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NASA Spaceline Current Awareness List #832 18 January 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, January 18, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

Papers deriving from NASA support:

 

1

Beheshti A, Shirazi-Fard Y, Choi S, Berrios D, Gebre SG, Galazka JM, Costes SV.

Exploring the effects of spaceflight on mouse physiology using the open access NASA GeneLab Platform.

JoVE. 2018 Dec(143):e58447.

https://www.jove.com/video/58447/exploring-effects-spaceflight-on-mouse-physiology-using-open-access

Note: ISS results. From the Introduction: "The overall goal of this manuscript is to provide a clear methodology of how to use NASA's GeneLab platform and how rodent experiments

done in space are translated to omics data for analysis." GeneLab is available at: https://genelab.nasa.gov/. This article may be obtained online without charge.

Journal Impact Factor: 0.971

Funding: "Research funding was provided by the GeneLab Project at NASA Ames Research Center, through NASA's Space Biology Program in the Division of Space Life and Physical Sciences Research and Applications (SLPSRA)."

 

2

Blaustein RA, McFarland AG, Ben Maamar S, Lopez A, Castro-Wallace S, Hartmann EM.

Pangenomic approach to understanding microbial adaptations within a model built environment, the International Space Station, relative to human hosts and soil.

mSystems. 2019 Jan 8;4(1):e00241-18.

https://www.ncbi.nlm.nih.gov/pubmed/30637341 

Note: ISS results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported in part by the Searle Leadership Fund and through the computational resources and staff contributions provided by the Genomics Compute Cluster, which is jointly supported by the Feinberg School of Medicine, the Center for Genetic Medicine, and Feinberg’s Department of Biochemistry and Molecular Genetics, the Office of the Provost, the Office for Research, and Northwestern Information Technology. The Genomics Compute Cluster is part of Quest, Northwestern University’s high-performance computing facility, with the purpose to advance research in genomics. R.A.B. is supported by a TL1 award (number TL1R001423) from the National Institutes of Health, National Center for Advancing Translational Science." S. Castro-Wallace is affiliated with NASA Johnson Space Center.

 

3

Burkhart K, Allaire B, Bouxsein M.

Negative effects of long-duration spaceflight on paraspinal muscle morphology.

Spine (Phila Pa 1976). 2018 Dec 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30624302

PI: M.L. Bouxsein

Note: ISS results.

Journal Impact Factor: 2.792

Funding: "National Aeronautics and Space Administration (NASA) grant NNX16AC15G and by the National Space Biomedical Research Institute through NASA NCC 9-58 funds were received in support of this work."

 

4

Lee TV, Lee CW, Chen VCW, Bui S, Fluckey JD, Riechman SE.

The effects of hindlimb unloading versus dietary cholesterol and resistance training on rat skeletal muscle responses.

Lipids Health Dis. 2019 Jan 5;18(1):3.

https://www.ncbi.nlm.nih.gov/pubmed/30611265

PI: S.A. Bloomfield

Note: Hindlimb unloading study. This article may be obtained online without charge.

Journal Impact Factor: 2.663

Funding: "This study was supported by the Sydney and J.L. Huffines Institute for Sports Medicine and Human Performance, and Texas A&M University Department of Health and Kinesiology. This work was also supported by the National Space Biomedical Research Institute through NCC 9–58."

 

5

Chatterjee S, Pietrofesa RA, Park K, Tao JQ, Carabe-Fernandez A, Berman AT, Koumenis C, Sielecki T, Christofidou-Solomidou M.

LGM2605 reduces space radiation-induced NLRP3 inflammasome activation and damage in in vitro lung vascular networks.

Int J Mol Sci. 2019 Jan 5;20(1):E176.

https://www.ncbi.nlm.nih.gov/pubmed/30621290

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: "This work was mainly funded by LignaMed, LLC via subaward to M.C.-S. (NASA-Phase I NNX17CL73P and NASA-Phase II 80NSSC18C0089). The work was also supported in part by 1P42ES023720-01 (M.C.-S.) and by pilot project support from 1P30 ES013508-02 awarded to M.C.-S. (its contents are solely the responsibility of the authors and do not necessarily represent the official views of the NIEHS, NIH)."

 

6

Howe A, Kiffer F, Alexander TC, Sridharan V, Wang J, Ntagwabira F, Rodriguez A, Boerma M, Allen AR.

Long-term changes in cognition and physiology after low-dose 16O irradiation.

Int J Mol Sci. 2019 Jan 7;20(1):E188.

https://www.ncbi.nlm.nih.gov/pubmed/30621014

PI: M. Boerma; M. Boerma/NSBRI Center for Research on Cardiac, Vascular, and Acute Effects of Space Radiation

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.687

Funding: "This work supported by the National Space Biomedical Research Institute [RE03701] through NCC 9-58 to MB], the National Aeronautics and Space Administration [80NSSC17K0425 to MB], and the National Institutes of General Medical Sciences [P20 GM109005 to MHJ]."

 

7

Jangiam W, Udomtanakunchai C, Reungpatthanaphong P, Tungjai M, Honikel L, Gordon CR, Rithidech KN.

Late effects of low-dose radiation on the bone marrow, lung, and testis collected from the same exposed BALB/cJ mice.

Dose Response. 2018 Dec 18;16(4):1559325818815031.

https://www.ncbi.nlm.nih.gov/pubmed/30622448

PI: K.N. Rithidech

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.435

Funding: "This research was supported by the National Aeronautics and Space Administration (NASA) Grant # NNX11AK91G, the DOE Grant #DE-FG02-02ER6331, and Stony Brook University."

 

8

Seawright JW, Sridharan V, Landes RD, Cao M, Singh P, Koturbash I, Mao XW, Miousse IR, Singh SP, Nelson GA, Hauer-Jensen M, Boerma M.

Effects of low-dose oxygen ions and protons on cardiac function and structure in male C57BL/6J mice.

Life Sci Space Res. 2019 Feb;20:72-84. Epub 2019 Jan 15.

http://www.sciencedirect.com/science/article/pii/S2214552418300798

PIs: M. Boerma/I. Koturbash/X.W. Mao/G.A. Nelson/M. Hauer-Jensen/NSBRI Center for Research on Cardiac, Vascular, and Acute Effects of Space Radiation

Journal Impact Factor: 1.97

Funding: "This work supported by the National Space Biomedical Research Institute [RE03701] through NCC 9-58 to MB], the National Aeronautics and Space Administration [80NSSC17K0425 to MB], and the National Institutes of General Medical Sciences [P20 GM109005 to MHJ]."

______________________________________________________

 

 

Other papers of interest:

 

1

Capri M, Morsiani C, Santoro A, Moriggi M, Conte M, Martucci M, Bellavista E, Fabbri C, Giampieri E, Albracht K, Flück M, Ruoss S, Brocca L, Canepari M, Longa E, Di Giulio I, Bottinelli R, Cerretelli P, Salvioli S, Gelfi C, Franceschi C, Narici M, Rittweger J.

Recovery from 6-month spaceflight at the International Space Station: Muscle-related stress into a proinflammatory setting.

FASEB J. 2019 Jan 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30620616

Note: ISS results.

 

2

Yurkevich OY, Samatadze TE, Levinskikh MA, Zoshchuk SA, Signalova OB, Surzhikov SA, Sychev VN, Amosova AV, Muravenko OV.

Molecular cytogenetics of Pisum sativum L. grown under spaceflight-related stress.

Biomed Res Int. 2018 Dec 6;2018:4549294.

https://www.ncbi.nlm.nih.gov/pubmed/30627557

Note: ISS results. This article may be obtained online without charge.

 

3

Sun X, Gao Y, Zhang J, Li C, Zhou H, Wang Y, Yang C.

[Development of a physical training system with lower body negative pressure].

Space Med Med Eng. 2018;31(5):567-70. Chinese.

http://caod.oriprobe.com/articles/54515961/Development_of_a_Physical_Training_System_with_Low.htm

 

4

Apostolopoulos A, Nakamura A, Yokoyama S, Aoshima M, Fujimoto R, Nakamura K, Ito R, Goto K.

Nuclear accumulation of HSP70 in mouse skeletal muscles in response to heat stress, aging, and unloading with or without reloading.

Front Genet. 2018 Dec 20;9:617.

https://www.ncbi.nlm.nih.gov/pubmed/30619453

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

5

Gliemann L, Rytter N, Piil P, Nilton J, Lind T, Nyberg M, Cocks M, Hellsten Y.

The endothelial mechanotransduction protein platelet endothelial cell adhesion molecule-1 is influenced by aging and exercise training in human skeletal muscle.

Front Physiol. 2018 Dec 18;9:1807.

https://www.ncbi.nlm.nih.gov/pubmed/30618819

Note: This article may be obtained online without charge.

 

6

McGlory C, Gorissen SHM, Kamal M, Bahniwal R, Hector AJ, Baker SK, Chabowski A, Phillips SM.

Omega-3 fatty acid supplementation attenuates skeletal muscle disuse atrophy during two weeks of unilateral leg immobilization in healthy young women.

FASEB J. 2019 Jan 10. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30629458

 

7

Olsen LA, Nicoll JX, Fry AC.

The skeletal muscle fiber: A mechanically sensitive cell.

Eur J Appl Physiol. 2019 Jan 5. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/30612167

 

8

Wang Z, Jiang SF, Cao J, Liu K, Xu SH, Arfat Y, Guo QL, Chang H, Goswami N, Hinghofer-Szalkay H, Gao YF.

Novel findings on ultrastructural protection of skeletal muscle fibers during hibernation of Daurian ground squirrels: Mitochondria, nuclei, cytoskeleton, glycogen.

J Cell Physiol. 2019 Jan 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30633347

 

9

Zheng H, She Q, Gao Y, Zhang Q, Luo Z.

[Intermuscular coupling analysis based on transfer entropy and generalized partial directed coherence].

Space Med Med Eng. 2018;31(5):538-44. Chinese.

http://caod.oriprobe.com/articles/54515953/Intermuscular_Coupling_Analysis_Based_on_Transfer_.htm

 

10

Cacao E, Kapukotuwa S, Cucinotta FA.

Modeling reveals the dependence of hippocampal neurogenesis radiosensitivity on age and strain of rats.

Front Neurosci. 2018 Dec 20;12:980.

https://www.ncbi.nlm.nih.gov/pubmed/30618596

Note: This article may be obtained online without charge.

 

11

Guerrero CC, Romero I, Arceo C, Gonzalez JE, Cortina-Ramirez GE, Garcia O.

Dose response of Prematurely Condensed Chromosome Rings after gamma irradiation.

Int J Radiat Biol. 2019 Jan 7. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30615557

 

12

Shibata A, Jeggo P.

A historical reflection on our understanding of radiation-induced DNA double strand break repair in somatic mammalian cells; interfacing the past with the present.

Int J Radiat Biol. 2019 Jan 4. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/30608893

 

13

Ma Q, Wu R, Du F, Xu Z, Tang Z, Xion J, Li Yi.

[Changes and influential factors of risk decision-making in isolated and confined environment].

Space Med Med Eng. 2018;31(5):507-12. Chinese.

http://caod.oriprobe.com/articles/54515950/Changes_and_Influential_Factors_of_Risk_Decision_m.htm

 

14

Geng H, Niu J, Pan D, Tian Z, Wang X, Zhang Y.

[Impact of task difficulty on workload in robotic arm teleoperation].

Space Med Med Eng. 2018;31(5):520-5. Chinese.

http://caod.oriprobe.com/articles/54515955/Impact_of_Task_Difficulty_on_Workload_in_Robotic_A.htm

 

15

Zhao G, Wang J, Gao J, Liu Y, Li Y.

[Research progress of effects of weightlessness/simulated weightlessness on fungi].

Space Med Med Eng. 2018;31(5):571-6. Chinese.

http://caod.oriprobe.com/articles/54515957/Research_Progress_of_Effects_of_Wightlessness_Simu.htm

Note: The method of microgravity simulation is not provided in the abstract.

 

16

Zabel P, Bornemann G, Tajmar M, Schubert D.

Yield of dwarf tomatoes grown with a nutrient solution based on recycled synthetic urine.

Life Sci Space Res. 2019 Feb;20:62-71. Epub 2019 Jan 15. http://www.sciencedirect.com/science/article/pii/S2214552418300749

 

17

Zhang N, Tang Y, Li J, Yang G.

[Dynamics of wheat growth development and biological characteristics in CELSS].

Space Med Med Eng. 2018;31(5):532-7. Chinese.

http://caod.oriprobe.com/articles/54515958/Dynamics_of_Wheat_Growth_Development_and_Biologica.htm

 

18

Gao J, Liu S, Feng Q, Zhang X, Zhang J, Jiang M, Wang L, Zhang Q.

Quantitative evaluations of the effects of noise on mental workloads based on pupil dilation during laparoscopic surgery.

Am Surg. 2018 Dec 1;84(12):1951-6.

https://www.ncbi.nlm.nih.gov/pubmed/30606354

Note: The NASA Task Load Index was used.

 

19

Law KE, Lowndes BR, Kelley SR, Blocker RC, Larson DW, Hallbeck MS, Nelson H.

NASA-Task Load Index differentiates surgical approach: Opportunities for improvement in colon and rectal surgery.

Ann Surg. 2018 Dec 29. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30614878

Note: The NASA Task Load Index was used.

 

20

Mohamadi M, Namnabati M, Aarabi A.

Reduced mental workload of neonatal intensive care unit nurses through a self-designed education class: A randomized controlled trial.

Iran J Nurs Midwifery Res. 2019 Jan-Feb;24(1):50-5.

https://www.ncbi.nlm.nih.gov/pubmed/30622578

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

...

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