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NASA Spaceline Current Awareness List #760 4 August 2017 (Space Life Science Research Results))

Status Report From: Spaceline
Posted: Friday, August 4, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,rertwine@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Rettig TA, Ward C, Pecaut MJ, Chapes SK.

Validation of methods to assess the immunoglobulin gene repertoire in tissues obtained from mice on the International Space Station.

Gravit Space Res. 2017 Jul;5(1):2-23.

http://gravitationalandspacebiology.org/index.php/journal/article/view/750

PIs: M.J. Pecaut, S.K. Chapes

Note: ISS results. GeneLab: "The MiSeq® workflow described above was modified to analyze mouse liver transcriptomic data from the Rodent Research 1 (RR1) NASA validation flight provided by the NASA GeneLab program (https://genelab-data.ndc.nasa.gov/genelab/, Accession Numbers: GLDS-47, GLDS-48)." This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA grants NNX13AN34G and NNX15AB45G, NIH grant GM103418, the Molecular Biology Core supported by the College of Veterinary Medicine at Kansas State University, and the Kansas State University Johnson Cancer Center."

 

2

Massa GD, Newsham G, Hummerick ME, Morrow RC, Wheeler RM.

Plant pillow preparation for the Veggie plant growth system on the International SpaceStation.

Gravit Space Res. 2017 Jul;5(1):24-34.

http://gravitationalandspacebiology.org/index.php/journal/article/view/749

PI: G.D. Massa

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA’s Division of Space Life and Physical Sciences Research and Applications."

 

3

Frippiat JP, Crucian BE, de Quervain DJ, Grimm D, Montano N, Praun S, Roozendaal B, Schelling G, Thiel M, Ullrich O, Choukèr A.

Towards human exploration of space: The THESEUS review series on immunology research priorities.

npj Microgravity. 2016 Dec;2:16040. Review.

https://www.ncbi.nlm.nih.gov/pubmed/28725745

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This review is a product of the Theseus Project: Towards Human Exploration of Space: a European Strategy of the European Science Foundation and was supported by European Community’s 7th Framework Programme (FP7/2007–2013) under grant agreement #242482. We also thank the French (CNES), the German (DLR), the Italian (ASI), the Russian (IBMP, Rocosmos) and the American (NASA) space agencies for their support." B. E. Crucian is affiliated with NASA Johnson Space Center.

 

4

Mao XW, Nishiyama NC, Campbell-Beachler M, Gifford P, Haynes KE, Gridley DS, Pecaut MJ.

Role of NADPH oxidase as a mediator of oxidative damage in low-dose irradiated and hindlimb-unloaded mice.

Radiat Res. 2017 Aug 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28763287

Note: Hindlimb unloading study.

PI: X.W. Mao

Journal Impact Factor: 2.539

Funding: "This study was supported by National Aeronautics and Space Administration (NASA grant no. NNX13AL97G) and the Department of Basic Sciences, Loma Linda University."

 

5

Werner E, Wang Y, Doetsch PW.

A single exposure to low- or high-LET radiation induces persistent genomic damage in mouse epithelial cells in vitro and in lung tissue.

Radiat Res. 2017 Jul 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28753066

PIs: Y. Wang/P.W. Doetsch/NSCOR

Journal Impact Factor: 2.539

Funding: "This research project was supported in part by the Emory University Integrated Cellular Imaging Microscopy Core of the Winship Cancer Institute comprehensive cancer center grant, no. P30CA138292. This work was funded by NASA NSCOR grant no. NNX11AC30G and DoD grant no. W81XWH-17-1-0187 to PD and NNX11AC30G to YW."

 

6

Nielsen C, Rahman A, Rehman AU, Walsh MK, Miller CD.

Food waste conversion to microbial polyhydroxyalkanoates.

Microb Biotechnol. 2017 Jul 24. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28736901

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.513

Funding: "Asad Ur Rehman was supported by a U.S. Fulbright Scholarship." A. Rahman is affiliated with NASA Ames Research Center. 

 

7

Smith DJ, Sowa MB.

Ballooning for biologists: Mission essentials for flying life science experiments to near space.

Gravit Space Res. 2017 Jul;5(1):52-73. Review.

http://gravitationalandspacebiology.org/index.php/journal/article/view/737

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: No funding cited. D.J. Smith and M.B. Sowa are affiliated with NASA Ames Research Center.

______________________________________________________

 

Other papers of interest:

 

1

Zhao L, Rui Q, Wang D.

Molecular basis for oxidative stress induced by simulated microgravity in nematodeCaenorhabditis elegans

Sci Total Environ. 2017 Dec;607-608:1381-90. Epub 2017 Jul 19.

https://www.ncbi.nlm.nih.gov/pubmed/28738528

Note: A Rotary Cell Culture System was used.

 

2

Arun RP, Sivanesan D, Vidyasekar P, Verma RS.

PTEN/FOXO3/AKT pathway regulates cell death and mediates morphogenetic differentiation of colorectal cancer cells under simulated microgravity.

Sci Rep. 2017 Jul 20;7(1):5952.

https://www.ncbi.nlm.nih.gov/pubmed/28729699

Note: A Rotational Cell Culture System was used. This article may be obtained online without charge.

 

3

Ogoh S, Hirasawa A, de Abreu S, Denise P, Normand H.

Internal carotid, external carotid and vertebral artery blood flow responses to a 3-day of head-out dry immersion.

Exp Physiol. 2017 Jul 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28744943

Note: Dry immersion was used to simulate weightlessness.

 

4

Lautridou J, Buzzacott P, Belhomme M, Dugrenot E, Lafère P, Balestra C, Guerrero F.

Evidence of heritable determinants of decompression sickness in rats.

Med Sci Sports Exerc. 2017 Jul 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28731987

 

5

Matsumoto T, Ono T, Ishikura H, Aihara K, Sato Y, Tasaka A, Umei N, Tsumiyama W, Oki S.

Effects of joint immobilization and hindlimb unloading on collagen fibers of soleus muscles in rats.

J Phys Ther Sci. 2017 Jul;29(7):1192-5.

https://www.ncbi.nlm.nih.gov/pubmed/28744045

Note: Hindlimb unloading was used. Joint fixation was accomplished with non-elastic tape. This article may be obtained online without charge.

 

6

Perry RA, Martin JL, Vickers SD, Cesarz GM, Bai L, Selimovic EA, Muntis F, Parmar PJ, Caruso JF.

Lower leg anthropometry as a correlate to performance and metabolism from dynamic exercise.

Gravit Space Res. 2017 Jul;5(1):41-51.

http://gravitationalandspacebiology.org/index.php/journal/article/view/765

Note: This article may be obtained online without charge.

 

7

Takemura A, Roy RR, Yoshihara I, Ishihara A.

Unloading-induced atrophy and decreased oxidative capacity of the soleus muscle in rats are reversed by pre- and postconditioning with mild hyperbaric oxygen.

Physiol Rep. 2017 Jul;5(14).

https://www.ncbi.nlm.nih.gov/pubmed/28743823

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

8

Johannesdottir F, Thrall E, Muller J, Keaveny TM, Kopperdahl DL, Bouxsein ML.

Comparison of non-invasive assessments of strength of the proximal femur.

Bone. 2017 Jul 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28739416

 

9

Scheuren A, Wehrle E, Flohr F, Müller R.

Bone mechanobiology in mice: toward single-cell in vivo mechanomics.

Biomech Model Mechanobiol. 2017 Jul 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28735414

 

10

Swanson C, Shea SA, Wolfe P, Markwardt S, Cain SW, Munch M, Czeisler CA, Orwoll ES, Buxton OM.

24-hour profile of serum sclerostin and its association with bone biomarkers in men.

Osteoporos Int. 2017 Jul 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28744601

 

11

Miller AC, Rivas R, McMahon R, Miller K, Tesoro L, Villa V, Yanushkevich D, Lison P.

Radiation protection and mitigation potential of phenylbutyrate: Delivered via oral administration.

Int J Radiat Biol. 2017 Jul 27:1-13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28749244

 

12

Tharmalingam S, Sreetharan S, Kulesza AV, Boreham DR, Tai TC.

Low-dose ionizing radiation exposure, oxidative stress and epigenetic programing of health and disease.

Radiat Res. 2017 Jul 28. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28753061

 

13

Lim K, Wang W, Merfeld DM.

Unbounded evidence accumulation characterizes subjective visual vertical (SVV) forced-choice perceptual choice and confidence.

J Neurophysiol. 2017 Jul 26:jn.00318.2017. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28747465

 

14

Lacerenza CN, Reyes DL, Marlow SL, Joseph DL, Salas E.

Leadership training design, delivery, and implementation: A meta-analysis.

J Appl Psychol. 2017 Jul 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28749153

 

15                                                                         

Reinerman-Jones L, Barber DJ, Szalma JL, Hancock PA.

Human interaction with robotic systems: Performance and workload evaluations.

Ergonomics. 2017 Jul 26:1-18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28745552

 

16

Kovacs GTA, Shadden M.

Analysis of age as a factor in NASA astronaut selection and career landmarks.

PLoS One. 2017 Jul 27;12(7):e0181381.

https://www.ncbi.nlm.nih.gov/pubmed/28749968

Note: This article may be obtained online without charge.

 

17

Lüthen C, Jaschinski N.

Pressure suits for suborbital spaceflight - mandatory or not?

Space Safety Eng. 2017 Jul 26. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2468896717300605

 

18

Pu Y, Luo X, Bassham DC.

TOR-dependent and -independent pathways regulate autophagy in Arabidopsis thaliana

Front Plant Sci. 2017 Jul 11;8:1204.

https://www.ncbi.nlm.nih.gov/pubmed/28744293

Note: This article may be obtained online without charge.

 

19

Wang P, Mugume Y, Bassham DC.

New advances in autophagy in plants: Regulation, selectivity and function.

Semin Cell Dev Biol. 2017 Jul 20. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28734771

 

// end //

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