SpaceRef

SpaceRef


NASA Spaceline Current Awareness List #738 3 March 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, March 3, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.
 
 
Papers deriving from NASA support:
 
1
Sultemeier DR, Choy KR, Schweizer FE, Hoffman LF.
Spaceflight-induced synaptic modifications within hair cells of the mammalian utricle.
J Neurophysiol. 2017 Feb 22:jn.00240.2016. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28228581
PI: L.F. Hoffman
Note: STS-131 results.
Journal Impact Factor: 2.653
Funding: "This work was supported by NASA (grant number NNX09AL57G)."
 
2
Barrila J, Yang J, Crabbé A, Sarker SF, Liu Y, Ott CM, Nelman-Gonzalez MA, Clemett SJ, Nydam SD, Forsyth RJ, Davis RR, Crucian BE, Quiriarte H, Roland KL, Brenneman K, Sams C, Loscher C, Nickerson CA.
Three-dimensional organotypic co-culture model of intestinal epithelial cells and macrophages to study Salmonella enterica colonization patterns.
npj Microgravity. 2017 Feb 28;3(1):10.
http://www.nature.com/articles/s41526-017-0011-2
PI: C.A. Nickerson
Note: The NASA Rotating Wall Vessel bioreactor was used. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: "Funded by NASA grant NNX13AM01G (C.A.N., J.B., and C.M.O.), and NIH R01-AI081759 (C.A.N.)."
 
3
Acharya MM, Baddour AA, Kawashita T, Allen BD, Syage AR, Nguyen TH, Yoon N, Giedzinski E, Yu L, Parihar VK, Baulch JE.
Epigenetic determinants of space radiation-induced cognitive dysfunction.
Sci Rep. 2017 Feb 21;7:42885.
https://www.ncbi.nlm.nih.gov/pubmed/28220892
PIs: J.E. Baulch; C.L. Limoli/M.M. Acharya/V.K. Parihar/J.E. Baulch/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 1.946
Funding: "This work was supported by NASA grants NNX13AK69G and NNX13AK70G (JEB), UC Irvine School of Medicine 19900, UC Irvine Institute for Clinical and Translational Sciences (ICTS) and KL2 Award KL2TR001416 (MMA), and NASA grant NNX15AI22G (JEB, MMA)."
 
4
Bullock B, Murray G, Anderson JL, Cooper-O'Neill T, Gooley JJ, Cain SW, Lockley SW.
Constraint is associated with earlier circadian phase and morningness: Confirmation of relationships between personality and circadian phase using a constant routine protocol.
Pers Individ Dif. 2017 Jan;104:69-74.
https://www.ncbi.nlm.nih.gov/pubmed/28216802
PI: S.W. Lockley
Journal Impact Factor: 1.946
Funding: "This work was supported by grants from the National Institute of Mental Health (R01 MH45130; Czeisler/Lockley), National Center for Complementary and Alternative Medicine (R01 AT002129; Czeisler/Lockley), National Institute of Neurological Disorders and Stroke (R01 NS36590; Brainard), and was performed in the Brigham and Women's Hospital General Clinical Research supported by M01 RR02635 and the Harvard Clinical and Translational Science Center (1 UL1 RR025758), from the National Center for Research Resources. Dr. Gooley was supported by a National Heart, Lung, and Blood Institute fellowship in the program of training in Sleep, Circadian and Respiratory Neurobiology at Brigham and Women's Hospital (T32 HL079010). Dr. Lockley was supported in part by the National Space Biomedical Research Institute through NASA NCC 9-58."
______________________________________________________
 
Other papers of interest:
 
1
Shi F, Wang YC, Hu ZB, Xu HY, Sun J, Gao Y, Li XT, Yang CB, Xie C, Li CF, Zhang S, Zhao JD, Cao XS, Sun XQ.
Simulated microgravity promotes angiogenesis through RhoA-dependent rearrangement of the actin cytoskeleton.
Cell Physiol Biochem. 2017 Jan 20;41(1):227-38. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28214845
Note: A 2-D Rotating Wall Vessel was used. This article may be obtained online without charge.
 
2
Seabra AD, Moraes SA, Batista EJ, Garcia TB, Souza MC, Oliveira KR, Herculano AM.
Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions.
Braz J Med Biol Res. 2017 Feb 20;50(3):e5556.
https://www.ncbi.nlm.nih.gov/pubmed/28225888
Note: This article may be obtained online without charge.
 
3
Tamaki H, Yotani K, Ogita F, Hayao K, Nakagawa K, Sugawara K, Kirimoto H, Onishi H, Kasuga N, Yamamoto N.
Electrical stimulation of denervated rat skeletal muscle ameliorates bone fragility and muscle loss in early-stage disuse musculoskeletal atrophy.
Calcif Tissue Int. 2017 Feb 17. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28213864
 
4
Barreto S, Gonzalez-Vazquez A, Cameron AR, Cavanagh B, Murray DJ, O'Brien FJ.
Identification of the mechanisms by which age alters the mechanosensitivity of mesenchymal stromal cells on substrates of differing stiffness: Implications for osteogenesis and angiogenesis.
Acta Biomater. 2017 Feb 16. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28216301
 
5
Miao C, Zhou L, Tian L, Zhang Y, Zhang W, Yang F, Liu T, Tang S, Liu F.
Osteogenic differentiation capacity of in vitro cultured human skeletal muscle for expedited bone tissue engineering.
Biomed Res Int. 2017;2017:8619385.
https://www.ncbi.nlm.nih.gov/pubmed/28210626
Note: This article may be obtained online without charge.
 
6
Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, Sadreyev R, Wu JY, Sakamoto K, Foretz M, Xavier RJ, Baron R, Bouxsein ML, Gardella TJ, Divieti-Pajevic P, Gray NS, Kronenberg HM.
Corrigendum: SIKs control osteocyte responses to parathyroid hormone.
Nat Commun. 2017 Feb 22;8:14745.
https://www.ncbi.nlm.nih.gov/pubmed/28224982
Note: From the authors: "In this article, there are errors in the labelling of the y axis in Fig. 1b. The labels '50', '100' and '150' should have been '500', '1,000' and '1,500', respectively. The correct version of this figure appears as Fig. 1" [in the text]. The original article appeared in Current Awareness List #728, 16 December 2016, https://www.ncbi.nlm.nih.gov/pubmed/ 27759007.  This article may be obtained online without charge.
 
7
Wang J, Liu J, Pan L, Qi R, Liu P, Zhou W, Cai Y.
Storage of passive motion pattern in hippocampal CA1 region depends on CaMKII/CREB signaling pathway in a motion sickness rodent model.
Sci Rep. 2017 Feb 23;7:43385.
https://www.ncbi.nlm.nih.gov/pubmed/28230177
Note: Rotation was used. This article may be obtained online without charge.
 
8
Shaikh AG, Solomon D.
Effects of sustained otolith-only stimulation on post-rotational nystagmus.
Cerebellum. 2017 Feb 21. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28224454
Note: Rotation was used. This article may be obtained online without charge.
 
9
Wiltshire TJ, Butner JE, Fiore SM.
Problem-solving phase transitions during team collaboration.
Cogn Sci. 2017 Feb 18. [Epub ahead of print]
https://www.ncbi.nlm.nih.gov/pubmed/28213928
 
10
Liang C, Li A, Yu H, Li W, Liang C, Guo S, Zhang R, Chu C.
Melatonin regulates root architecture by modulating auxin response in rice.
Front Plant Sci. 2017 Feb 7;8:134.
https://www.ncbi.nlm.nih.gov/pubmed/28223997
Note: This article may be obtained online without charge.
 
11
Becker I, Strauch SM, Hauslage J, Lebert M.
Long term stability of Oligo (dT) 25 magnetic beads for the expression analysis of Euglena gracilis for long term space projects.
Life Sci Space Res. 2017 Mar 2. [Article in Press]
http://www.sciencedirect.com/science/article/pii/S2214552416301158
 
12
Arora GC.
Aerospace dermatology.
Indian J Dermatol. 2017 Jan-Feb;62(1):79-84.
https://www.ncbi.nlm.nih.gov/pubmed/28216729
Note: From the abstract: "This article discusses the physiological effects of this environment on skin, effect of common dermatoses in aerospace environment, effect of microgravity on skin, and occupational hazards of this industry." This article may be obtained online without charge.

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.

NanoRacks