:1-21. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28112567
 
14
Hu S, Gao Y, Zhou H, Kong F, Xiao F, Zhou P, Chen Y.
New insight into mitochondrial changes in vascular endothelial cells irradiated by gamma ray.
Int J Radiat Biol. 2017 Jan 23:1-19. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28110593
 
15
Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A.
A new system for three-dimensional clinostat synchronized x-irradiation with a high-speed shutter for space radiation research.
Biol Sci Space. 2016;30:8-16. Epub 2017 Jan 31.
https://www.jstage.jst.go.jp/article/bss/30/0/30_8/_article
Note: This article may be obtained online without charge.
 
16
Islam MT.
Radiation interactions with biological system.
Int J Radiat Biol. 2017 Jan 24:1-28. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28117624
 
17
Lieberman HB, Panigrahi SK, Hopkins KM, Wang L, Broustas CG.
p53 and RAD9, the DNA damage response, and regulation of transcription networks.
Radiat Res. 2017 Jan 31. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28140789
 
18
Welch D, Turner L, Speiser M, Randers-Pehrson G, Brenner DJ.
Scattered dose calculations and measurements in a life-like mouse phantom.
Radiat Res. 2017 Jan 31. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28140787
 
19
Kamal KY, van Loon JJWA, Medina FJ, Herranz R.
Embedding Arabidopsis plant cell suspensions in low-melting agarose facilitates altered gravity studies.
Microgravity Sci Technol. 2017 Jan 31:1-5. [Article in Press]
http://link.springer.com/article/10.1007%2Fs12217-016-9531-8
 
20
Zhang X, Chen L, Zhan H.
Progress of experimental studies on Chinese herbal medicine against physiological disorders induced by weightlessness during space flight.
Space Med Med Eng. 2016;2016(5):376-80. Review. Chinese.
http://caod.oriprobe.com/articles/50249936/Progress_of_Experimental_Studies_on_Chinese_Herbal_Medicine_Against_Ph.htm
Note: Specific space flights are not mentioned in the English abstract.
 

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.