SpaceRef

SpaceRef


NASA Spaceline Current Awareness List #737 24 February 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, February 24, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.
 
In Case You Missed It: Here is a link to a discussion about plants in space from NPR’s Science Friday broadcast on February 3, 2017 – http://www.sciencefriday.com/segments/how-spaceflight-alters-the-eyes/. In this episode, Lauren Silverman of KERA News in Dallas joined host Ira Flatow to discuss the effects of spaceflight on vision and intracranial pressure. The segment also includes part of an interview with Dr. Benjamin Levine about his work on intracranial pressure during spaceflight. The results of the study were published in the paper: Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Jan 16. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/28092926. It appeared in SPACELINE Current Awareness List #733 on 27 January 2017.
 
Papers deriving from NASA support:
 
1
Jafri MA, Al-Qahtani MH, Shay JW.
Role of miRNAs in human cancer metastasis: Implications for therapeutic intervention.
Semin Cancer Biol. 2017 Feb 8. [Epub ahead of print] Review.
https://www.ncbi.nlm.nih.gov/pubmed/28188828
PIs: J.W. Shay; A.J. Fornace Jr/J.W. Shay/NSCOR
Journal Impact Factor: 9.955
Funding: "This work was supported in part by the National Aeronautics and Space Administration NNX16AE08G and NNX15A121G; the National Cancer Institute (Lung SPORE P50CA70907); and the distinguished Southland Financial Corporation Chair in Geriatrics Research to JWS."
 
2
Kramer LA, Hasan KM, Sargsyan AE, Marshall-Goebel K, Rittweger J, Donoviel D, Higashi S, Mwangi B, Gerlach DA, Bershad EM.
Quantitative MRI volumetry, diffusivity, cerebrovascular flow and cranial hydrodynamics during head down tilt and hypercapnia: The SPACECOT study.
J Appl Physiol (1985). 2017 Feb 16:jap.00887.2016. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28209740
PI: E.M. Bershad
Note: Bed rest study.
Journal Impact Factor: 3.004
Funding: "This study was funded by a grant from the National Space Biomedical Research Institute via NASA NCC9-58 and Center for Space Medicine, Baylor College of Medicine. The DLR contribution to this study was funded by DLR-internal cost object 2475 115."
 
3
Simon JC, Wang YN, Cunitz BW, Thiel J, Starr F, Liu Z, Bailey MR.
Effect of carbon dioxide on the twinkling artifact in ultrasound imaging of kidney stones: A pilot study.
Ultrasound Med Biol. 2017 Feb 09. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28190622
PIs: J.C. Simon, M.R. Bailey
Journal Impact Study: 2.298
Funding: "This work was supported by the National Space Biomedical Research Institute through NASA NCC 9-58 (Grants Simon PF03505 and Bailey SMST03402), and the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health (Grants DK043881 and DK092197)."
 
4
Shuryak I, Fornace AJ Jr, Datta K, Suman S, Kumar S, Sachs RK, Brenner DJ.
Scaling human cancer risks from low LET to high LET when dose-effect relationships are complex.
Radiat Res. 2017 Feb 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28218889
PIs: D.J. Brenner; A.J. Fornace Jr/K. Datta/D.J. Brenner/NSCOR
Journal Impact Factor: 3.022
Funding: "This study was supported NASA Grants NNX15AI21G and NNX16AR81A."
 
5
Graham T, Wheeler R.
Mechanical stimulation modifies canopy architecture and improves volume utilization efficiency in bell pepper: Implications for bioregenerative life-support and vertical farming.
Open Agriculture. 2017 Feb;2(1):42.
https://www.degruyter.com/view/j/opag.2017.2.issue-1/opag-2017-0004/opag-2017-0004.xml
PI: R.M. Wheeler
Note: This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: "Oak Ridge Associated Universities (ORAU) NASA Post-Doctoral Research Fellowship Program for financial support of Thomas Graham." The PI reports funding under the Dwarf Fruit Production Study.
 
6
Park J, Salmi ML, Wan Salim WW, Rademacher A, Wickizer B, Schooley A, Benton J, Cantero A, Argote PF, Ren M, Zhang M, Porterfield DM, Ricco AJ, Roux SJ, Rickus JL.
An autonomous lab on a chip for space flight calibration of gravity-induced transcellular calcium polarization in single-cell fern spores.
Lab Chip. 2017 Feb 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28205656
PIs: D.M. Porterfield, S.J. Roux, J. Rickus
Note: The SporeSat bioCD was used as the rotation device.
Journal Impact Factor: 2.628
Funding: "This work was funded by National Aeronautics and Space Administration, grant numbers NNX15AB86A, NNX11AF48A, and NNX15AB85A."
 
7
Frank JD, McGuire K, Moses HR, Stephenson J.
Developing decision aids to enable human spaceflight autonomy.
AI Magazine. 2016 Win;37(4):46-54.
http://www.aaai.org/ojs/index.php/aimagazine/article/view/2683
Note: >From the abstract: "We describe how this new technology changes the way astronauts coordinate with Mission Control Center (MCC), and how the lessons learned from these early demonstrations will enable the operational autonomy needed to ensure astronauts can safely journey to Mars, and beyond."
Journal Impact Factor: 0.628
Funding: "This work was funded by the NASA Advanced Exploration Systems (AES) program."
______________________________________________________
 
Other papers of interest:
 
1
Pietsch J, Gass S, Nebuloni S, Echegoyen D, Riwaldt S, Baake C, Bauer J, Corydon TJ, Egli M, Infanger M, Grimm D.
Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - The SPHEROIDS project.
Biomaterials. 2017 Apr;124:126-56. Epub 2017 Feb 7.
https://www.ncbi.nlm.nih.gov/pubmed/28199884
Note: ISS results.
 
2
Liu H, He J, Li J, Wang F, Zhang P, Li W, Wan Y, Li Y, Tan Y, Chen X.
[Effects on skeletal muscle C2C12 myoblasts during the Shenzhou-10 mission].
Space Med Med Eng. 2016 (2016):391-5. Chinese.
http://caod.oriprobe.com/articles/50462948/_shen_zhou_10_hao__kong_jian_fei_xing_dui_gu_zuo_j.htm
Note: Shenzhou-10 results.
 
3
Pletser V, Frischauf N, Cohen D, Foster M, Spannagel R, Szeszko A, Laufer R.
First Middle East aircraft parabolic flights for ISU participant experiments.
Microgravity Sci Technol. 2017 Feb 16:1-11. [Article in Press]
http://link.springer.com/article/10.1007%2Fs12217-017-9539-8
Note: Parabolic flight results. The flights were conducted as part of the Space Studies Program 2016 of the International Space University summer session at the Technion - Israel Institute of Technology, Haifa, Israel.
 
4
Morita H, Yamaguchi A, Shiba D, Shirakawa M, Takahashi S.
Impact of a simulated gravity load for atmospheric reentry, 10 g for 2 min, on conscious mice.
J Physiol Sci. 2017 Feb 09. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28185235
Note: Centrifugation was used.
 
5
Qui J, Chen Y, Tang H, Yan W, Jianchang W, Yand C.
[Experiments on rats show glutamine helps intestinal tissues recover from positive acceleration].
Space Med Med Eng. 2016 (2016):413-7. Chinese.
http://caod.oriprobe.com/articles/50462949/gu_an_zuo_an_dui_zheng_jia_su_du_bao_lu_hou_da_shu.htm
Note: The method of acceleration is not identified in the abstract.
 
6
Yu L, Fan X, Zhao X, Song X.
[Impact of succinylcholine on soleus muscle discharge in vitro].
Space Med Med Eng. 2016;2016(6):408-12. Chinese.
http://caod.oriprobe.com/articles/50462946/lv_hua_zuo_zuo_dan_jian_dui_da_shu_bi_mu_yu_ji_li_.htm
 
7
Van Scoy GK, George EL, Opoku Asantewaa F, Kerns L, Saunders MM, Prieto-Langarica A.
A cellular automata model of bone formation.
Math Biosci. 2017 Feb 09;286:58-64. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28189632
 
8
Zhang T, Lin S, Shao X, Zhang Q, Xue C, Zhang S, Lin Y, Zhu B, Cai X.
Effect of matrix stiffness on osteoblast functionalization.
Cell Prolif. 2017 Feb 15. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28205330
 
9
Diao Y, Wei L, Wand R, Wang Z.
[Pine cone extract protective effects on osteoblasts at zero gravity].
Space Med Med Eng. 2016 (2016):396-402. Chinese.
http://caod.oriprobe.com/articles/50462947/hong_song_qiu_guo_ti_qu_wu_dui_mo_ni_shi_zhong_you.htm
Note: The method of weightless simulation is not identified in the abstract.
 
10
Miller DM, DeMayo WM, Bourdages GH, Wittman SR, Yates BJ, McCall AA.
Neurons in the pontomedullary reticular formation receive converging inputs from the hindlimb and labyrinth.
Exp Brain Res. 2017 Feb 10. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28188328
 
11
Brandt A, Meeßen J, Jänicke RU, Raguse M, Ott S.
Simulated space radiation: Impact of four different types of high-dose ionizing radiation on the lichen Xanthoria elegans.
Astrobiology. 2017 Feb;17(2):136-44.
https://www.ncbi.nlm.nih.gov/pubmed/28206821
 
12
Jönsson KI, Wojcik A.
Tolerance to X-rays and heavy ions (Fe, He) in the tardigrade Richtersius coronifer and the bdelloid rotifer Mniobia russeola.
Astrobiology. 2017 Feb;17(2):163-7.
https://www.ncbi.nlm.nih.gov/pubmed/28206820
 
13
Tanaka IB 3rd, Komura J, Tanaka S.
Pathology of serially sacrificed female B6C3F1 mice chronically exposed to very low-dose-rate gamma rays.
Radiat Res. 2017 Feb 20. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28218887
 
14
Schumann F, O'Regan JK.
Sensory augmentation: Integration of an auditory compass signal into human perception of space.
Sci Rep. 2017 Feb 14;7:42197.
https://www.ncbi.nlm.nih.gov/pubmed/28195187
Note: This article may be obtained online without charge.
 
15
Török A, Ferrè ER, Kokkinara E, Csepe V, Swapp D, Haggard P.
Up, down, near, far: An online vestibular contribution to distance judgement.
PLoS One. 2017 Jan 13;12(1):e0169990.
https://www.ncbi.nlm.nih.gov/pubmed/28085939
Note: This article may be obtained online without charge.
 
16
Sun J, Qu W, Dong H.
[Analysis of space food packaging].
Space Med Med Eng. 2016 (2016):451-6. Chinese.
http://caod.oriprobe.com/articles/50462941/hang_tian_shi_pin_bao_zhuang_fa_zhan_xu_qiu_fen_xi.htm
 
17
Valon L, Marin-Llauradó A, Wyatt T, Charras G, Trepat X.
Optogenetic control of cellular forces and mechanotransduction.
Nat Commun. 2017 Feb 10;8:14396.
https://www.ncbi.nlm.nih.gov/pubmed/28186127
Note: This article may be obtained online without charge.
 
18
Lin CJ, Cheng CF, Chen HJ, Wu KY.
Training performance of laparoscopic surgery in two- and three-dimensional displays.
Surg Innov. 2017 Feb 1:1553350617692638. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28190372
Note: The NASA Task Load Index was used.

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.

SpaceRef Newsletter