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NASA Spaceline Current Awareness List #768 6 October 2017 (Space Life Science Research Results))

Status Report From: Spaceline
Posted: Friday, October 6, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.

Papers deriving from NASA support:

1

Blaber EA, Pecaut MJ, Jonscher KR.

Spaceflight activates autophagy programs and the proteasome in mouse liver.

Int J Mol Sci. 2017 Sep 27;18(10):2062.

https://www.ncbi.nlm.nih.gov/pubmed/28953266

PI: M.J. Pecaut

Note: STS-135 results. This article may be obtained online without charge. GeneLab: "Transcriptomics and metabolomics data are publicly accessible via the NASA GeneLab data base. Transcriptomics data are found at the website (Available online: https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-25/). Metabolomics data are available at the website (Available online: https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-108/ )."

Journal Impact Factor: 3.226

Funding: "Michael J. Pecaut appreciates funding from NASA (NNX13AN34G)."

 

2

Garcia KM, Harrison MF, Sargsyan AE, Ebert D, Dulchavsky SA.

Real-time ultrasound assessment of astronaut spinal anatomy and disorders on the International Space Station.

J Ultrasound Med. 2017 Sep 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28 960477

PI: S.A. Dulchavsky

Note: ISS results.

Journal Impact Factor: 1.547

Funding: "This research was supported by the National Aeronautics and Space Administration (NASA) through NASA grant NNX10AM34G."

 

3

O'Hara NB, Reed HJ, Afshinnekoo E, Harvin D, Caplan N, Rosen G, Frye B, Woloszynek S, Ounit R, Levy S, Butler E, Mason CE.

Metagenomic characterization of ambulances across the USA.

Microbiome. 2017 Sep 22;5(1):125.

https://www.ncbi.nlm.nih.gov/pubmed/28938903

PI: C.E. Mason

Note: This article may be obtained online without charge.

Journal Impact Factor: 8.496

Funding: "Funding was provided by the Elisha M. Friedman Postdoctoral Fellowship to NO, an NSF grant #1120622 to GR, and for CM the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, Bert L and N Kuggie Vallee Foundation, the WorldQuant Foundation, The Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G, 15-15Omni2-0063), the National Institutes of Health (R01AI125416), the Bill and Melinda Gates Foundation (OPP1151054), and the Alfred P. Sloan Foundation (G-2015-13,964)."

 

4

McIntyre ABR, Ounit R, Afshinnekoo E, Prill RJ, Hénaff E, Alexander N, Minot SS, Danko D, Foox J, Ahsanuddin S, Tighe S, Hasan NA, Subramanian P, Moffat K, Levy S, Lonardi S, Greenfield N, Colwell RR, Rosen GL, Mason CE.

Comprehensive benchmarking and ensemble approaches for metagenomic classifiers.

Genome Biol. 2017 Sep 21;18(1):182.

https://www.ncbi.nlm.nih.gov/pubmed/28934964

PI: C.E. Mason

Note: This article may be obtained online without charge.

Journal Impact Factor: 11.908

Funding: "We would also like to thank the Epigenomics Core Facility at Weill Cornell Medicine as well as the Starr Cancer Consortium grants (I9-A9-071) and funding from the Irma T. Hirschl and Monique Weill-Caulier Charitable Trusts, Bert L. and N. Kuggie Vallee Foundation, the WorldQuant Foundation, The Pershing Square Sohn Cancer Research Alliance, NASA (NNX14AH50G, NNX17AB26G), the National Institutes of Health (R25EB020393, R01AI125416, R01ES021006), the National Science Foundation (grant no. 1120622), the Bill and Melinda Gates Foundation (OPP1151054), and the Alfred P. Sloan Foundation (G-2015-13964). Support was also provided by the Tri-Institutional Training Program in Computational Biology and Medicine and the Clinical and Translational Science Center (Jeff Zhu)."

 

5

Craig JC, Broxterman RM, Wilcox SL, Chen C, Barstow TJ.

Effect of adipose tissue thickness, muscle site, and sex on near-infrared spectroscopy derived total-[hemoglobin + myoglobin].

J Appl Physiol (1985). 2017 Sep 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28935822

PI: T.J. Barstow

Journal Impact Factor: 3.351

Funding: "This work was supported by National Aeronautics and Space Administration (NASA) Grant NNX10AK60G awarded to T. J. Barstow and by NASA Experimental Program to Stimulate Competitive Research Grant NNX11AM05A supporting R. M. Broxterman."

 

6

Patel R, Arakawa H, Radivoyevic T, Gerson SL, Welford SM.

Long-term deficits in behavior performances caused by low- and high-linear energy transfer radiation.

Radiat Res. 2017 Sep 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28961076

PI: S.L. Gerson

Journal Impact Factor: 2.359

Funding: "This research was funded by the National Aeronautics and Space Administration (NASA), grant no. NNJ13ZSA001N."

 

7

Ruitenberg MFL, De Dios YE, Gadd NE, Wood SJ, Reuter-Lorenz PA, Kofman I, Bloomberg JJ, Mulavara AP, Seidler RD.

Multi-day adaptation and savings in manual and locomotor tasks.

J Mot Behav. 2017 Sep 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28937868

PIs: R.D. Seidler, A. Mulavara, J.J. Bloomberg

Journal Impact Factor: 1.327

Funding: "This work was supported by the National Aeronautics and Space Administration (NASA; grant number NNX11AR02G), and in part by grants from the National Space Biomedical Research Institute through NASA NCC 9–58 (SA03801 and SA02801)."

 

8

Goel N.

Neurobehavioral effects and biomarkers of sleep loss in healthy adults.

Curr Neurol Neurosci Rep. 2017 Sep 25;17(11):89. Review.

https://www.ncbi.nlm.nih.gov/pubmed/28944399

PI: N. Goel

Journal Impact Factor: 3.345

Funding: "Preparation of this manuscript was supported by National Aeronautics and Space AdministrationNNX14AN49G (to NG)."

 

9

Grant LK, Cain SW, Chang AM, Saxena R, Czeisler CA, Anderson C.

Impaired cognitive flexibility during sleep deprivation among carriers of the Brain Derived Neurotrophic Factor (BDNF) Val66Met allele.

Behav Brain Res. 2017 Sep 22. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28947280

PI: C.A. Czeisler

Journal Impact Factor: 3.002

Funding: "This study was supported by the National Space and Biomedical Research Institute (NSBRI) grant HFP01601. Inpatient studies were conducted in the CTSC and supported in part by ULI RR025758 from the National Center for Research Resources (NCRR) or the National Institutes of Health (NIH)."

 

10

Smith-Jentsch KA, Sierra MJ.

Teamwork training needs analysis for long-duration exploration missions.

Houston, TX: NASA Johnson Space Center, 2017 Sep. 52 p. NASA/TM-2017-219294.

https://ston.jsc.nasa.gov/collections/TRS/listfiles.cgi?DOC=TM-2017-219294

Note: This publication may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: Funded by NASA NNJ15HP08P.

 

11

Schneider VI, Healy AF, Kole JA, Barshi I.

Does spatial information impact immediate verbatim recall of verbal navigation instructions?

Psychon Bull Rev. 2017 Sep 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28948562

Journal Impact Factor: 2.921

Funding: "This research was supported in part by National Aeronautics and Space Administration Grants NCC2-1310, NNA07CN59A, NNX10AC87A, and NNX14AB75A."

______________________________________________________

 

 

Other papers of interest:

 

1

Wuest SL, Roesch C, Ille F, Egli M.

Calcium dependent current recordings in Xenopus laevis oocytes in microgravity.

Acta Astronaut. 2017 Oct 2. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576517310913

Note: Parabolic flight results.

 

2

Fortrat JO, de Holanda A, Zuj K, Gauquelin-Koch G, Gharib C.

Altered venous function during long-duration spaceflights.

Front Physiol. 2017 Sep 12;8:694.

https://www.ncbi.nlm.nih.gov/pubmed/28955249

Note: ISS results. This article may be obtained online without charge.

 

3

Jamalian S, Jafarnejad M, Zawieja SD, Bertram CD, Gashev AA, Zawieja DC, Davis MJ, Moore JE Jr.

Demonstration and analysis of the suction effect for pumping lymph from tissue beds at subatmospheric pressure.

Sci Rep. 2017 Sep 21;7(1):12080.

https://www.ncbi.nlm.nih.gov/pubmed/28935890

Note: This article may be obtained online without charge.

 

4

Marqueti RC, Durigan JLQ, Oliveira AJS, Mekaro MS, Guzzoni V, Aro AA, Pimentel ER, Selistre-de-Araujo HS.

Effects of aging and resistance training in rat tendon remodeling.

FASEB J. 2017 Sep 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28899880

 

5

Kim J, Montagne K, Nemoto H, Ushida T, Furukawa KS.

Hypergravity down-regulates c-fos gene expression via ROCK/Rho-GTP and the PI3K signaling pathway in murine ATDC5 chondroprogenitor cells.

PLoS One. 2017 Sep 27;12(9):e0185394.

https://www.ncbi.nlm.nih.gov/pubmed/28953959

Note: Centrifugation was used. This article may be obtained online without charge.

 

6

Bak EN, Larsen MG, Moeller R, Nissen SB, Jensen LR, Nornberg P, Jensen SJK, Finster K.

Silicates eroded under simulated Martian conditions effectively kill bacteria—A challenge for life on Mars.

Front Microbiol. 2017 Sep 12;8:1709.

https://www.ncbi.nlm.nih.gov/pubmed/28955310

Note: This article may be obtained online without charge.

 

7

Hosoyama T, Ichida S, Kanno M, Ishihara R, Hatashima T, Ueno K, Hamano K.

Microgravity influences maintenance of the human muscle stem/progenitor cell pool.

Biochem Biophys Res Commun. 2017 Sep 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28942144

Note: A clinostat was used. This article may be obtained online without charge.

 

8

Theeuwes WF, Gosker HR, Langen RCJ, Verhees KJP, Pansters NAM, Schols A, Remels AHV.

Inactivation of glycogen synthase kinase-3β (GSK-3β) enhances skeletal muscle oxidative metabolism.

Biochim Biophys Acta. 2017 Sep 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28943449

Note: Hindlimb unloading study.

 

9

Tong L, Zhu G, Wang J, Sun R, He F, Zhai J.

Suppressing angiogenesis regulates the irradiation-induced stimulation on osteoclastogenesis in vitro.

J Cell Physiol. 2017 Sep 23. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/28941279

 

10

Greenlee MW.

Self-motion perception: Ups and downs of multisensory integration and conflict detection.

Curr Biol. 2017 Sep 25;27(18):R1006-R7.

https://www.ncbi.nlm.nih.gov/pubmed/28950080

 

11

Head J, Tenan MS, Tweedell AJ, LaFiandra ME, Morelli F, Wilson KM, Ortega SV, Helton WS.

Prior mental fatigue impairs marksmanship decision performance.

Front Physiol. 2017 Sep 8;8:680.

https://www.ncbi.nlm.nih.gov/pubmed/28951724

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

 

12

Chen Y, Ju L, Rushdi M, Ge C, Zhu C.

Receptor-mediated cell mechanosensing.

Mol Biol Cell. 2017 Sep 27. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/28954860

Note: This article may be obtained online without charge.

 

13

Serrano JC, Cora-Cruz J, Diffoot-Carlo N, Sundaram PA.

Adaptive responses of murine osteoblasts subjected to coupled mechanical stimuli.

J Mech Behav Biomed Mater. 2017 Sep 14;77:250-7.

https://www.ncbi.nlm.nih.gov/pubmed/28957700

 

14

Kyriacou MC, De Pascale S, Kyratzis A, Rouphael Y.

Microgreens as a component of space life support systems: A cornucopia of functional food.

Front Plant Sci. 2017 Sep 12;8:1587.

https://www.ncbi.nlm.nih.gov/pubmed/28955372

Note: This article may be obtained online without charge.

 

15

Villani ME, Massa S, Lopresto V, Pinto R, Salzano AM, Scaloni A, Benvenuto E, Desiderio A.

Effects of high-intensity static magnetic fields on a root-based bioreactor system for space applications.

Life Sci Space Res. 2017 Sep 28. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552417300652

// end //

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