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NASA Spaceline Current Awareness List #751 2 June 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Saturday, June 3, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,rertwine@nasaprs.com.

 

Please note: SPACELINE Current Awareness Lists are now available on the Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. A link appears on the main Menu. Lists from 2017 are available at this time, as well as links to the 2003-2011 Archives. The Lists published from 2012-2016 will be added at a later date.

 

Papers deriving from NASA support:

 

1

Pecaut MJ, Mao XW, Bellinger DL, Jonscher KR, Stodieck LS, Ferguson VL, Bateman TA, Mohney RP, Gridley DS.

Is spaceflight-induced immune dysfunction linked to systemic changes in metabolism?

PLoS One. 2017 May 24;12(5):e0174174.

https://www.ncbi.nlm.nih.gov/pubmed/28542224

Note: STS-135 results. This article may be obtained online without charge.

Journal Impact Factor: 3.057

Funding: "This study was supported by NASA managed cooperative agreement NNX10AJ31G and the LLUMC Department of Radiation Medicine."

 

2

Zwart SR, Gibson CR, Gregory JF, Mader TH, Stover PJ, Zeisel SH, Smith SM.

Astronaut ophthalmic syndrome.

FASEB J. 2017 May 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28546443

PI: S.M. Smith

Note: ISS results.

Journal Impact Factor: 5.299

Funding: "This work was supported by the National Aeronautics and Space Administration (NASA) Human Research Program’s Human Health Countermeasures Element."

 

3

Tirumalai MR, Karouia F, Tran Q, Stepanov VG, Bruce RJ, Ott CM, Pierson DL, Fox GE.

The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic.

npj Microgravity. 2017 May 23;3(1):15.

https://www.nature.com/articles/s41526-017-0020-1

PIs: D.L. Pierson, G.E. Fox

Note: A high aspect rotating vessel (HARV) was used. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "...the NASA URC at Texas Southern University under Cooperative Agreement NNX08BA47A." The PIs report funding through an internal project and NASA grant NNJ04HF43G.

 

4

Duke JW, Elliott JE, Laurie SS, Voelkel T, Gladstone IM, Fish MB, Lovering AT.

Relationship between quantitative and descriptive methods of studying blood flow through intrapulmonary arteriovenous anastomoses during exercise.

Respir Physiol Neurobiol. 2017 Sep;243:47-54. Epub 2017 May 20.

https://www.ncbi.nlm.nih.gov/pubmed/28536067

Journal Impact Factor: 1.773

Funding: "This research was supported by the Defense Medical Research & Development Program, Department of Defense GrantW81XWH-10-2-0114; Sacred Heart Medical Center Translational Award Program (ATL); Eugene & Clarissa Evonuk Memorial Graduate Fellowship in Environmental, Exercise, or Stress Physiology (SSL)." S.S. Laurie is affiliated with NASA Johnson Space Center.

 

5

Janssen K, Brand TC, Cunitz BW, Wang YN, Simon J, Starr F, Liggitt HD, Thiel J, Sorensen MD, Harper JD, Bailey MR, Dunmire B.

Safety and effectiveness of longer focal beam and burst duration in ultrasonic propulsion for repositioning urinary stones and fragments.

J Endourol. 2017 May 24. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28537452

PI: M.R. Bailey

Journal Impact Factor: 2.107

Funding: "This work was supported by the National Space Biomedical Research Institute through NASA NCC 958, National Institute of Diabetes and Digestive and Kidney Diseases grant P01 DK043881, and the Madigan Army Health System Department of Urology residency program. Some of this material is the result of work supported by resources from the VA Puget Sound Health Care System, Seattle, WA."

 

6

Chernyavskiy P, Edmondson EF, Weil MM, Little MP.

High-energy particle beam and gamma radiation exposure, familial relatedness and cancer in mice.

Br J Cancer. 2017 May 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28535153

PI: M.M. Weil

Journal Impact Factor: 5.569

Funding: "This work was supported by the Intramural Research Program of the National Institutes of Health, the National Cancer Institute Division of Cancer Epidemiology and Genetics and by grant NNX12AB54G from the National Aeronautics and Space Administration."

 

7

Mishra B, Ripperdan R, Ortiz L, Luderer U.

Very low doses of heavy oxygen ion radiation induce premature ovarian failure.

Reproduction. 2017 May 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28528322

PIs: U. Luderer; B. Mishra, NSBRI First Award Fellowship

Journal Impact Factor: 3.184

Funding: "Supported by National Aeronautics and Space Administration grant NNX14AC50G to UL; National Institutes of Health grant P30CA062203, the University of California Irvine (UC Irvine) Chao Family Comprehensive Cancer 368 Center; the Center for Occupational and Environmental Health, UC Irvine; the University of Virginia Center for Research in Reproduction Ligand Assay and Analysis Core, supported by the Eunice Kennedy Shriver NICHD/NIH (NCTRI) Grant P50-HD28934. BM was partially supported by a First award fellowship from the National Space Biomedical Research Institute grant PF04302."

 

8

Paul-Gilloteaux P, Potiron V, Delpon G, Supiot S, Chiavassa S, Paris F, Costes SV.

Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes.

Sci Rep. 2017 May 23;7(1):2280.

https://www.ncbi.nlm.nih.gov/pubmed/28536438

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.228

Funding: "This work was funded by Region Pays de la Loire (France) and la Ligue Contre le Cancer. The original computer model was developed with National Aeronautics and Space Administration funding [NNL15AA08I]."

 

9

Wu P, Morie J, Wall P, Ott T, Binsted K.

ANSIBLE: Virtual reality for behavioral health.

Procedia Eng. 2016;159:108-11.

http://www.sciencedirect.com/science/article/pii/S1877705816322792

PIs: P. Wu, K. Binsted

Note: This article may be obtained online without charge.

Journal Impact Factor: 0.73

Funding: "The above work was sponsored by NASA’s Human Research Program under contract #NNX14CJ06C."

______________________________________________________

 

Other papers of interest:

 

1

Gambara G, Salanova M, Ciciliot S, Furlan S, Gutsmann M, Schiffl G, Ungethuem U, Volpe P, Gunga HC, Blottner D.

Microgravity-induced transcriptome adaptation in mouse paraspinal longissimus dorsimuscle highlights insulin resistance-linked genes. 

Front Physiol. 2017 May 5;8:279.

https://www.ncbi.nlm.nih.gov/pubmed/28529490

Note: BION-M1 results. This article may be obtained online without charge.

 

2

Wakayama S, Kamada Y, Yamanaka K, Kohda T, Suzuki H, Shimazu T, Tada MN, Osada I, Nagamatsu A, Kamimura S, Nagatomo H, Mizutani E, Ishino F, Yano S, Wakayama T.

Healthy offspring from freeze-dried mouse spermatozoa held on the International Space Station for 9 months.

Proc Natl Acad Sci U S A. 2017 May 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28533361

Note: ISS results. This article may be obtained online without charge.

 

3

Shi K, Gu J, Guo H, Zhao L, Xie Y, Xiong H, Li J, Zhao S, Song X, Liu L.

Transcriptome and proteomic analyses reveal multiple differences associated with chloroplast development in the spaceflight-induced wheat albino mutant mta

PLoS One. 2017 May 24;12(5):e0177992.

https://www.ncbi.nlm.nih.gov/pubmed/28542341

Note: Results from plants grown from seeds flown on a Chinese satellite (Shijian 8). This article may be obtained online without charge.

 

4

Pao SI, Chien KH, Lin HT, Tai MC, Chen JT, Liang CM.

Effect of microgravity on the mesenchymal stem cell characteristics of limbal fibroblasts.

J Chin Med Assoc. 2017 May 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28529022

Note: A rotary cell culture system was used. This article may be obtained online without charge.

 

5

Šket R, Treichel N, Debevec T, Eiken O, Mekjavic I, Schloter M, Vital M, Chandler J, Tiedje JM, Murovec B, Prevoršek Z, Stres B.

Hypoxia and inactivity related physiological changes (constipation, inflammation) are not reflected at the level of gut metabolites and butyrate producing microbial community: The PlanHab Study. 

Front Physiol. 2017 May 4;8:250.

https://www.ncbi.nlm.nih.gov/pubmed/28522975

Note: Bed rest study. PlanHab is the Planetary Habitat simulation project supported by the European Union and the European Space Agency (ESA) (registration number NCT02637921 at https://clinicaltrials.gov/). This article may be obtained online without charge.

 

6

Silva-Martinez JP, Sorice Genaro A, Wen HA, Glauber N, Russomano T.

Remotely guided breast sonography for long-term space missions: A case report and discussion.

Telemed J E Health. 2017 May 24. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28537495

 

7                                                 

Kim YK, Kameo Y, Tanaka S, Adachi T.

Capturing microscopic features of bone remodeling into a macroscopic model based on biological rationales of bone adaptation.

Biomech Model Mechanobiol. 2017 May 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28523374

 

8

Allen CP, Hirakawa H, Nakajima NI, Moore S, Nie J, Sharma N, Sugiura M, Hoki Y, Araki R, Abe M, Okayasu R, Fujimori A, Nickoloff JA.

Low- and high-LET ionizing radiation induces delayed homologous recombination that persists for two weeks before resolving.

Radiat Res. 2017 May 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28535128

 

9

Zuma e Maia FC, Cal R, D'Albora R, Carmona S, Schubert MC.

Head-shaking tilt suppression: A clinical test to discern central from peripheral causes of vertigo.

J Neurol. 2017 May 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28536922

 

10

Kim K, Hirayama K, Yoshida K, Yano R, Abe M, Otsuki M, Sakuraba S, Sakai S.

Effect of exposure to short-wavelength light on susceptibility to motion sickness.

Neuroreport. 2017 May 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28538515

 

11

Tamura A, Wada Y, Inui T, Shiotani A.

Perceived direction of gravity and the body-axis during static whole body roll-tilt in healthy subjects.

Acta Otolaryngol. 2017 May 24:1-6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28537142

Note: A flight simulator was used. This article may be obtained online without charge.

 

12

Paradiso R, Arena C, De Micco V, Giordano M, Aronne G, De Pascale S.

Changes in leaf anatomical traits enhanced photosynthetic activity of soybean grown in hydroponics with plant growth-promoting microorganisms.

Front Plant Sci. 2017 May 5;8:674.

https://www.ncbi.nlm.nih.gov/pubmed/28529515

Note: This article may be obtained online without charge.

 

13

Neal V.

Spaceflight in the Shuttle era and beyond: Redefining humanity's purpose in space.

New Haven, CT: Yale University Press, 2017. 288 p.

http://yalebooks.yale.edu/book/9780300206517/spaceflight-shuttle-era-and-beyond

Note: From the Introduction: "This book probes the public meaning of human spaceflight during the space shuttle era by examining a variety of constructs or frameworks that shaped and communicated its rationale." Chapters include: 1) Spaceflight: Discerning its meaning, 2) Space Shuttle: Going to work in space, 3) Astronauts: Reinventing the right stuff, 4) Science: Doing research in space, 5) Space Station: Campaigning for a permanent human presence in space, 6) Plans: Envisioning the future in space, and 7) Memory: Preserving meaning.

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