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NASA Spaceline Current Awareness List #823 9 November 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, November 9, 2018

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Bigley AB, Agha NH, Baker FL, Spielmann G, Kunz HE, Mylabathula PL, Rooney B, Laughlin MS, Pierson DL, Mehta SK, Crucian BE, Simpson RJ.

NK-cell function is impaired during long-duration spaceflight.

J Appl Physiol (1985). 2018 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30382809

PIs: R.J. Simpson; B.E. Crucian; A.B. Bigley, NSBRI Postdoctoral Fellowship Program

Note: ISS results.

Journal Impact Factor: 3.256

Funding: "This work was supported by NASA grants NNX12AB48G, NNX16AB29G and NNX16AG02G to R.J. Simpson; a NASA Human Research Program grant to B.E. Crucian; and a National Space Biomedical Research Institute postdoctoral fellowship (NCC 9-58) to A.B. Bigley."

 

2

Blachowicz A, Venkateswaran K, Wang CCC.

Persistence of fungi in atypical, closed environments: Cultivation to omics.

In: Gurtler V, Trevors J, eds. Microbiology of Atypical Environments. Methods in Microbiology. Vol. 45. London: Academic Press, 2018. p. 67-86.

https://www.elsevier.com/books/microbiology-of-atypical-environment/trevors/978-0-12-814604-0

PI: C.C.C. Wang

Note: ISS results.

Journal Impact Factor: Not applicable to this publication

Funding: "We gratefully acknowledge NASA Space Biology grants #NNX15AB49G for supporting research in the laboratory of CCCW. Part of the research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration."

 

3

Yang J, Thornhill SG, Barrila J, Nickerson CA, Ott CM, McLean RJC.

Microbiology of the built environment in spacecraft used for human flight.

In: Gurtler V, Trevors J, eds. Microbiology of Atypical Environments. Methods in Microbiology. Vol. 45. London: Academic Press, 2018. p. 3-26.

https://www.elsevier.com/books/microbiology-of-atypical-environment/trevors/978-0-12-814604-0

PI: R.J. McLean

Note: ISS results.

Journal Impact Factor: Not applicable to this publication

Funding: "Work in the authors' laboratories is supported by a Grant from the National Aeronautics and Space Administration (NASA NNX17AC79G)."

 

4

Ochola DO, Sharif R, Bedford JS, Keefe TJ, Kato TA, Fallgren CM, Demant P, Costes SV, Weil MM.

Persistence of gamma-H2AX foci in bronchial cells correlates with susceptibility to radiation associated lung cancer in mice.

Radiat Res. 2018 Nov 6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30398394

PI: M.M. Weil

Journal Impact Factor: 2.531

Funding: "This work was supported by the U.S. Department of Energy (DOE grant no. DE-FG03-01ER63365 to JSB) and the National Aeronautics and Space Administration (NASA grant no. NNX15AK13G to MMW)."

 

5

Rosenberg MJ, Galvan-Garza RC, Clark TK, Sherwood DP, Young LR, Karmali F.

Human manual control precision depends on vestibular sensory precision and gravitational magnitude.

J Neurophysiol. 2018 Oct 31. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30379610

PIs: L.R. Young; T.K. Clark, NSBRI Postdoctoral Fellowship Program

Journal Impact Factor: 2.502

Funding: "This research was supported by the National Space Biomedical Research Institute through NASA NCC9-58 and by the National Institutes of Health through NIDCD DC013635 (FK)." PIs report funding under NCC 9-58-SA03401 (PI: Laurence Young), NCC 9-58-PF03502 (PI: Torin Clark), and NASA Space Technology Research Fellowship Grant #NNZ13AM68H (student: Raquel Galvan-Garza, advisor: Charles Oman).

 

6

Jones D, Gaewsky J, Saffarzadeh M, Putnam J, Weaver A, Somers J, Stitzel JD.

Multi-direction validation of a finite element 50th percentile male hybrid III anthropomorphic test device for spaceflight applications.

J Biomech Eng. 2018 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30383185

PI: J. Somers

Journal Impact Factor: 1.916

Funding: "This study was supported by NASA Human Health and Performance Contract (HHPC) through KBRwyle (NNJ15HK11B)." PI reports funding under NASA grant "ATD (Anthropomorphic Test Dummy) Injury Metric Sensitivity and Extensibility Study."

______________________________________________________

 

Other papers of interest:

 

1

Zhao X, Yu Y, Zhang X, Huang B, Bai P, Xu C, Li D, Zhang B, Liu C.

Decreased biofilm formation ability of Acinetobacter baumannii after spaceflight on China's Shenzhou 11 spacecraft.

Microbiologyopen. 2018 Oct 31. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30379419

Note: Shenzhou 11 results. This article may be obtained online without charge.

 

2

Montague TG, Almansoori A, Gleason EJ, Copeland DS, Foley K, Kraves S, Alvarez Saavedra E.

Gene expression studies using a miniaturized thermal cycler system on board the International Space Station.

PLoS One. 2018 Oct 31;13(10):e0205852.

https://www.ncbi.nlm.nih.gov/pubmed/30379894

Note: ISS results. Author Alia Almansoori is the winner of a 2017 Genes in Space United Arab Emirates (UAE) award to study protein expression changes in astronauts. The awards are for students in grades 7-8. This article may be obtained online without charge.

 

3

Shen M, Frishman WH.

Effects of spaceflight on cardiovascular physiology and health.

Cardiol Rev. 2018 Oct 25. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/30365406

Note: A number of spaceflight programs are mentioned in the review.

 

4

Yatagai F, Honma M, Dohmae N, Ishioka N.

Biological effects of space environmental factors: A possible interaction between space radiation and microgravity.

Life Sci Space Res. 2018 Nov 1. [Article in Press] Review.

http://www.sciencedirect.com/science/article/pii/S2214552418300695

Note: A number of spaceflight programs are mentioned in the review.

 

5

Chen B, Guo J, Wang S, Kang L, Deng Y, Li Y.

Simulated microgravity altered the metabolism of loureirin B and the expression of major cytochrome P450 in liver of rats.

Front Pharmacol. 2018 Oct 12;9:1130.

https://www.ncbi.nlm.nih.gov/pubmed/30369879

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

6

Olsson-Francis K, Ramkisson NK, Price AB, Slade DJ, Macey MC, Pearson VK.

The study of microbial survival in extraterrestrial environments using low Earth orbit and ground-based experiments.

In: Gurtler V, Trevors J, eds. Microbiology of Atypical Environments. Methods in Microbiology. Vol. 45. London: Academic Press, 2018. p. 27-65.

https://www.elsevier.com/books/microbiology-of-atypical-environment/trevors/978-0-12-814604-0

 

7

Zhang Y, Xin CX, Zhang LT, Deng YL, Wang X, Chen XY, Wang ZQ.

Detection of fungi from low-biomass spacecraft assembly clean room aerosols.

Astrobiology. 2018 Nov 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30383981

 

8

Chaillou T.

Skeletal muscle fiber type in hypoxia: Adaptation to high-altitude exposure and under conditions of pathological hypoxia.

Front Physiol. 2018 Oct 12;9:1450. Review.

https://www.ncbi.nlm.nih.gov/pubmed/30369887

Note: This article may be obtained online without charge.

 

9

Lipphaus A, Witzel U.

Biomechanical study of the development of long bones: Finite element structure synthesis of the human second proximal phalanx under growth conditions.

Anat Rec (Hoboken). 2018 Oct 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30369073

 

10

Iversen ES, McCarthy JM, Bell Burdett K, Lipton G, Phillips G, Dressman H, Ross J, Chao N.

Bridging the gaps: Using an NHP model to predict single dose radiation absorption in humans.

Int J Radiat Biol. 2018 Oct 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30371121

 

11

Avila E, Lakshminarasimhan KJ, DeAngelis GC, Angelaki DE.

Visual and vestibular selectivity for self-motion in macaque posterior parietal area 7a.

Cereb Cortex. 2018 Oct 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30365011

 

12

Bevelacqua JJ, Mortazavi SMJ.

Commentary regarding "On-orbit sleep problems of astronauts and countermeasures."

Mil Med Res. 2018 Oct 30;5(1):38.

https://www.ncbi.nlm.nih.gov/pubmed/30376883

Note: From the abstract: "This commentary addresses the article by Wu et al. entitled "On-orbit sleep problems of astronauts and countermeasures"." The original article appeared in SPACELINE Current Awareness List #802, 8 Jun 2018: Wu B, Wang Y, Wu X, Liu D, Xu D, Wang F. On-orbit sleep problems of astronauts and countermeasures. Mil Med Res. 2018 May 30;5(1):17. Review. https://www.ncbi.nlm.nih.gov/pubmed/29843821. Both articles may be obtained online without charge.

 

13

Novakovíc L, Guo T, Bacic A, Sampathkumar A, Johnson KL.

Hitting the wall-sensing and signaling pathways involved in plant cell wall remodeling in response to abiotic stress.

Plants (Basel). 2018 Oct 23;7(4):E89.

https://www.ncbi.nlm.nih.gov/pubmed/30360552

Note: This article may be obtained online without charge.

 

14

Zhang L, Ai W, Li T, Yu Q, Ji Y.

[Acclimation study of aerobic process for ersatz urine wastewater microbial treatment].

Space Med Med Eng. 2017;2017(5):369-73. Chinese.

http://caod.oriprobe.com/articles/52196336/Acclimation_Study_of_Aerobic_Process_for_Ersatz_Ur.htm

 

15

Shi L, Wang C, Nie J, Gu Y, Yu J, Wan Y, Tan Y.

[A split-pump-head DC motor driven micropump for space cell culture system].

Space Med Med Eng. 2017;2017(5):352-6. Chinese.

http://caod.oriprobe.com/articles/52196339/A_Split_pump_head_DC_Motor_Driven_Micropump_for_Sp.htm

 

16

Zhang L, Zhai G, Yan H, Guo J.

[Research on application of wearable capacitively-coupled electrode in ECG detection of manned spaceflight].

Space Med Med Eng. 2017;2017(5):357-62. Chinese.

http://caod.oriprobe.com/articles/52196334/Research_on_Application_of_Wearable_Capacitively_c.htm

 

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