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NASA Spaceline Current Awareness List #830 $ January 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, January 4, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Hammond TG, Allen PL, Birdsall HH.

Effects of space flight on mouse liver versus kidney: Gene pathway analyses.

Int J Mol Sci. 2018 Dec 18;19(12):E4106.

https://www.ncbi.nlm.nih.gov/pubmed/30567358

PI: T.G. Hammond

Note: STS-108 results. This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: "NASA Grants NNX13AN32G, NNX12AM93G, and NNX10AP01G supported these studies."

 

2

Mao XW, Sandberg LB, Gridley DS, Herrmann EC, Zhang G, Raghavan R, Zubarev RA, Zhang B, Stodieck LS, Ferguson VL, Bateman TA, Pecaut MJ.

Proteomic analysis of mouse brain subjected to spaceflight.

Int J Mol Sci. 2018 Dec 20;20(1):E7.

https://www.ncbi.nlm.nih.gov/pubmed/30577490

PI: M.J. Pecaut

Note: STS-135 results. This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: "This study was supported by NASA managed cooperative agreement NNX10AJ31G, NASA Grant NNX13AN34G, and the LLUMC Departments of Biomedical Engineering Sciences and Radiation Medicine."

 

3

Charles JB, Pietrzyk RA.

A year on the International Space Station: Implementing a long-duration biomedical research mission.

Aerosp Med Hum Perform. 2019 Jan 1;90(1):4-11.

https://www.ncbi.nlm.nih.gov/pubmed/30579371

Note: ISS results.

Journal Impact Factor: 0.899

Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.

 

4

Ozawa K, Packwood W, Varlamov O, Qi Y, Xie A, Wu MD, Ruggeri Z, López JA, Lindner JR.

Molecular imaging of VWF (von Willebrand Factor) and platelet adhesion in postischemic impaired microvascular reflow.

Circ Cardiovasc Imaging. 2018 Nov;11(11):e007913.

https://www.ncbi.nlm.nih.gov/pubmed/30571316

PI: J.R. Lindner

Note: This article may be obtained online without charge.

Journal Impact Factor: 6.221

Funding: "Dr Ozawa is supported by a grant from Manpei Suzuki Diabetes Foundation. Dr Lindner is supported by grants R01-HL078610 and R01-HL130046 from the National Institutes of Health (NIH) and a grant (14-14NSBRI1-0025) from the National Aeronautics and Space Administration (NASA) National Space Biomedical Research Institute. Dr López is supported by R01-HL091153 and R01-HL11763 from the NIH. The microscopy core is supported by grant S10-RR024585 from the NIH."

 

5

Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A.

Increased chromosome aberrations in cells exposed simultaneously to simulated microgravity and radiation.

Int J Mol Sci. 2018 Dec 22;20(1):E43.

https://www.ncbi.nlm.nih.gov/pubmed/30583489

PI: M. Hada

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: "This work was supported by NASA Space Biology Program (80NSSC19K0133) (M.H., K.F. and A.T.), TAMU Chancellor’s Research Initiative, Texas A&M University (P.B.S.), a MEXT Grant-in-Aid for Scientific Research on Innovative Areas, Japan (JP15H05945, JP15H05935, and JP15K21745) (A.T.), “Living in Space”, Research Projects with Heavy Ions at the Gunma University Heavy Ion Medical Center (GHMC) (A.T.), and the Gunma University Initiative for Advanced Research (GIAR) (H.I and K.D.H.). Funding for I.P. was provided by the NASA Human Health and Performance Contract (HHPC) number NNJ15HK11B."

 

6

Narayanan SA, Ford J, Zawieja DC.

Impairment of lymphatic endothelial barrier function by X-ray irradiation.

Int J Radiat Biol. 2018 Dec 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30570385

Journal Impact Factor: 1.97

Funding: "This work was funded by NIH (Grant: U01HL123420). SAN was supported by the NASA-National Space Biomedical Research Institute Predoctoral Fellowship via NASA Cooperative Agreement NCC 9-58."

 

7

Dinges DF, Basner M, Ecker AJ, Baskin P, Johnston S.

Effects of zolpidem and zaleplon on cognitive performance after emergent Tmax and morning awakenings: A randomized placebo-controlled trial.

Sleep. 2018 Dec 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30576525

PIs: S. Johnston, D.F. Dinges

Journal Impact Factor: 5.135

Funding: "This study was funded by the National Aeronautics and Space Administration (NASA) through grant NNX09AE24G."

_______________________________________________________

 

 

Other papers of interest:

 

1

Bilancio G, Cavallo P, Lombardi C, Guarino E, Cozza V, Giordano F, Cirillo M.

Urea and minerals monitoring in space missions by spot samples of saliva and urine.

Aerosp Med Hum Perform. 2019 Jan 1;90(1):43-7.

https://www.ncbi.nlm.nih.gov/pubmed/30579377

Note: ISS results.

 

2

Koryak YA.

Architectural and functional specifics of the human triceps surae muscle in vivo and its adaptation to microgravity.

J Appl Physiol (1985). 2018 Dec 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30571290

Note: ISS results.

 

3

Kordyum E, Chapman D, Brykov V.

Plant cell development and aging may accelerate in microgravity.

Acta Astronaut. 2018 Dec 28. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576518304752

Note: Spaceflight and clinorotation results are discussed.

 

4

Choukèr A, Bereiter-Hahn J, Singer D, Heldmaier G.

Hibernating astronauts-science or fiction?

Pflugers Arch. 2018 Dec 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30569200

Note: This article may be obtained online without charge.

 

5

Li Y, Cao L, Li J, Sun Z, Liu C, Liang H, Wang D, Tian J.

Influence of microgravity-induced intervertebral disc degeneration of rats on expression levels of p53/p16 and proinflammatory factors.

Exp Ther Med. 2019 Feb;17(2):1367-73.

https://www.spandidos-publications.com/10.3892/etm.2018.7085

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

6

Piotrowski T, Rittweger J, Zange J.

A comparison of squatting exercise on a centrifuge and with earth gravity.

Front Physiol. 2018 Dec 5;9:1759.

https://www.ncbi.nlm.nih.gov/pubmed/30568604

Note: A centrifuge was used. This article may be obtained online without charge.

 

7

Ritzmann R, Freyler K, Kümmel J, Gruber M, Belavy DL, Felsenberg D, Gollhofer A, Kramer A, Ambrecht G.

High intensity jump exercise preserves posture control, gait, and functional mobility during 60 days of bed-rest: An RCT including 90 days of follow-up.

Front Physiol. 2018 Dec 3;9:1713.

https://www.ncbi.nlm.nih.gov/pubmed/30559676

Note: Bed rest study. This article may be obtained online without charge.

 

8

Lerner DJ, Chima RS, Patel K, Parmet AJ.

Ultrasound guided lumbar puncture and remote guidance for potential in-flight evaluation of VIIP/SANS.

Aerosp Med Hum Perform. 2019 Jan 1;90(1):58-62.

https://www.ncbi.nlm.nih.gov/pubmed/30579380

 

9

Bemben D, Stark C, Taiar R, Bernardo-Filho M.

Relevance of whole-body vibration exercises on muscle strength/power and bone of elderly individuals.

Dose Response. 2018 Oct-Dec;16(4):1559325818813066.

https://www.ncbi.nlm.nih.gov/pubmed/30559636

Note: This article may be obtained online without charge.

 

10

Jeong SM, Seo BK, Park YC, Baek YH.

A review of complementary and alternative medicine therapies on muscular atrophy: A literature review of in vivo/in vitro studies.

Evid Based Complement Alternat Med. 2018 Dec 26;2018:8654719. Review.

https://www.ncbi.nlm.nih.gov/pubmed/30581489

Note: This article may be obtained online without charge.

 

11

Malis V, Sinha U, Csapo R, Narici M, Smitaman E, Sinha S.

Diffusion tensor imaging and diffusion modeling: Application to monitoring changes in the medial gastrocnemius in disuse atrophy induced by unilateral limb suspension.

J Magn Reson Imaging. 2018 Dec 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30569482

Note: Hindlimb unloading study.

 

12

Pietrangelo L, Michelucci A, Ambrogini P, Sartini S, Guarnier FA, Fusella A, Zamparo I, Mammucari C, Protasi F, Boncompagni S.

Muscle activity prevents the uncoupling of mitochondria from Ca2+ release units induced by ageing and disuse.

Arch Biochem Biophys. 2018 Dec 20;663:22-33.

https://www.ncbi.nlm.nih.gov/pubmed/30578752

 

13

Theilen NT, Jeremic N, Weber GJ, Tyagi SC.

TFAM overexpression diminishes skeletal muscle atrophy after hindlimb suspension in mice.

Arch Biochem Biophys. 2018 Dec 13. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30553768

Note: Hindlimb unloading study.

 

14

Wang QQ, Jing XM, Bi YZ, Cao XF, Wang YZ, Li YX, Qiao BJ, Chen Y, Hao YL, Hu J.

Human umbilical cord Wharton's jelly derived mesenchymal stromal cells may attenuate sarcopenia in aged mice induced by hindlimb suspension.

Med Sci Monit. 2018 Dec 20;24:9272-81.

https://www.ncbi.nlm.nih.gov/pubmed/30571669

Note: Hindlimb unloading study.

 

15

Aykin-Burns N, Pathak R, Boerma M, Kim T, Hauer-Jensen M.

Utilization of vitamin E analogs to protect normal tissues while enhancing antitumor effects.

Semin Radiat Oncol. 2019 Jan;29(1):55-61.

https://www.ncbi.nlm.nih.gov/pubmed/30573184

Note: This article may be obtained online without charge.

 

16

Cucinotta FA, Cacao E, Kim MY, Saganti PB.

Non-targeted effects lead to a paradigm shift in risk assessment for a mission to the Earth's moon or Martian moon Phobos.

Radiat Prot Dosimetry. 2018 Dec 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30576527

 

17

Cucinotta FA, Cacao E, Alp M.

Detriments in neuron morphology following heavy ion irradiation: What's the target?

Radiat Prot Dosimetry. 2018 Dec 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30561664

 

18

Czub J, Banaś D, Braziewicz J, Buraczewska I, Jaskóla M, Kaźmierczak U, Korman A, Lankoff A, Lisowska H, Szefliński Z, Wojewódzka M, Wójcik A.

Biological effects of mixed-ion beams. Part 1: Effect of irradiation of the CHO-K1 cells with a mixed-ion beam containing the carbon and oxygen ions.

Appl Radiat Isot. 2018 Sep;139:304-9.

https://www.ncbi.nlm.nih.gov/pubmed/29883949

 

19

Czub J, Banaś D, Braziewicz J, Buraczewska I, Jaskóla M, Kaźmierczak U, Korman A, Lankoff A, Lisowska H, Szefliński Z, Wojewódzka M, Wójcik A.

Biological effects of mixed-ion beams. Part 2: The relative biological effectiveness of CHO-K1 cells irradiated by mixed- and single-ion beams.

Appl Radiat Isot. 2018 Dec 5. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30553541

 

20

Ewing LE, Miousse IR, Pathak R, Skinner CM, Kosanke S, Boerma M, Hauer-Jensen M, Koturbash I.

NZO/HlLtJ as a novel model for the studies on the role of metabolic syndrome in acute radiation toxicity.

Int J Radiat Biol. 2018 Dec 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30561233

 

21

Fish BL, MacVittie TJ, Szabo A, Moulder JE, Medhora M.

WAG/RijCmcr rat models for injuries to multiple organs by single high dose ionizing radiation: Similarities to non-human primates (NHP).

Int J Radiat Biol. 2018 Dec 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30575429

 

22

Miura S, Yamaguchi M, Yoshino H, Nakai Y, Kashiwakura I.

Dose-dependent increase of Nrf2 target gene expression in mice exposed to ionizing radiation.

Radiat Res. 2018 Dec 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30566388

 

23

Wu A, Hu W, Zhang J, Guo Z, Liu C, Katsube T, Tanaka K, Nie J, Wang B, Zhou G.

Mouse intestinal Lgr5+ stem cells are more sensitive to heavy ion irradiation than Bmi1+ stem cells.

Acta Biochim Biophys Sin (Shanghai). 2018 Dec 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30566572

 

24

Asawavichienjinda T, Patarapak S.

Reliability of the Thai Version of the Motion Sickness Susceptibility Questionnaire Short-Form.

Aerosp Med Hum Perform. 2019 Jan 1;90(1):26-31.

https://www.ncbi.nlm.nih.gov/pubmed/30579374

 

25

Kim M, Maguire EA.

Encoding of 3D head direction information in the human brain.

Hippocampus. 2018 Dec 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30561118

Note: This article may be obtained online without charge.

 

26

Campbell MR.

History of the Health Maintenance Facility for Space Station Freedom.

Aerosp Med Hum Perform. 2019 Jan 1;90(1):65-7.

https://www.ncbi.nlm.nih.gov/pubmed/30579382

 

27

Cui Y, Cao W, He Y, Zhao Q, Wakazaki M, Zhuang X, Gao J, Zeng Y, Gao C, Ding Y, Wong HY, Wong WS, Lam HK, Wang P, Ueda T, Rojas-Pierce M, Toyooka K, Kang BH, Jiang L.

A whole-cell electron tomography model of vacuole biogenesis in Arabidopsis root cells.

Nat Plants. 2018 Dec 17. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30559414

 

28

Ichida H, Morita R, Shirakawa Y, Hayashi Y, Abe T.

Targeted exome sequencing of unselected heavy-ion beam-irradiated populations reveals less-biased mutation characteristics in the rice genome.

Plant J. 2018 Dec 25. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30584677

 

29

Kryvokhyzha MV, Krutovsky KV, Rashydov NM.

Differential expression of flowering genes in Arabidopsis thaliana under chronic and acute ionizing radiation.

Int J Radiat Biol. 2018 Dec 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30570374

 

30

Yuan P, Yang T, Poovaiah BW.

Calcium signaling-mediated plant response to cold stress.

Int J Mol Sci. 2018 Dec 5;19(12):E3896.

https://www.ncbi.nlm.nih.gov/pubmed/30563125

Note: This article may be obtained online without charge.

 

31

Amalfitano S, Levantesi C, Garrelly L, Giacosa D, Bersani F, Rossetti S.

Water quality and total microbial load: A double-threshold identification procedure intended for space applications.

Front Microbiol. 2018 Dec 6;9:2903.

https://www.ncbi.nlm.nih.gov/pubmed/30574126

Note: This article may be obtained online without charge.

 

32

Arena C, Vitale E, Hay Mele B, Cataletto PR, Turano M, Simoniello P, De Micco V.

Suitability of Solanum lycopersicum L. 'Microtom' to be grown in bioregenerative life support systems: Exploring the effect of high-LET ionising radiation on photosynthesis, leaf structure and fruit traits.

Plant Biol (Stuttg). 2018 Dec 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30585676

 

33

Tikhomirova NA, Trifonov SV, Ushakova SA, Morozov EA, Anischenko OV, Tikhomirov AA.

Incorporation of mineralized human waste and fish waste as a source of higher plant mineral nutrition in the BTLSS mass exchange.

Life Sci Space Res. 2018 Dec 27. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552418300336

 

34

Hosseini M, Faiola A, Jones J, Vreeman DJ, Wu H, Dixon BE.

Impact of document consolidation on healthcare providers' perceived workload and information reconciliation tasks: A mixed methods study.

J Am Med Inform Assoc. 2018 Dec 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30566630

Note: The NASA Task Load Index was used.

// end //

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