NASA Spaceline Current Awareness List #748 12 May 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, May 12, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,


In case you missed it: On May 5, 2017, The Washington Post published an article, ‘I wanted to serve’: These deaf men helped NASA understand motion sickness in space” about deaf students from Gallaudet University in Washington, D.C. who participated in motion sickness and equilibrium studies for the Navy. Studies were conducted from 1958-1968 through a joint project between the U.S. Naval School of Aviation Medicine and NASA. The story is available at: The article highlights an exhibit at the Gallaudet University Museum entitled Deaf Difference + Space Survival. The display includes over 150 photographs, film footage, documents, scientific reports, personal letters, and filmed interviews. The exhibit runs through the Fall of 2018. More information is available at:



Papers deriving from NASA support:



Backlund PS, Urbanski HF, Doll MA, Hein DW, Bozinoski M, Mason CE, Coon SL, Klein DC.

Daily rhythm in plasma N-acetyltryptamine.

J Biol Rhythms. 2017 May 1:748730417700458. [Epub ahead of print]                       

PI: C.E. Mason

Journal Impact Factor: 2.824

Funding: "This work was supported by funds from the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health (P.S.B., S.L.C., D.C.K.); by NIH grants AG-036670, AG-029612, and OD-011092 (H.F.U.); and by the Bert L. and N. Kuggie Vallee Foundation, the WorldQuant Foundation, NASA (NNX14AH50G, 15-15Omni2-0063), and the Bill and Melinda Gates Foundation (OPP1151054) (C.E.M. and M.B.)."



Matin AC, Wang JH, Keyhan M, Singh R, Benoit M, Parra MP, Padgen MR, Ricco AJ, Chin M, Friedericks CR, Chinn TN, Cohen A, Henschke MB, Snyder TV, Lera MP, Ross SS, Mayberry CM, Choi S, Wu DT, Tan MX, Boone TD, Beasley CC, Spremo SM. 

Payload hardware and experimental protocol development to enable future testing of the effect of space microgravity on the resistance to gentamicin of uropathogenic Escherichia coli and its σs-deficient mutant. 

Life Sci Space Res. 2017 May 10. [Article in Press]

PI: A.C. Matin

Note: The paper describes the E. coli Antimicrobial Satellite (EcAMSat) payload platform developed for future spaceflight. Low-shear modeled microgravity experiments were conducted in high-aspect-ratio-vessel (HARV) reactors.

Journal Impact Factor: 1.97

Funding: "This research was supported by NASA grant NNX10AM90A to A.M. at Stanford and by NASA's Space Life and Physical Sciences Research Division, Human Exploration and Operations Mission Directorate, at NASA Ames Research Center (ARC)."



Karzova MM, Yuldashev PV, Sapozhnikov OA, Khokhlova VA, Cunitz BW, Kreider W, Bailey MR.

Shock formation and nonlinear saturation effects in the ultrasound field of a diagnostic curvilinear probe.

J Acoust Soc Am. 2017 Apr;141(4):2327.

PI: M.R. Bailey

Journal Impact Factor: 1.572

Funding: "Work was supported by NIH NIBIB EB007643, NIDDK P01 DK43881, Russian Science Foundation 14-12-00974, NSBRI through NASA NCC 9-58, and a stipend of the President of Russia."



Moreno-Villanueva M, Wong M, Lu T, Zhang Y, Wu H.

Interplay of space radiation and microgravity in DNA damage and DNA damage response.

npj Microgravity. 2017 May 10;3(1):14. Review.

PIs: Y. Zhang, H. Wu

Note: The authors review results from Gemini and Shuttle flights as well as simulation studies using rotating wall vessels (RWV), and 2D and 3D clinostats, hindlimb unloading, and bed rest. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported in part by grants from the NASA Space Biology Program and the NASA Human Research Program, and by a German Fellowship Program (MMV)."



Other papers of interest:



Albi E, Krüger M, Hemmersbach R, Lazzarini A, Cataldi S, Codini M, Beccari T, Ambesi-Impiombato FS, Curcio F.

Impact of gravity on thyroid cells.

Int J Mol Sci. 2017 May 4;18(5):972.

Note: ISS, TEXUS, and parabolic flight results. 3D clinostats and random positioning machines (RPM) were used for ground-based experiments. This article may be obtained online without charge.



Romano F, Caramia N, Straumann D, Nalivaiko E, Bertolini G.

Cross-coupling vestibular stimulation: Motion sickness and the vestibulo-sympathetic reflex.

J Neurol. 2017 Apr 28. [Epub ahead of print]    

Note: Rotation was used.



Hoshide R, Jandial R.

The gravity of intracranial pressure shifts in outer space.

World Neurosurg. 2017 Apr 25. [Epub ahead of print]

Note: This article refers to: Lawley JS, Petersen LG, Howden EJ, Sarma S, Cornwell WK, Zhang R, Whitworth LA, Williams MA, Levine BD. Effect of gravity and microgravity on intracranial pressure. J Physiol. 2017 Mar 15;595(6):2115-2127., which appeared in Current Awareness List #733, 27 Jan 2017.



Kawao N, Morita H, Obata K, Tatsumi K, Kaji H.

Role of follistatin in muscle and bone alterations induced by gravity change in mice.

J Cell Physiol. 2017 May 4. [Epub ahead of print]

Note: Rotation was used.



Pigna E, Greco E, Morozzi G, Grottelli S, Rotini A, Minelli A, Fulle S, Adamo S, Mancinelli R, Bellezza I, Moresi V.

Denervation does not induce muscle atrophy through oxidative stress.

Eur J Transl Myol. 2017 Mar 3;27(1):6406.

Note: This article may be obtained online without charge.



Shanb AAE, Youssef EF, Muaidi QI, Alothman AA.

Whole body vibration versus magnetic therapy on bone mineral density in elderly osteoporotic individuals.

J Back Musculoskelet Rehabil. 2017 Apr 14. [Epub ahead of print]



Xu H, Wu F, Zhang H, Yang C, Li K, Wang H, Yang H, Liu Y, Ding B, Tan Y, Yuan M, Li Y, Dai Z.

Actin cytoskeleton mediates BMP2-Smad signaling via calponin 1 in preosteoblast under simulated microgravity.

Biochimie. 2017 Apr 27. [Epub ahead of print]

Note: Hindlimb unloading study.



Dahle TJ, Rykkelid AM, Stokkevåg CH, Mairani A, Görgen A, Edin NJ, Rørvik E, Fjæra LF, Malinen E, Ytre-Hauge KS.

Monte Carlo simulations of a low energy proton beamline for radiobiological experiments.

Acta Oncol. 2017 Jun;56(6):779-86.



Zahabi M, Zhang W, Pankok C, Lau MY, Shirley J, Kaber D.

Effect of physical workload and modality of information presentation on pattern recognition and navigation task performance by high-fit young males.

Ergonomics. 2017 Apr 28:1-12. [Epub ahead of print]



Fushiki H, Maruyama M, Shojaku H.

Adaptation of the vertical vestibulo-ocular reflex in cats during low-frequency vertical rotation.

Auris Nasus Larynx. 2017 Apr 27. [Epub ahead of print]

Note: Rotation was used.



Chokroverty S.

Sleep in extreme environment.

In: Sleep disorders medicine. New York: Springer, 2017. p. 1233-41.



Rahman SA, St Hilaire MA, Lockley SW.

The effects of spectral tuning of evening ambient light on melatonin suppression, alertness and sleep.

Physiol Behav. 2017 May 1. [Epub ahead of print]



Tucker MA, Morris CJ, Morgan A, Yang J, Myers S, Pierce JG, Stickgold R, Scheer F.

The relative impact of sleep and circadian drive on motor skill acquisition and memory consolidation.

Sleep. 2017 Apr 1;40(4):zsx036.



Balasingam M, Ebrahim J, Ariffin IA.

Tele-echocardiography - Made for astronauts, now in hospitals.

Indian Heart J. 2017 Mar-Apr;69(2):252-4.

Note: This article may be obtained online without charge.



Mazur LM, Mosaly PR, Tracton G, Stiegler MP, Adams RD, Chera BS, Marks LB.

Improving radiation oncology providers' workload and performance: Can simulation-based training help?

Pract Radiat Oncol. 2017 Feb 17. [Epub ahead of print]

Note: The NASA Task Load Index was used.



Zhang Y, Kumada T.

Relationship between workload and mind-wandering in simulated driving.

PLoS One. 2017 May 3;12(5):e0176962.

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.