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NASA Spaceline Current Awareness List #829 21 December 2018 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, December 21, 2018

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Please note: The next issue of SPACELINE Current Awareness (List #830) will be sent on January 4, 2019.

 

Papers deriving from NASA support:

 

1

Romsdahl J, Blachowicz A, Chiang AJ, Chiang YM, Masonjones S, Yaegashi J, Countryman S, Karouia F, Kalkum M, Stajich JE, Venkateswaran K, Wang CCC.

International Space Station conditions alter genomics, proteomics, and metabolomics in Aspergillus nidulans.

Appl Microbiol Biotechnol. 2018 Dec 12. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30539259

PI: K. Venkateswaran

Note: ISS results.

Journal Impact Factor: 3.34

Funding: "This research was funded by a 2012 Space Biology NNH12ZTT001N grant nos. 19-12829-26 under Task Order NNN13D111T awarded to CW and KV, which also funded JR and AB."

 

2

Talburt ED, French AJ, Lopez DK, Polo S-HL, Boyko V, Dinh MT, Rask JC, Stewart HJ, Chakravarty K.

Temporal RNA integrity analysis of archived spaceflight biological samples.

Gravit Space Res. 2018 Dec;6(2):44-53.

http://gravitationalandspacebiology.org/index.php/journal/article/view/822

Note: ISS and Spacelab Life Sciences 1 (SLS-1), Commercial Biomedical Test Module 3 (CBTM-3), Rodent Research 1 (RR1), and Rodent Research 3 (RR3) results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "E.D.T. acknowledges support from H.J.S. and the NASA Volunteer Internship Program." E.D. Talburt, A.J. French, D.K. Lopez, S-H.L. Polo, V. Boyko, M.T. Dinh, J.C. Rask, and H.J. Stewart are affiliated with NASA Ames Research Center.

 

3

Ozdemir RA, Goel R, Reschke MF, Wood SJ, Paloski WH.

Critical role of somatosensation in postural control following spaceflight: Vestibularly deficient astronauts are not able to maintain upright stance during compromised somatosensation.

Front Physiol. 2018 Nov 27;9:1680.

https://www.ncbi.nlm.nih.gov/pubmed/30538640

Note: Space Shuttle results. This article may be obtained online without charge.

Journal Impact Factor: 3.394

Funding: No funding cited. M.F. Reschke, S.J. Wood, and W.H. Paloski are affiliated with NASA Johnson Space Center.

 

4

Duscher AA, Conesa A, Bishop M, Vroom MM, Zubizarreta SD, Foster JS.

Transcriptional profiling of the mutualistic bacterium Vibrio fischeri and an hfq mutant under modeled microgravity.

npj Microgravity. 2018 Dec 18;4(1):25.

https://www.nature.com/articles/s41526-018-0060-1

PI: J.S. Foster

Note: High aspect ratio rotating vessels (HARVs) were used. This article may be obtained online without charge.

Journal Impact Factor: 2.00

Funding: "This work was supported in part by the NASA Space Biology program (NNX13AM44G) and Florida Space Institute Space Research Initiative awarded to J.S.F. A.A.D. was supported in part by a Dissertation Improvement Fellowship from the NASA Florida Space Grant Consortium. S.D.Z. was supported by a National Science Foundation STEP award (DUE 1161177). M.B. and M.M.V. were supported by a NASA Florida Space Grant Consortium Scholarship award."

 

5

Herron MD, Zamani-Dahaj SA, Ratcliff WC.

Trait heritability in major transitions.

BMC Biol. 2018 Dec 13;16(1):145.

https://www.ncbi.nlm.nih.gov/pubmed/30545356

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.77

Funding: "This work was supported by grants from NASA (NNA17BB05A, NNX15AR33G), NSF (DEB-1457701, DEB-1723293, DEB-1456652), and the John Templeton Foundation (43285)."

 

6

Bokhari RS, Metzger CE, Allen MR, Bloomfield SA.

Daily acute bouts of weight-bearing during hindlimb unloading mitigate disuse-induced deficits in cancellous bone.

Gravit Space Res. 2018 Dec;6(2):2-11.

http://gravitationalandspacebiology.org/index.php/journal/article/view/808

PI: S.A. Bloomfield

Note: Hindlimb unloading study. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA Space Biology award #NNX13AL25G."

 

7

Shuryak I, Brenner DJ.

Mechanistic modeling predicts no significant dose rate effect on heavy-ion carcinogenesis at dose rates relevant for space exploration.

Radiat Prot Dosimetry. 2018 Dec 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30535099

PIs: P. Grabham; A.J. Fornace/D.J. Brenner/NSCOR

Journal Impact Factor: 0.822

Funding: "This research was supported by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) grant 5P41EB002033-22, the National Institute of Allergy and Infectious Diseases (NIAID) grant 5U19AI067773-13, and by National Aeronautics and Space Administration grants NNX15AI21G and NNX14AR22G."

 

8

Clebone A, Strupp KM, Whitney G, Anderson MR, Hottle J, Fehr J, Yaster M, Schleelein LE, Burian BK, Galvez JA, Lockman JL, Polaner D, Barnett NR, Keane MJ, Manikappa S, Gleich S, Greenberg RS, Vincent A, Oswald SL, Starks R, Licata S. 

Development and usability testing of the society for pediatric anesthesia Pedi Crisis mobile application.

Anesth Analg. 2018 Dec 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30540613

Journal Impact Factor: 3.463

Funding: No funding cited. B.K. Burian is affiliated with NASA Ames Research Center.

 

9

Califar B, Tucker R, Cromie J, Sng N, Schmitz RA, Callaham JA, Barbazuk B, Paul A-L, Ferl RJ.

Approaches for surveying cosmic radiation damage in large populations of Arabidopsis thaliana seeds – Antarctic balloons and particle beams. 

Gravit Space Res. 2018 Dec;6(2):54-73.

http://gravitationalandspacebiology.org/index.php/journal/article/view/824

Note: Balloon flight. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was conducted with funding derived from University of Florida resources and the donated effort of many people and organizations." NASA grants and contracts cited are: NASA Florida Space Grant Consortium (NNX15_011) and NASA Space Act Agreement KCA-4572-1. NASA programs cited are: NASA Balloon Payload Office (BPO) and NASA Space Radiation Laboratory (NSRL).

 

10

Christenson D, Sevanthi R, Morse A, Jackson A.

Assessment of membrane-aerated biological reactors (MABRs) for integration into space-based water recycling system architectures.

Gravit Space Res. 2018 Dec;6(2):12-27.

http://gravitationalandspacebiology.org/index.php/journal/article/view/770

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA grant NNX13AL52H and NASA cooperative agreement NNX12AK45A in support of development of the Alternative Water Processor (AWP) technology, a technology element of the Next Generation Life Support Project, Game Changing Development Program, Space Technology Mission Directorate."

 

11

Gaffney CJ, Pollard AK, Deane CS, Cooke M, Balsamo M, Hewitt J, Vanapalli SA, Szewczyk NJ, Etheridge T, Phillips BE.

Worms in space for outreach on Earth: Space life science activities for the classroom.

Gravit Space Res. 2018 Dec;6(2):74-82.

http://gravitationalandspacebiology.org/index.php/journal/article/view/814

PI: S.A. Vanapalli

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by the BBSRC (grant numbers BB/N015894/1 and BB/P025781/1), the UK Space Agency, the STFC (grant number ST/R005737), and ESA (designations Molecular Muscle Experiment and ESA-14-ISLRA_Prop-0029). JH and SAV were supported by NASA (NASA NNX15AL16G)."

______________________________________________________

 

Other papers of interest:

 

1

Kopp S, Krüger M, Bauer J, Wehland M, Corydon TJ, Sahana J, Nassef MZ, Melnik D, Bauer TJ, Schulz H, Schütte A, Schmitz B, Oltmann H, Feldmann S, Infanger M, Grimm D.

Microgravity affects thyroid cancer cells during the TEXUS-53 Mission stronger than hypergravity.

Int J Mol Sci. 2018 Dec 12;19(12):4001.

https://www.ncbi.nlm.nih.gov/pubmed/30545079

Note: TEXUS-53 results. This article may be obtained online without charge.

 

2

Goswami N, Blaber AP, Hinghofer-Szalkay H, Convertino VA.

Lower body negative pressure: Physiological effects, applications, and implementation.

Physiol Rev. 2019 Jan 1;99(1):807-51. Review.

https://www.ncbi.nlm.nih.gov/pubmed/30540225

Note: The use of LBNP during spaceflight is discussed.

 

3

Oliver SR, Anderson KJ, Hunstiger MM, Andrews MT.

Turning down the heat: Down-regulation of sarcolipin in a hibernating mammal.

Neurosci Lett. 2019 Mar 23;696:13-9. Review. Epub 2018 Dec 5.

https://www.ncbi.nlm.nih.gov/pubmed/30528880

 

4

Sheet S, Sathishkumar Y, Choi MS, Lee YS.

Insight into Pseudomonas aeruginosa pyocyanin production under low-shear modeled microgravity.

Bioprocess Biosyst Eng. 2018 Dec 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30535586

Note: A high aspect ratio vessel (HARV) was used.

 

5

Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM.

Irisin mediates effects on bone and fat via ɑV integrin receptors.

Cell. 2018 Dec 13;175(7):1756-68.e17.

https://www.ncbi.nlm.nih.gov/pubmed/30550785

Note: This article may be obtained online without charge.

 

6

Marzuca-Nassr GN, Vitzel KF, Murata GM, Márquez JL, Curi R.

Experimental model of hindlimb suspension-induced skeletal muscle atrophy in rodents.

Methods Mol Biol. 2019;1916:167-76. Epub 2018 Dec 11.

https://www.ncbi.nlm.nih.gov/pubmed/30535694

Note: Hindlimb unloading study.

 

7

Murphy EK, Skinner J, Martucci M, Rutkove SB, Halter RJ.

Towards electrical impedance tomography coupled ultrasound imaging for assessing muscle health.

IEEE Trans Med Imaging. 2018 Dec 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30530320

 

8

Chandra A, Park SS, Pignolo RJ.

Potential role of senescence in radiation-induced damage of the aged skeleton.

Bone. 2019 Mar;120:423-31. Epub 2018 Dec 10.

https://www.ncbi.nlm.nih.gov/pubmed/30543989

 

9

Friedman MA, Zhang Y, Wayne JS, Farber CR, Donahue HJ.

Single limb immobilization model for bone loss from unloading.

J Biomech. 2018 Dec 5. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30551918

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

10

Wissmann F, Klages T.

A simple method to monitor the dose rate of secondary cosmic radiation at altitude.

J Radiol Prot. 2019 Mar;39(1):71-84. Epub 2018 Nov 6.

https://www.ncbi.nlm.nih.gov/pubmed/30524002

 

11

Cheng Z, Gu Y.

Vestibular system and self-motion.

Front Cell Neurosci. 2018 Nov 22;12:456. Review.

https://www.ncbi.nlm.nih.gov/pubmed/30524247

Note: This article may be obtained online without charge.

 

12

Qi R, Su Y, Pan L, Mao Y, Liang L, Dai Z, Wang J, Cai Y.

Anti-cholinergics mecamylamine and scopolamine alleviate motion sickness-induced gastrointestinal symptoms through both peripheral and central actions.

Neuropharmacology. 2019 Mar 1;146:252-63. Epub 2018 Dec 14.

https://www.ncbi.nlm.nih.gov/pubmed/30543811

 

13

Kato T, Yanagida R, Takko C, Kurazumi T, Inoue N, Suzuki G, Ogawa Y, Furukawa S, Iwasaki KI.

Dynamic cerebral autoregulation after confinement in an isolated environment for 14 days.

Environ Health Prev Med. 2018 Dec 6;23(1):61.

https://www.ncbi.nlm.nih.gov/pubmed/30522430

Note: The study was conducted at the "Confinement Environment Adaptation Training Facility" in Tsukuba Space Center, Japan. This article may be obtained online without charge.

 

14

Smith SM, Krajbich I.

Gaze amplifies value in decision making.

Psychol Sci. 2018 Dec 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30526339

 

15

Renna L, Stefano G, Slabaugh E, Wormsbaecher C, Sulpizio A, Zienkiewicz K, Brandizzi F.

TGNap1 is required for microtubule-dependent homeostasis of a subpopulation of the plant trans-Golgi network.

Nat Commun. 2018 Dec 14;9(1):5313.

https://www.ncbi.nlm.nih.gov/pubmed/30552321

Note: This article may be obtained online without charge.

 

16

Wang J, Wang J, Li W, Luo G, Yang S, Du Y, Wei W, Jin W, Luo S, Li X.

Photosynthetic response of Scenedesmus quadricauda to carbon ions irradiation.

Acta Astronaut. 2018 Dec 10. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S009457651830537X

 

17

Manyapu KK, Peltz L, De Leon P.

Self-cleaning spacesuits for future planetary missions using carbon nanotube technology.

Acta Astronaut. 2018 Dec 15. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576517318210

 

18

Wang SK, Wang K, Zhou YL, Yan B, Li X, Zhang Y, Wu WB, Wang AP.

Development of the varying gravity rack (VGR) for the Chinese Space Station.

Microgravity Sci Technol. 2018 Dec 19. [Article in Press]

https://link.springer.com/article/10.1007%2Fs12217-018-9670-1

Note: From the abstract: "The VGR has two centrifuges with diameters of 900 mm and can provide the gravity range from 0.01 g to 2 g."

 

19

Bakhsh A, Martin GFJ, Bicknell CD, Pettengell C, Riga C.

An evaluation of the impact of high-fidelity endovascular simulation on surgeon stress and technical performance.

J Surg Educ. 2018 Dec 6. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30527702

Note: The NASA Task Load Index was used.

 

20

Jiang M, Liu S, Gao J, Feng Q, Zhang Q.

Comprehensive evaluation of user interface for ventilators based on respiratory therapists' performance, workload, and user experience.

Med Sci Monit. 2018 Dec 15;24:9090-101.

https://www.ncbi.nlm.nih.gov/pubmed/30552313

Note: The NASA Task Load Index was used.

 

21

Sreejith SG.

The fallen envoy: The rise and fall of astronaut in International Space Law.

Space Policy. 2018 Dec 7. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0265964618300614

Note: From the abstract: "This article revisits the legal status of astronauts by recounting the tale of their rise and fall in the International Space Law (ISL)."

...

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