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NASA Spaceline Current Awareness List #759 28 July 2017 (Space Life Science Research Results))

Status Report From: Spaceline
Posted: Friday, July 28, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,rertwine@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Be NA, Avila-Herrera A, Allen JE, Singh N, Checinska Sielaff A, Jaing C, Venkateswaran K.

Whole metagenome profiles of particulates collected from the International Space Station.

Microbiome. 2017 Jul 17;5(1):81.

https://www.ncbi.nlm.nih.gov/pubmed/28716113

PIs: K. Venkateswaran, C. Jaing

Note: ISS results. GeneLab: "Bacillus reads were mapped to assemblies of four B. cereussensu lato isolates previously recovered from the ISS. Assemblies were downloaded fromftp://ftp.cbcb.umd.edu/pub/data/issensis/asms/. The sequencing data for the assemblies of ISS Bacillus species are available from the NASA GeneLab system (accession: GLDS-64;https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-64/#)." This article may be obtained online without charge.

Journal Impact Factor: 8.496

Funding: "This research was funded by a 2012 Space Biology NNH12ZTT001N grant no. 19-12829-26 under Task Order NNN13D111T award to KV which also funded post-doctoral fellowship for AC and a JPL subcontract 1506453 to GEF. This work was performed under the auspices of the U.S. Department of Energy by the Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. In addition, the research carried out at the Lawrence Livermore National Laboratory was funded by a 2014 Space Biology NNH14ZTT002N grant no. NNX15AJ29G award to CJ which also funded JA, NB, and AAH."

 

2

Lee AG, Mader TH, Gibson CR, Tarver W.

Space flight-associated neuro-ocular syndrome.

JAMA Ophthalmol. 2017 Jul 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28727859

Note: ISS results.

Journal Impact Factor: 5.625

Funding: No funding cited. T.H. Mader and W. Tarver are affiliated with NASA Johnson Space Center.

 

3

Puglia I, Balsamo M, Vukich M, Zolesi V.

Long term microgravity effects on isometric hand grip and precision pinch force with visual and proprioceptive feedback.

Int J Aerosp Eng. 2017 Jul 20. [Article in Press]

https://www.hindawi.com/journals/ijae/aip/1952630/

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: 1.144

Funding: "This work has been supported by the Italian Space Agency (ASI) in the frame of the ASI-NASA Memorandum of Understanding (MOU) for the utilization of the International Space Station (ISS)."

 

4

Hassan T, Afshinnekoo E, Wu S, Mason CE.

Genetic and epigenetic heterogeneity and the impact on cancer relapse.

Exp Hematol. 2017 Jul 10. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28705639

PI: C.E. Mason

Journal Impact Factor: 2.82

Funding: "We would like to thank the Starr Cancer Consortium grants (I7-A765, I9-A9-071) and funding from the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, Bert L. and N Kuggie Vallee Foundation, the WorldQuant Foundation, The Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G, 15-15Omni2-0063), the Bill and Melinda Gates Foundation (OPP1151054)."

 

5

Strangman GE, Ivkovic V, Zhang Q.

Wearable brain imaging with multi-modal physiological recording.

J Appl Physiol (1985). 2017 Jul 13:jap.00297.2017. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28705994

PI: G. Strangman

Journal Impact Factor: 3.351

Funding: "This work was supported by the National Space Biomedical Research Institute through NASA NCC 9-58 and the National Football League Players Association (NFLPA)."

 

6

Mindock J, Lumpkins S, Anton W, Havenhill M, Shelhamer M, Canga M.

Integrating spaceflight human system risk research.

Acta Astronaut. 2017 Oct;139:306-12. Epub 2017 Jul 13.

http://www.sciencedirect.com/science/article/pii/S0094576517300759

Journal Impact Factor: 1.536

Funding: "This work was funded through NASA's Human Research Program." J. Mindock, S. Lumpkins, W. Anton, and M. Canga are affiliated with NASA Johnson Space Center. M. Havenhill is affiliated with NASA Glenn Research Center. M. Shelhamer was affiliated with NASA Johnson Space Center at the time of the study.

 

7

Steinberg LM, Kronyak RE, House CH.

Coupling of anaerobic waste treatment to produce protein- and lipid-rich bacterial biomass.

Life Sci Space Res. 2017 Nov;15:32-42. Epub 2017 Jul 20.

http://www.sciencedirect.com/science/article/pii/S221455241730041X

Journal Impact Factor: 1.97

Funding: "Funding for this work was provided by the Ralph Steckler/Space Grant Space Colonization Research and Technology Development Opportunity (09-STECKLER09-0022) through the NASA Office of Education's Space Grant program. The project was also partially supported by the Penn State Astrobiology Research Center (through the NASA Astrobiology Institute, cooperative agreement #NNA09DA76A)."

______________________________________________________

 

Other papers of interest:

 

1

Pelligra S, Gossman W.

Aerospace, health maintenance, wellness.

In: StatPearls. Treasure Island (FL): StatPearls Publishing, June 2017.

https://www.ncbi.nlm.nih.gov/pubmed/28722944

Note: Results from Mercury, Gemini, Apollo, Skylab, Shuttle, and ISS missions are discussed. This article may be obtained online without charge.

 

2

Morohashi K, Okamoto M, Yamazaki C, Fujii N, Miyazawa Y, Kamada M, Kasahara H, Osada I, Shimazu T, Fusejima Y, Higashibata A, Yamazaki T, Ishioka N, Kobayashi A, Takahashi H. 

Gravitropism interferes with hydrotropism via counteracting auxin dynamics in cucumber roots: Clinorotation and spaceflight experiments.

New Phytol. 2017 Jul 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28722158

Note: ISS results. A 3D clinostat was used in ground experiments.

 

3

La Barbera G, Capriotti AL, Michelini E, Piovesana S, Calabretta MM, Chiozzi RZ, Roda A, Laganà A.

Proteomic analysis and bioluminescent reporter gene assays to investigate effects of simulated microgravity on Caco-2 cells.

Proteomics. 2017 Jul 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28727291

Note: A 2D clinostat was used.

 

4

Sheet S, Sathishkumar Y, Sivakumar AS, Shim KS, Lee YS.

Low-shear-modeled microgravity-grown Penicillium chrysogenum-mediated biosynthesis of silver nanoparticles with enhanced antimicrobial activity and its anticancer effect in human liver cancer and fibroblast cells.

Bioprocess Biosyst Eng. 2017 Jul 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28710569

Note: A high aspect ratio vessel was used.

 

5

Zhao J, Ma H, Wu L, Cao L, Yang Q, Dong H, Wang Z, Ma J, Li Z.

The influence of simulated microgravity on proliferation and apoptosis in U251 glioma cells.

In Vitro Cell Dev Biol Anim. 2017 Jul 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28707224

Note: A 2D clinostat was used.

 

6

Kitazawa T, Kitazawa K.

Prolonged bed rest impairs rapid CPI-17 phosphorylation and contraction in rat mesenteric resistance arteries to cause orthostatic hypotension.

Pflugers Arch. 2017 Jul 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28717991

Note: Bed rest study.

 

7

Franchi MV, Reeves ND, Narici MV.

Skeletal muscle remodeling in response to eccentric vs. concentric loading: Morphological, molecular, and metabolic adaptations.

Front Physiol. 2017 Jul 4;8:447. Review.

https://www.ncbi.nlm.nih.gov/pubmed/28725197

Note: This article may be obtained online without charge.

 

8

Hirunsai M, Srikuea R.

Differential effects of heat stress on fibre capillarisation in tenotomised soleus and plantaris muscles.

Int J Hyperthermia. 2017 Jul 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28720001

 

9

Lomonosova YN, Belova SP, Mirzoev TM, Kozlovskaya IB, Shenkman BS.

Eukaryotic elongation factor 2 kinase activation in M. soleus under 14-day hindlimb unloading of rats.

Dokl Biochem Biophys. 2017 May;474(1):165-7.

https://www.ncbi.nlm.nih.gov/pubmed/28726101

Note: Hindlimb unloading study.

 

10

Ratchford SM, Lavin KM, Perkins RK, Jemiolo B, Trappe SW, Trappe TA.

Aspirin as a COX inhibitor and anti-inflammatory drug in human skeletal muscle.

J Appl Physiol (1985). 2017 Jul 13:jap.01119.2016. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28706001

 

11

Reidy PT, Lindsay CC, McKenzie AI, Fry CS, Supiano MA, Marcus RL, LaStayo PC, Drummond MJ.

Aging-related effects of bed rest followed by eccentric exercise rehabilitation on skeletal muscle macrophages and insulin sensitivity.

Exp Gerontol. 2017 Jul 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28705613

Note: Bed rest study.

 

12

Standley RA, Distefano G, Pereira SL, Tian M, Kelly OJ, Coen PM, Deutz NEP, Wolfe RR, Goodpaster BH.

Effects of beta-hydroxy-beta-methylbutyrate (HMB) on skeletal muscle mitochondrial content and dynamics, and lipids after 10 days of bed rest in older adults.

J Appl Physiol (1985). 2017 Jul 13:jap.00192.2017. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28705993

Note: Bed rest study.

 

13

Black DM, Cauley JA, Wagman R, Ensrud K, Fink HA, Hillier TA, Lui LY, Cummings SR, Schousboe JT, Napoli N.

The ability of a single BMD and fracture history assessment to predict fracture over 25 years in postmenopausal women: The study of osteoporotic fractures.

J Bone Miner Res. 2017 Jul 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28719727

 

14

Karasik D, Demissie S, Lu D, Broe KE, Boyd SK, Liu CT, Hsu YH, Bouxsein ML, Kiel DP.

Bone strength estimated by micro-finite element analysis (microFEA) is heritable and shares genetic predisposition with areal BMD: The Framingham Study.

J Bone Miner Res. 2017 Jul 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28722129

 

15

Popp KL, Hughes JM, Martinez-Betancourt A, Scott M, Turkington V, Caksa S, Guerriere KI, Ackerman KE, Xu C, Unnikrishnan G, Reifman J, Bouxsein ML.

Bone mass, microarchitecture and strength are influenced by race/ethnicity in young adult men and women.

Bone. 2017 Jul 13;103:200-8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28712877

 

16

Sun W, Yang Y, Yu H, Wang L, Pan S.

The synergistic effect of microwave radiation and hypergravity on rats and the intervention effect of Rana sylvatica Le Conte oil.

Dose Response. 2017 Jun 30;15(2):1559325817711511.

https://www.ncbi.nlm.nih.gov/pubmed/28717348

Note: Centrifugation was used. This article may be obtained online without charge.

 

17

Rosenman ED, Dixon AJ, Webb JM, Brolliar S, Golden SJ, Jones KA, Shah S, Grand JA, Kozlowski SWJ, Chao GT, Fernandez R.

A simulation-based approach to measuring team situational awareness in emergency medicine: A multicenter, observational study.

Acad Emerg Med. 2017 Jul 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28715105

 

18

Dixit JP, Jagtap SS, Kamble SM, Vidyasagar PB.

Effects of short-term hypergravity exposure are reversible in Triticum aestivum L. Caryopses. 

Microgravity Sci Technol. 2017 Jul 21. [Article in Press]

https://link.springer.com/article/10.1007%2Fs12217-017-9553-x

Note: Centrifugation was used.

 

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