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NASA Spaceline Current Awareness List #773 9 November 2017 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Thursday, November 9, 2017

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.

Papers deriving from NASA support:

1

Roberts DR, Albrecht MH, Collins HR, Asemani D, Chatterjee AR, Spampinato MV, Zhu X, Chimowitz MI, Antonucci MU.

Effects of spaceflight on astronaut brain structure as indicated on MRI.

N Engl J Med. 2017 Nov 2;377(18):1746-53.

https://www.ncbi.nlm.nih.gov/pubmed/29091569

PI: D.R. Roberts

Note: ISS and STS results.

Journal Impact Factor: 72.406

Funding: "Supported by a grant (NNX13AJ92G) from the National Aeronautics and Space Administration (NASA)."

 

2

Reschke MF, Kolev OI, Clément G.

Eye-head coordination in 31 Space Shuttle astronauts during visual target acquisition.

Sci Rep. 2017 Oct 27;7(1):14283.

https://www.ncbi.nlm.nih.gov/pubmed/29079792

PI: M.F. Reschke

Note: STS results. This article may be obtained online without charge.

Journal Impact Factor: 4.259

Funding: "This study was funded by the Extended Duration Orbiter Medical Project of the NASA Johnson Space Center Space Life Sciences Directorate (Reschke) and Centre National d’Etudes Spatiales (Clément)."

 

3

Zupanska AK, Schultz ER, Yao J, Sng NJ, Zhou M, Callaham JB, Ferl RJ, Paul AL.

ARG1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight.

Astrobiology. 2017 Oct 31. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29088549

PIs: R.J. Ferl, A-L. Paul

Note: ISS results; BRIC-17 experiments.

Journal Impact Factor: 2.603

Funding: "This work was supported by grants NNX12AK80G and NNX12AN69G to R.J. Ferl and A.-L. Paul from NASA Space Life and Physical Sciences managed through Kennedy Space Center."

 

4

Escamilla CO, Filonova I, Walker AK, Xuan ZX, Holehonnur R, Espinosa F, Liu S, Thyme SB, López-Garcia IA, Mendoza DB, Usui N, Ellegood J, Eisch AJ, Konopka G, Lerch JP, Schier AF, Speed HE, Powell CM.

Kctd13 deletion reduces synaptic transmission via increased RhoA.

Nature. 2017 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29088697

PI: A.J. Eisch

Journal Impact Factor: 40.137

Funding: "This research was supported by National Institutes of Health (NIH) R01HD069560 and R01HD069560-S1, Autism Speaks, The Hartwell Foundation, Ed and Sue Rose Distinguished Professorship in Neurology, gifts from C. Heighten, D. Caudy and BRAINS for Autism (to C.M.P.), Autism Science Foundation (to C.M.P. and C.O.E.), Canadian Institute for Health Research and Ontario Brain Institute (to J.P.L.), NIH 2K02DA023555 and NASA NNX15AE09G (to A.J.E.), Uehara Foundation (to N.U.), NIH MH102603 (to G.K.), NIH K99MH110603 (to S.B.T.), Damon Runyon Cancer Research Foundation (to S.B.T.), Harvard Brain Institute Bipolar Seed Grant (to A.F.S.), and NIH R01HL109525 (to A.F.S)."

 

5

Gibbs NM, Rouhana LV, Masson PH.

Quantitative trait loci for root growth response to cadaverine in Arabidopsis.

Methods Mol Biol. 2018;1694:233-56. Epub 2017 Oct 28.

https://www.ncbi.nlm.nih.gov/pubmed/29080172

PI: P.H. Masson

Journal Impact Factor: 0.79

Funding: "Our work was made possible by grants from the National Science Foundation (IOS-1121694), the National Aeronautics and Space Administration (NNX14AT23G), and the University of Wisconsin–Madison College of Agricultural and Life Sciences Hatch program."

______________________________________________________

 

 

Other papers of interest:

 

1

De Abreu S, Amirova L, Murphy R, Wallace R, Twomey L, Gauquelin-Koch G, Raverot V, Larcher F, Custaud MA, Navasiolava N.

Multi-system deconditioning in 3-day dry immersion without daily raise.

Front Physiol. 2017 Oct 13;8:799.

https://www.ncbi.nlm.nih.gov/pubmed/29081752

Note: Dry immersion was used. This article may be obtained online without charge.

 

2

Liphardt AM, Farnsworth AM, Andriacchi TP, Achtzehn S, Heer M, Mester J.

Sensitivity of serum concentration of cartilage biomarkers to 21-days of bed rest.

J Orthop Res. 2017 Oct 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29077223

Note: Bed rest study.

 

3

Ramos Gonzalez M, Caldwell JT, Branch PA, Wardlow GC, Black CD, Campbell J, Larson RD, Ade CJ.

Impact of shear rate pattern on post-occlusive near-infrared spectroscopy microvascular reactivity.

Microvasc Res. 2018 Mar;116:50-6. Epub 2017 Nov 6.

https://www.ncbi.nlm.nih.gov/pubmed/29080792

 

4

Buravkova LB, Rudimov EG, Andreeva ER, Grigoriev AI.

The ICAM-1 expression level determines the susceptibility of human endothelial cells to simulated microgravity.

J Cell Biochem. 2017 Oct 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/

Note: A Random Positioning Machine was used.

 

5

Hammond TG, Birdsall HH.

Hepatocyte CYP2B6 can be expressed in cell culture systems by exerting physiological levels of shear: Implications for ADME testing.

J Toxicol. 2017;2017:1907952. Review.

https://www.ncbi.nlm.nih.gov/pubmed/29081796

Note: This article may be obtained online without charge.

 

6

Nishimura H, Yamasaki M.

Changes in blood pressure, blood flow toward head and heart rate during 90 deg head-up tilting for 30 min in anaesthetized male rats.

Exp Physiol. 2017 Oct 30. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29086448

Note: Head up tilt study.

 

7

Kermorgant M, Leca F, Nasr N, Custaud MA, Geeraerts T, Czosnyka M, Arvanitis DN, Senard JM, Pavy-Le Traon A.

Impacts of simulated weightlessness by dry immersion on optic nerve sheath diameter and cerebral autoregulation.

Front Physiol. 2017 Oct 12;8:780.

https://www.ncbi.nlm.nih.gov/pubmed/29075198

Note: Dry immersion was used. This article may be obtained online without charge.

 

8

McGuire JA, Sherman PM, Dean E, Bernot JM, Rowland LM, McGuire SA, Kochunov PV.

Utilization of MRI for cerebral white matter injury in a hypobaric swine model—Validation of technique.

Mil Med. 2017 May;182(5):e1757-64.

https://www.ncbi.nlm.nih.gov/pubmed/29087921

Note: This article may be obtained online without charge.

 

9

Chikara S, Mamidi S, Sreedasyam A, Chittem K, Pietrofesa R, Zuppa A, Moorthy G, Dyer N, Christofidou-Solomidou M, Reindl KM.

Flaxseed consumption inhibits chemically-induced lung tumorigenesis and modulates expression of phase II enzymes and inflammatory cytokines in A/J mice.

Cancer Prev Res (Phila). 2017 Oct 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29074535

 

10

Miller BF, Hamilton KL, Majeed ZR, Abshire SM, Confides AL, Hayek AJ, Hunt ER, Shipman P, Peelor FF 3rd, Butterfield TA, Dupont-Versteegden EE.

Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non-massaged hind limb.

J Physiol. 2017 Oct 31. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29090454

Note: Hindlimb unloading study.

 

11

Stouth DW, Manta A, Ljubicic V.

Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity.

Am J Physiol Cell Physiol. 2017 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29092819

Note: Unilateral hindlimb denervation was used.

 

12

Heffner MA, Genetos DC, Christiansen BA.

Bone adaptation to mechanical loading in a mouse model of reduced peripheral sensory nerve function.

PLoS One. 2017 Oct 31;12(10):e0187354.

https://www.ncbi.nlm.nih.gov/pubmed/29088267

Note: Tibial compression loading was used. This article may be obtained online without charge.

 

13

James CR, Atkins LT, Yang HS, Dufek JS, Bates BT.

Prediction of calcaneal bone competence from biomechanical accommodation variables measured during weighted walking.

Hum Mov Sci. 2017 Oct 30;56(Pt B):37-45.

https://www.ncbi.nlm.nih.gov/pubmed/29096182

 

14

Morse A, Schindeler A, McDonald MM, Kneissel M, Kramer I, Little DG.

Sclerostin antibody augments the anabolic bone formation response in a mouse model of mechanical tibial loading.

J Bone Miner Res. 2017 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29090474

Note: Compression loading study.

 

15

Tiede-Lewis LM, Xie Y, Hulbert MA, Campos R, Dallas MR, Dusevich V, Bonewald LF, Dallas SL.

Degeneration of the osteocyte network in the C57BL/6 mouse model of aging.

Aging (Albany NY). 2017 Oct 9(10):2190-208.

https://www.ncbi.nlm.nih.gov/pubmed/29074822

Note: This article may be obtained online without charge.

 

16

Komova O, Krasavin E, Nasonova E, Mel'nikova L, Shmakova N, Cunha M, Testa E, Beuve M.

Relationship between radioadaptive response and individual radiosensitivity to low doses of gamma radiation: An extended study of chromosome damage in blood lymphocytes of three donors.

Int J Radiat Biol. 2017 Nov 2. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29095072

 

17

Horii A, Mitani K, Masumura C, Uno A, Imai T, Morita Y, Takahashi K, Kitahara T, Inohara H.

Hippocampal gene expression, serum cortisol level, and spatial memory in rats exposed to hypergravity.

J Vestib Res. 2017;27(4):209-15.

https://www.ncbi.nlm.nih.gov/pubmed/29081424

Note: Centrifugation was used.

 

18

Kalicinski M, Bock O, Schott N.

Motor imagery of body movements that can't be executed on Earth.

J Vestib Res. 2017;27(4):217-23.

https://www.ncbi.nlm.nih.gov/pubmed/29081428

Note: Motor imagery is suggested as an alternative to preflight immersion and parabolic training for astronauts. The Controllability of Motor Imagery Test is used to test subjects’ ability to imagine movements which are unfamiliar.

 

19

Myers ND, Park SE, Ahn S, Lee S, Sullivan PJ, Feltz DL.

Proposed sources of coaching efficacy: A meta-analysis.

J Sport Exerc Psychol. 2017 Oct 31. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29084461

 

20

Goswami N.

Falls and fall-prevention in older persons: Geriatrics meets spaceflight!

Front Physiol. 2017 Oct 11;8:603. Review.

https://www.ncbi.nlm.nih.gov/pubmed/29075195

Note: From the Introduction: "This paper outlines a general overview and comparison of spaceflight medicine, the experience of human aging, as well as important connections and parallels between spaceflight physiology and the aging process." This article may be obtained online without charge.

 

21

Pizzolato C, Lloyd DG, Barrett RS, Cook JL, Zheng MH, Besier TF, Saxby DJ.

Bioinspired technologies to connect musculoskeletal mechanobiology to the person for training and rehabilitation.

Front Comput Neurosci. 2017 Oct 18;11:96. Review.

https://www.ncbi.nlm.nih.gov/pubmed/29093676

Note: This article may be obtained online without charge.

 

22

Campos Filho AS, Novaes MA, Gomes AS.

The mental workload evaluation in visualizing telehealth indicators on three-dimensional interface.

Telemed J E Health. 2017 Oct 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29077532

Note: The NASA Task Load Index was used.

// end //

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