NASA Spaceline Current Awareness List #787 23 February 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, February 23, 2018

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,

In case you missed it: Research by NASA-funded PI Elison Blancaflor was featured on the cover of the January 2018 issue of Journal of Cell Science, a Special Issue on Plant Cell Science. The Cover note says: "Root hairs are tip-growing cells that emerge from the surface of plant roots. By increasing the surface area of the root, root hairs play crucial roles in the uptake of water and nutrients from the soil. Phosphatidylinositol 4-phosphate (blue) is enriched at the apical-most dome of elongating root hairs and was found to recruit the ARF-GAP protein AGD1 to specific plasma membrane domains of root epidermal cells where new root hairs form. See article by Yoo et al. (" The image and note are available at

The article is: Yoo CM, Naramoto S, Sparks JA, Khan BR, Nakashima J, Fukuda H, Blancaflor EB. Deletion analysis of AGD1 reveals domains crucial for its plasma membrane recruitment and function in root hair polarity. J Cell Sci. 2018 Jan 29;131(2):jcs203828. Epub 2017 Jun 23. The citation appeared ahead of print in SPACELINE Current Awareness List #756 on Friday, July 7, 2017.

Papers deriving from NASA support:


Seuylemezian A, Vaishampayan P, Cooper K, Venkateswaran K.

Draft genome sequences of Acinetobacter and Bacillus strains isolated from spacecraft-associated surfaces.

Genome Announc. 2018 Feb 8;6(6):e1554-17.

Note: This article may be obtained online without charge.

Journal Impact Factor: 1.18

Funding: "The research described in this publication was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration."



Alabdulgader A, McCraty R, Atkinson M, Dobyns Y, Vainoras A, Ragulskis M, Stolc V.

Long-term study of heart rate variability responses to changes in the solar and geomagnetic environment.

Sci Rep. 2018 Feb 8;8(1):2663.

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.259

Funding: "This study was funded by King Abdulaziz City for Science and Technology, Saudi Arabia as part of larger initiative, HRV, VLF Power, Heart Coherence and long-term Clinical Outcomes in a Hypertensive Population Study number 36–1067." V. Stolc is affiliated with NASA Ames Research Center.



Fogle JD, Jannings AC, Gross MT, Scheuring RA, Crist J.

Concerns about ankle injury prophylaxis and acceptance of the parachute ankle brace among jumpmaster students.

Mil Med. 2018 Feb 6. [Epub ahead of print]

Note: This article may be obtained online without charge.

Journal Impact Factor: 0.906

Funding: No funding cited. R.A. Scheuring is affiliated with NASA Johnson Space Center.



Sylvester CB, Abe JI, Patel ZS, Grande-Allen KJ.

Radiation-induced cardiovascular disease: Mechanisms and importance of linear energy transfer.

Front Cardiovasc Med. 2018 Jan 31;5:5. Review.

PI: Z.S. Patel

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA grant NASA 13-13OMNI2-0032 to ZP and KG-A  and by a grant from the National Institute of Health (NIH) to J-IA (HL-130193, HL-123346, and HL-118462)."



Townsend LW, Adams JH, Blattnig SR, Clowdsley MS, Fry DJ, Jun I, McLeod CD, Minow JI, Moore DF, Norbury JW, Norman RB, Reames DV, Schwadron NA, Semones EJ, Singleterry RC, Slaba TC, Werneth CM, Xapsos MA.

Solar particle event storm shelter requirements for missions beyond low Earth orbit.

Life Sci Space Res. 2018 Feb 21. [Article in Press]

Journal Impact Factor: 1.97

Funding: No funding cited. J.H. Adams and J.I. Minow are affiliated with NASA Marshall Space Flight Center; S.R. Blattnig, M.S. Clowdsley, D.F. Moore, J.W. Norbury, R.B. Norman, R.C. Singleterry, T.C. Slaba, and C.M. Werneth are affiliated with NASA Langley Research Center; D.J. Fry, C.D. McLeod, and E.J. Semones are affiliated with NASA Johnson Space Center; I. Jun is affiliated with NASA Jet Propulsion Laboratory; M.A. Xapsos is affliated with NASA Goddard Space Flight Center.



Warner JE, Norman RB, Blattnig SR.

HZETRN radiation transport validation using balloon-based experimental data.

Life Sci Space Res. 2018 Feb 21. [Article in Press]

PI: J.W. Norbury

Journal Impact Factor: 1.97

Funding: "This work was supported by the Advanced Radiation Protection Project under the Game Changing Division of the Space Technology Mission Directorate and the Physics and Transport Project under the Human Research Program of the Human Exploration and Operations Mission Directorate of NASA."



Wang J, Bibra M, Venkateswaran K, Salem DR, Rathinam NK, Gadhamshetty V, Sani RK.

Biohydrogen production from space crew's waste simulants using thermophilic consolidated bioprocessing.

Bioresour Technol. 2018 Feb 4. [Epub ahead of print]

Journal Impact Factor: 5.651

Funding: "The authors gratefully acknowledge the financial support provided by National Aeronautics and Space Administration, Established Program to Stimulate Competitive Research, United States under award No. NNX13AB25A."




Other papers of interest:



Stucky F, Vesin JM, Kayser B, Uva B.

The effect of lower-body positive pressure on the cardiorespiratory response at rest and during submaximal running exercise.

Front Physiol. 2018 Jan 30;9:34.

Note: This article may be obtained online without charge.



Ratushnyy A, Ezdakova M, Yakubets D, Buravkova L.

Angiogenic activity of human adipose-derived mesenchymal stem cells under simulated microgravity.

Stem Cells Dev. 2018 Feb 12. [Epub ahead of print]

Note: A Random Positioning Machine was used. This article may be obtained online without charge.



Subramaniyan SA, Sheet S, Vinothkannan M, Yoo DJ, Lee YS, Belal SA, Shim KS.

One-pot facile synthesis of Pt nanoparticles using cultural filtrate of microgravity simulated grown P. chrysogenum and their activity on bacteria and cancer cells.

J Nanosci Nanotechnol. 2018 May 1;18(5):3110-25.

Note: The method of microgravity simulation is not identified in the available abstract.



Barravecchia I, De Cesari C, Pyankova OV, Scebba F, Mascherpa MC, Vecchione A, Tavanti A, Tedeschi L, Angeloni D.

Pitting corrosion within bioreactors for space cell-culture contaminated by Paenibacillus glucanolyticus, a case report.

Microgravity Sci Technol. 2018 Feb 21. [Article in Press]



Welch D, Buonanno M, Grilj V, Shuryak I, Crickmore C, Bigelow AW, Randers-Pehrson G, Johnson GW, Brenner DJ.

Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases.

Sci Rep. 2018 Feb 9;8(1):2752.

Note: This article may be obtained online without charge.



Iwamoto E, Bock JM, Casey DP.

Blunted shear-mediated dilation of the internal but not common carotid artery in response to lower body negative pressure.

J Appl Physiol (1985). 2018 Feb 15. [Epub ahead of print]



Ling S, Li Y, Zhong G, Zheng Y, Xu Q, Zhao D, Sun W, Jin X, Li H, Li J, Sun H, Cao D, Song J, Liu C, Yuan X, Wu X, Zhao Y, Liu Z, Li Q, Li Y.

Myocardial CKIP-1 overexpression protects from simulated microgravity-induced cardiac remodeling.

Front Physiol. 2018 Jan 25;9:40.

Note: Head-down tilt bed rest study. This article may be obtained online without charge.



Shen G, Link S, Kumar S, Nusbaum DM, Tse DY, Fu Y, Wu SM, Frankfort BJ.

Characterization of retinal ganglion cell and optic nerve phenotypes caused by sustained intracranial pressure elevation in mice.

Sci Rep. 2018 Feb 12;8(1):2856.

Note: This article may be obtained online without charge.



Zwaschka TA, Ahn JS, Cunitz BW, Bailey MR, Dunmire BL, Sorensen MD, Harper JD, Maxwell AD.

Combined burst wave lithotripsy and ultrasonic propulsion for improved urinary stone fragmentation.

J Endourol. 2018 Feb 13. [Epub ahead of print] 



Barreiro E.

Models of disuse muscle atrophy: Therapeutic implications in critically ill patients.

Ann Transl Med. 2018 Jan;6(2):29. Review.

Note: This article may be obtained online without charge.



Franchi MV, Ruoss S, Valdivieso P, Mitchell KW, Smith K, Atherton PJ, Narici MV, Flück M.

Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodeling of human skeletal muscle.

Acta Physiol (Oxf). 2018 Feb 13. [Epub ahead of print]



Šarabon N, Mekjavić IB, Eiken O, Babič J.

The effect of bed rest and hypoxic environment on postural balance and trunk automatic (re)actions in young healthy males.

Front Physiol. 2018 Jan 25;9:27.

Note: Bed rest study. This article may be obtained online without charge.



de Oliveira LC, de Oliveira RG, de Almeida Pires-Oliveira DA.

Effects of whole-body vibration versus Pilates exercise on bone mineral density in postmenopausal women: A randomized and controlled clinical trial.

J Geriatr Phys Ther. 2018 Feb 12. [Epub ahead of print]



Candéias SM, Kabacik S, Olsen AK, Eide DM, Brede DA, Bouffler S, Badie C.

Ionizing radiation does not impair the mechanisms controlling genetic stability during T cell receptor gene rearrangement in mice.

Int J Radiat Biol. 2018 Feb 12. [Epub ahead of print]



Jalili-Firoozinezhad S, Prantil-Baun R, Jiang A, Potla R, Mammoto T, Weaver JC, Ferrante TC, Kim HJ, Cabral JMS, Levy O, Ingber DE.

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip.

Cell Death Dis. 2018 Feb 14;9(2):223.

Note: This article may be obtained online without charge.



Smith SM, Limoli CL.

Stem cell therapies for the resolution of radiation injury to the brain.

Curr Stem Cell Rep. 2017 Dec;3(4):342-7. Review.



Sugihara T, Tanaka S, Braga-Tanaka I 3rd, Murano H, Nakamura-Murano M, Komura JI.

Screening of biomarkers for liver adenoma in low-dose-rate gamma-ray-irradiated mice.

Int J Radiat Biol. 2018 Feb 9. [Epub ahead of print]



Zalewski CK, Ackley RS, McCaslin DL, Clark MD, Hanks WD, Brewer CC.

Examination of utricular response using oVEMP and unilateral centrifugation rotation testing.

Ear Hear. 2018 Feb 10. [Epub ahead of print]

Note: Centrifugation was used.



Tian D, Mo F, Cai X, Miao Z, Xiao F, Chang Y, Wu L, Tang Y, Wang X, Ye C, Qian X, Gu W, Li M.

Acupuncture relieves motion sickness via the IRbeta-ERK1/2-dependent insulin receptor signalling pathway.

Acupunct Med. 2018 Feb 7. [Epub ahead of print]



Abeysuriya RG, Lockley SW, Robinson PA, Postnova S.

A unified model of melatonin, 6-sulfatoxymelatonin, and sleep dynamics.

J Pineal Res. 2018 Feb 13. [Epub ahead of print]



Chellappa SL, Morris CJ, Scheer F.

Daily circadian misalignment impairs human cognitive performance task-dependently.

Sci Rep. 2018 Feb 14;8(1):3041.

Note: This article may be obtained online without charge.



Tafforin C.

From human behavior to human factor in aerospace, astronautics and space operations.

SF J Aviat Aeronaut Sci. 2018 Jan-Mar;1(1):1003.

Note: This article may be obtained online without charge.



Komorowski M, Fleming S, Mawkin M, Hinkelbein J.

Anaesthesia in austere environments: Literature review and considerations for future space exploration missions.

npj Microgravity. 2018 Feb 23;4(1):5. Review.

Note: This article may be obtained online without charge.



Xu F, Wang C, Xiao K, Gao Y, Zhou T, Xu H.

Investigation of titanium dioxide/tungstic acid-based photocatalyst for human excrement wastewater treatment.

Acta Astronaut. 2018 Feb 17. [Article in Press]

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