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NASA Spaceline Current Awareness List #781 12 January 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, January 12, 2018

SPACELINE Current Awareness Lists are distributed via listserv. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, rertwine@nasaprs.com.

 Papers deriving from NASA support:

1

Zanello SB, Tadigotla V, Hurley J, Skog J, Stevens B, Calvillo E, Bershad E.

Inflammatory gene expression signatures in idiopathic intracranial hypertension: Possible implications in microgravity-induced ICP elevation.

npj Microgravity. 2018 Jan 11;4(1):1.

https://www.nature.com/articles/s41526-017-0036-6

PI: S.B. Zanello

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This material is based upon work supported by the National Aeronautics and Space Administration under Grant/Contract/Agreement No NNX15AW48G to SZ."

 

2

Britten RA, Jewell JS, Duncan VD, Hadley MM, Macadat E, Musto AE, La Tessa C.

Impaired attentional set-shifting performance after exposure to 5 cGy of 600 MeV/n (28)Si particles.

Radiat Res. 2018 Jan 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29309264

PI: R.A. Britten

Journal Impact Factor: 2.539

Funding: "This work was funded by NASA (grant nos. NNX11AC56G and NNX14AE73G)."

 

3

Shuryak I, Loucas BD, Cornforth MN.

Straightening beta: Overdispersion of lethal chromosome aberrations following radiotherapeutic doses leads to terminal linearity in the alpha-beta model.

Front Oncol. 2017 Dec 21;7:318.

https://www.ncbi.nlm.nih.gov/pubmed/29312888

PIs: B. Loucas, M. Cornforth

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work supported by the following grants from the National Aeronautics and Space Administration (NASA): NNX15AG74G (MC) and NNX14AC76G (BL) and from the National Institute of Allergy and Infectious Diseases (NIAID): U19AI067773 (IS)."

 

4

Bhattacharya S, Asaithamby A.

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapy.

Transl Can Res. 2017 Jul;6 Suppl 5:S822-S839. Review.

http://tcr.amegroups.com/article/view/14117

PIs: A. Asaithamby, H. Sadek

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

Journal Impact Factor: 1.757

Funding: "The research in Asaithamby Aroumougame’s laboratory was partially supported by National Aeronautics and Space Administration (NNX13AD57G and NNX15AE06G), Cancer Prevention and Research Institute of Texas (RP160520), and National Institutes of Health (R01AG053341) grants."

 

5

Cornforth M, Shuryak I, Loucas B.

Lethal and nonlethal chromosome aberrations by gamma rays and heavy ions: A cytogenetic perspective on dose fractionation in hadron radiotherapy.

Transl Can Res. 2017 Jul;6 Suppl 5:S769-S778.

http://tcr.amegroups.com/article/view/13781

PIs: M. Cornforth, B. Loucas

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

Journal Impact Factor: 1.757

Funding: "This was work supported by the following grants from the National Aeronautics and Space Administration (NASA): NNX15AG74G (MC) and NNX14AC76G (BL)."

 

6

McKenna MJ, Bailey SM.

Chromosomal and telomeric biomarkers of normal tissue injury to evaluate risk of degenerative health effects (secondary malignancy, cardiovascular disease) post radiation therapy.

Transl Can Res. 2017 Jul;6 Suppl 5:S789-S794. Review.

http://tcr.amegroups.com/article/view/13853

PI: S.M. Bailey

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

Journal Impact Factor: 1.757

Funding: "Support from NASA (NNX14AB02G; NNX14AH51G) is gratefully acknowledged."

 

7

Ruttley TM, Robinson JA, Gerstenmaier WH.

The International Space Station: Collaboration, utilization, and commercialization.

Soc Sci Q. 2017 Dec;98(4):1160-74.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12469/abstract;jsessionid=3EFAFDB0163B33038DCB4C678AFC08AA.f04t01

Note: This article is part of the "Selling Space" Special Issue of Social Science Quarterly. For the remaining articles in the issue, please see the Other papers of interest section, citations 14-20.  This article may be obtained online without charge.

Journal Impact Factor:  0.849

Funding: No funding cited. T.M. Ruttley and J.A. Robinson are affiliated with NASA Johnson Space Center; W.H. Gerstenmaier is affiliated with NASA Headquarters.

 

8

Balaraj VS, Zeng PC, Sanford SP, McBride SA, Raghunandan A, Lopez JM, Hirsa AH.

Surface shear viscosity as a macroscopic probe of amyloid fibril formation at a fluid interface.

Soft Matter. 2017 Mar 1;13(9):1780-7.

https://www.ncbi.nlm.nih.gov/pubmed/28177017

PI: A.H. Hirsa

Journal Impact Factor: 3.889

Funding: "This work was supported by NASA grant NNX13AQ22G."

 

9

Olafson KN, Nguyen TQ, Rimer JD, Vekilov PG.

Antimalarials inhibit hematin crystallization by unique drug-surface site interactions.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7531-6.

https://www.ncbi.nlm.nih.gov/pubmed/28559329

PI: P.G. Vekilov

Journal Impact Factor: 9.661

Funding: "This work was supported by NIH through the Nanobiology Interdisciplinary Graduate Training Program of the Gulf Coast Consortia for Quantitative Biomedical Sciences (Grant T32EB009379) and directly (Grant 1R21AI126215-01), NASA (NNX14AD68G and NNX14AE79G), and The Welch Foundation (Grant E-1794)."

 

10

Safari MS, Poling-Skutvik R, Vekilov PG, Conrad JC.

Differential dynamic microscopy of bidisperse colloidal suspensions.

npj Microgravity. 2017 Aug 30;3:21.

https://www.ncbi.nlm.nih.gov/pubmed/28868354

PI: P.G. Vekilov

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA (NNX14AD68G to PGV and JCC), NSF (DMR-1151133, to JCC), and the Welch Foundation (E-1869, to JCC)."

 

11

Yamazaki T, Kimura Y, Vekilov PG, Furukawa E, Shirai M, Matsumoto H, Van Driessche AE, Tsukamoto K.

Two types of amorphous protein particles facilitate crystal nucleation.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2154-9.

https://www.ncbi.nlm.nih.gov/pubmed/28193873

PI: P.G. Vekilov

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.661

Funding: "This work was supported by the Tohoku University Global Center of Excellence Program for “Global Education and Research Center for Earth and Planetary Dynamics,” by Grants-in-Aid for Scientific Research for Research Activity Start-Up (26887001), for Young Scientists (A) (24684033) and for Scientific Research (S) (15H05731), and by the National Aeronautics and Space Administration (Grants NNX14AE79G and NNX14AD68G) and the National Science Foundation (Grant MCB-1518204). This work is partly supported by the Sasakawa Scientific Research grant from the Japan Science Society (28-232). The cryo-TEM observations were supported by the Nanotechnology Platform Program of the Ministry of Education, Culture, Sports, Science and Technology, Japan."

______________________________________________________

 

 

Other papers of interest:

 

1

Soga K, Wakabayashi K, Hoson T.

Growth and cortical microtubule dynamics in shoot organs under microgravity and hypergravity conditions.

Plant Signal Behav. 2017 Dec 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29286875

Note: ISS results. Centrifugation was used for hypergravity studies. From the title page: "Addendum to: Soga K, Yamazaki C, Kamada M, Tanigawa N, Kasahara H, Yano S, Kojo KH, Kutsuna N, Kato T, Hashimoto T, Kotake T, Wakabayashi K, Hoson T: Modification of growth anisotropy and cortical microtubule dynamics in Arabidopsis hypocotyls grown under microgravity conditions in space. Physiol Plant. 2018;162(1):xxx-xxx. doi:10.1111/ppl.12640." This citation appeared in SPACELINE Current Awareness List #765, 15 Dep 2017.

 

2

Ratushnyy AY, Buravkova LB.

Expression of focal adhesion genes in mesenchymal stem cells under simulated microgravity.

Dokl Biochem Biophys. 2017 Nov;477(1):354-6.

https://www.ncbi.nlm.nih.gov/pubmed/29297120

Note: A random positioning machine was used.

 

3

Zhang S, Wu Y, Weng Y, Xu Z, Chen W, Zheng D, Lin W, Liu J, Zhou Y.

In vitro growth of mouse preantral follicles under simulated microgravity.

J Vis Exp. 2017 Dec 17(130):55641.

https://www.ncbi.nlm.nih.gov/pubmed/29286463

Note: A Rotating Wall Vessel was used.

 

4

Fuchs FM, Raguse M, Fiebrandt M, Madela K, Awakowicz P, Laue M, Stapelmann K, Moeller R.

Investigating the detrimental effects of low pressure plasma sterilization on the survival of Bacillus subtilis spores using live cell microscopy.

J Vis Exp. 2017 Nov 30(129):56666.

https://www.ncbi.nlm.nih.gov/pubmed/29286386

 

5

Aryankalayil MJ, Chopra S, Levin J, Eke I, Makinde A, Das S, Shankavaram U, Vanpouille-Box C, Demaria S, Coleman CN.

Radiation-induced long noncoding RNAs in a mouse model after whole-body irradiation.

Radiat Res. 2018 Jan 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29309266

 

6

Raznitsyna I, Kulikova P, Rogatkin D, Kulikov D, Bychenkov O, Chursinova Y, Bobrov M, Glazkov A.

Fluorescence of radiation-induced tissue damage.

Int J Radiat Biol. 2018 Jan 3. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29297727

 

7

Rusin A, Seymour C, Mothersill C.

Chronic Fatigue and Immune Deficiency Syndrome (CFIDS), cellular metabolism, and ionizing radiation: A review of contemporary scientific literature and suggested directions for future research.

Int J Radiat Biol. 2018 Jan 3. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29297728

 

8

Castle KD, Chen M, Wisdom AJ, Kirsch DG.

Genetically engineered mouse models for studying radiation biology.

Transl Can Res. 2017 Jul;6 Suppl 5:S900-S913. Review.

http://tcr.amegroups.com/article/view/14112

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

 

9

Dörr W, Herrmann T, Trott K-R.

Normal tissue tolerance.

Transl Can Res. 2017 Jul;6 Suppl 5:S840-S851. Review.

http://tcr.amegroups.com/article/view/14602

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

 

10

Nickoloff JA, Boss M-K, Allen CP, LaRue SM.

Translational research in radiation-induced DNA damage signaling and repair.

Transl Can Res. 2017 Jul;6 Suppl 5:S875-S891. Review.

http://tcr.amegroups.com/article/view/14113

Note: This article is part of a supplement to Translational Cancer Research, "Focused Issue: Radiobiological Models Towards a Personalized Radiation Oncology," 2017 Jul; 6 Suppl 5. The articles in this supplement may be obtained online without charge at http://tcr.amegroups.com/issue/view/244.

11

Chen MM, Xu LH, Chang L, Yin P, Jiang ZL.

Reduction of motion sickness through targeting histamine N-methyltransferase in the dorsal vagal complex of the brain.

J Pharmacol Exp Ther. 2018 Jan 3. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29298819

Note: Rotation was used. This article may be obtained online without charge.

 

12

Peng HT, Bouak F, Wang W, Chow R, Vartanian O.

An improved model to predict performance under mental fatigue.

Ergonomics. 2018 Jan 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29297761

 

13

Harkey AF, Watkins J, Olex AL, DiNapoli KT, Lewis D, Binder B, Fetrow JS, Muday GK.

Identification of transcriptional and receptor networks that control root responses to ethylene.

Plant Physiol. 2017 Dec 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/29259106

Note: This article may be obtained online without charge.

 

Note: The following articles, as well as the article by Ruttley, et al. in the NASA section (#6), are part of the Special Issue, Selling Space, published in the December 2017 issue of Social Science Quarterly. From the Editor’s introduction: "The articles in this special issue focus on different aspects of selling science: What arguments does NASA use (or has used) to justify space exploration? Are different programs justified differently? How have these rationales changed over time? In part, our goal is to understand how NASA is able to sustain research programs given competition for federal funds—and to identify areas where it is unable to do so. Addressing these questions will show how the competition for funds shapes NASA's research priorities. But more generally, we believe that an understanding of NASA's abilities to sell science will help us make sense of the how the competition for funds shapes scientific research more generally." The issue is available at: http://onlinelibrary.wiley.com/doi/10.1111/ssqu.2017.98.issue-4/issuetoc. The articles may be obtained online without charge.

 

14

Bianco W, Gaddie K.

Special issue editors’ introduction: Selling space.

Soc Sci Q. 2017 Dec;98(4):1139-43.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12466/abstract

 

15

Bianco W, Gerhart D, Nicolson-Crotty S.

Waypoints for evaluating big science.

Soc Sci Q. 2017 Dec;98(4):1144-50.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12467/abstract

 

16

Bianco W, Schmidt E.

Knowing what we are getting: Evaluating scientific research on the International Space Station.

Soc Sci Q. 2017;98(4):1151-9.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12468/abstract

 

17

DeSante CD.

They chose to go to the Moon: How birth cohorts shape opinions on funding for space exploration.

Soc Sci Q. 2017 Dec;98(4):1175-88.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12470/abstract

 

18

Hayden JM, Geras MJ, Gerth NM, Crespin MH.

Land, wood, water, and space: Senator Robert S. Kerr, Congress, and selling the space race to the American public.

Soc Sci Q. 2017 Dec;98(4):1189-203.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12471/abstract

 

19

Alexander J.

Selling priorities in space science: The power of scientific community consensus.

Soc Sci Q. 2017;98(4):1204-15.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12472/abstract

 

20

Launius RD.

NASA's quest for human spaceflight popular appeal.

Soc Sci Q. 2017 Dec;98(4):1216-32.

http://onlinelibrary.wiley.com/doi/10.1111/ssqu.12473/abstract

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