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NASA Spaceline Current Awareness List #838 1 March 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, March 1, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

Papers deriving from NASA support:

1

Riascos RF, Kamali A, Hakimelahi R, Mwangi B, Rabiei P, Seidler RD, Behzad BB, Keser Z, Kramer LA, Hasan KM.

Longitudinal analysis of quantitative brain MRI in astronauts following microgravity exposure.

J Neuroimaging. 2019 Feb 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30784130

PI: R. Riascos

Note: Space Shuttle and ISS results.

Journal Impact Factor: 1.953

Funding: "This investigation was supported by a grant (NNX15AE25G) from the National Aeronautics and Space Administration (NASA), and the DUNN Research Fund for support to K.M.H."

 

2

Mujat M, Lu Y, Maguluri G, Zhao Y, Iftimia N, Ferguson RD.

Visualizing the vasculature of the entire human eye posterior hemisphere without a contrast agent.

Biomed Opt Express. 2019 Jan 1;10(1):167-80.

https://www.ncbi.nlm.nih.gov/pubmed/30775091

PI: M. Mujat

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.482

Funding: "National Aeronautics and Space Administration (NASA) (NNX16CC20C)."

 

3

Harding CP, Vargis E.

Muscle atrophy marker expression differs between rotary cell culture system and animal studies.

Biomed Res Int. 2019 Feb 17;2019:2042808.

https://www.hindawi.com/journals/bmri/2019/2042808/cta/

Note: A rotary cell culture system was used. This article may be obtained online without charge.

Journal Impact Factor:  2.583

Funding: "This work was supported by the Utah NASA Space Grant Consortium (UNSGC) Graduate Fellowship (C. Harding) and by the US Nuclear Regulatory Commission (NRC-HQ-84-15-G-0033)."

 

4

Rivera PD, Simmons SJ, Reynolds RP, Just AL, Birnbaum SG, Eisch AJ.

Image-guided cranial irradiation-induced ablation of dentate gyrus neurogenesis impairs extinction of recent morphine reward memories.

Hippocampus. 2019 Feb 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30779299

PI: A.J. Eisch

Journal Impact Factor: 3.966

Funding: "Foundation for the National Institutes of Health, Grant/Award Numbers: DA007290, DA016765, DA023555, MH107945; National Aeronautics and Space Administration, Grant/Award Numbers: NNX12AB55G, NNX15AE09G, 80NSSC17K0060; National Institute of Neurological Disorders and Stroke, Grant/Award Number: T32-NS007413; National Institute on Drug Abuse, Grant/Award Number: T32-DA07290."

 

5

Scott Carnell LA, Sidehamer TD, Hunter WA, Yagle JJ.

IBM Watson supporting space radiation.

Hampton, VA: NASA Langley Research Center, 2018 Jul. 12 p. NASA/TM–2018-220078.

https://ntrs.nasa.gov/search.jsp?R=20180006314 

Note: From the abstract: "The NASA Human Research Program (HRP) Space Radiation (SR) Program Element has been working with IBM Watson Explorer (WEX) to create a tool that allows researchers to search the NASA SR-funded research corpus to help streamline research and maximize efficiency." This report may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: No funding cited. L.A. Scott Carnell, W.A. Hunter, and J.J. Yagle are affiliated with NASA Langley Research Center.

 

6

McKenna MJ, Robinson E, Taylor L, Tompkins C, Cornforth MN, Simon SL, Bailey SM.

Chromosome translocations, inversions and telomere length for retrospective biodosimetry on exposed U.S. atomic veterans.

Radiat Res. 2019 Feb 4. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30714852

PI: M.N. Cornforth

Journal Impact Factor: 2.53

Funding: "This research was supported by the Intramural Research Program of the National Cancer Institute (NCI) with Colorado State University and KromaTiD, Inc. (PHR-SSS-S-15-004565; PHR-SSS-S-15-004209). Support at the NCI was derived from the Intra-Agency agreement between the Radiation Nuclear Countermeasures Program of the National Institute of Allergy and Infectious Diseases with the National Cancer Institute, NIAID agreement no. Y2-Al-5077 and NCI agreement no. Y3-CO-511."  PI reports funding under NASA grant NNX15AG74G.

 

7

Simon SL, Bailey SM, Beck HL, Boice JD, Bouville A, Brill AB, Cornforth MN, Inskip PD, McKenna MJ, Mumma MT, Salazar SI, Ukwuani A.

Estimation of radiation doses to U.S. military test participants from nuclear testing: A comparison of historical film-badge measurements, dose reconstruction and retrospective biodosimetry.

Radiat Res. 2019 Feb 21. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30789797

PI: M.N. Cornforth

Journal Impact Factor: 2.53

Funding: "This research was supported in part by the Intramural Research Program of the National Cancer Institute (NCI) and the Intra-Agency agreement between the Radiation Nuclear Countermeasures Program of the National Institute of Allergy and Infectious Diseases with the NCI, NIAID agreement no. Y2-Al-5077 and NCI agreement no. Y3-CO-511, and by contracts and grants from the NCI (grant no. U01 CA137026), the U.S. Department of Energy (grant no. DE-SC0008944) awarded to the National Council on Radiation Protection and Measurements and a discovery grant from the Vanderbilt-Ingram Cancer Center (Center no. 404-357-9682)." PI reports funding under NASA grant NNX15AG74G.

 

8

Dorais GA.

An evolutionary computation system design concept for developing controlled closed ecosystems: An intelligent systems approach to foster gravitational ecosystem research for developing sustainable communities in space and on Earth.

Moffett Field, CA: NASA Ames Research Center, 2018 Nov. 37 p. NASA/TM-2018–56787.

https://ntrs.nasa.gov/search.jsp?R=20190000114 

Note: This report may be obtained online without charge.

Journal Impact Factor: Not applicable to this publication

Funding: No funding cited. G.A. Dorais is affiliated with NASA Ames Research Center.

______________________________________________________

 

 

Other papers of interest:

 

1

Winter J, Laing C, Johannes B, Mulder E, Brix B, Roessler A, Reichmuth J, Rittweger J, Goswami N.

Galanin and adrenomedullin plasma responses during artificial gravity on a human short-arm centrifuge.

Front Physiol. 2018 Feb 1;9:1956.

https://www.ncbi.nlm.nih.gov/pubmed/30774604

Note: A short-arm centrifuge was used. This article may be obtained online without charge.

 

2

Mo L, Wang H, He B, Jin Z, Geng X, Zhang L, Wei X, Wang Q, Xu Y, Wu S, H. W, Li B.

[Design and verification of ear pulse collection device in human centrifuge].

Space Med Med Eng. 2018;2018(6):618-22. Chinese.

http://caod.oriprobe.com/articles/55275544/Design_and_Verification_of_Ear_Pulse_Collection_De.htm

Note: Centrifugation was used.

 

3

Watts AJ, Storey KB.

Hibernation impacts lysine methylation dynamics in the 13-lined ground squirrel, Ictidomys tridecemlineatus.

J Exp Zool A Ecol Integr Physiol. 2019 Feb 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30767414

 

4

Liu J, Yuan M, Jia M, Zhengm H, Yao J, Yuan M, Wang J, Hu T.

[Transcriptomics study on effects of oxidative stress on EA.hy926 cells under simulated microgravity].

Space Med Med Eng. 2018;2018(6):583-9. Chinese.

http://caod.oriprobe.com/articles/55275545/Transcriptomics_Study_on_Effects_of_Oxidative_Stre.htm  

Note: A clinostat was used.

 

5

Elliott J, Adegbie D, Bhagwat R, Sule ES, Ahmad M.

Taking radiation exposure and cardiovascular health a step further... one small step for man, one giant leap for medical research.

J Radiol Prot. 2019 Feb 11. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30743249

Note: This article is a comment on Horita S, Kusama T, Ban N. Effect of age-related baseline risk on radiation dose response for coronary heart disease. J Radiol Prot. 2018 Dec;38(4):1469-1482. https://www.ncbi.nlm.nih.gov/pubmed/30398167. In the original article, the authors "estimate the mortality risk of radiation-associated coronary heart disease (CHD) by using a model in which radiation was assumed to participate in the atherosclerotic process jointly with ageing" (from the abstract). The Letter to the Editor discusses the possible effects of space radiation on development of CHD in astronauts on a mission to Mars.

 

6

Mitchell A, Pimenta D, Gill J, Ahmad H, Bogle R.

Cardiovascular effects of space radiation: Implications for future human deep space exploration.

Eur J Prev Cardiol. 2019 Feb 18. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30776915

 

7

Xiong K, Xu L, Cheng S, Ma J, Wang C, Hu W.

[Research on fatigue of lower back muscles caused by simulated sitting posture during flight based on surface electromyography].

Space Med Med Eng. 2018;2018(6):590-4. Chinese.

http://caod.oriprobe.com/articles/55275553/Research_on_Fatigue_of_Lower_Back_Muscles_Caused_b.htm  

 

8

Wang Z, Tang X, Liu W, Li R.

[Review of on-orbit sleep and its effects on cognition of astronauts].

Space Med Med Eng. 2018;2018(6):663-8. Chinese.

http://caod.oriprobe.com/articles/55275547/Review_of_On_orbit_Sleep_and_Its_Effects_on_Cognit.htm

 

9

Kong X, Liu Y, An M, Liu X, Hu F, Yang Y.

[Research on influence of interactive mode on astronaut virtual training efficiency and experience].

Space Med Med Eng. 2018;2018(6):595-600. Chinese.

http://caod.oriprobe.com/articles/55275551/Research_on_Influence_of_Interactive_Mode_on_Astro.htm  

 

10

Menger R, Kelly P, Fernando S, Wolf ME, Martino A.

Rear Admiral (Astronaut) Alan Shepard: Ménière's disease and the race to the moon.

J Neurosurg. 2019 Feb 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30771763

Note: The article provides details about the effects of Ménière's disease on Alan Shepard's career and the successful surgical treatment by Dr. William F. House. The article is accompanied by an editorial:  Rutka J. Editorial. Rear Admiral (Astronaut) Alan Shepard: De mortuis nil nisi bonum (say nothing bad of the departed). J Neurosurg. 2019 Feb 15. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/30771767.

 

11

Rutka J.

Editorial. Rear Admiral (Astronaut) Alan Shepard: De mortuis nil nisi bonum (say nothing bad of the departed).

J Neurosurg. 2019 Feb 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30771767

Note: This is a comment on the preceding article: Menger R, Kelly P, Fernando S, Wolf ME, Martino A. Rear Admiral (Astronaut) Alan Shepard: Ménière's disease and the race to the moon. J Neurosurg. 2019 Feb 15:1-7. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/30771763.

 

12

Antonova EV, Khlestkina EK.

Radiosensitivity and mutability of wheat seed progeny cultivated under adverse environments.

Plant Physiol Biochem. 2019 Feb 14;137:162-8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30784988

Note: From the abstract: "We used acute gamma irradiation (5-50 Gy) as a provocative factor to detect hidden differences in the adaptive potential of seeds cultivated under adverse conditions (wet and cold field season) in comparison to seeds obtained under controlled conditions (hydroponic greenhouse)."

 

13

Chapman JM, Muhlemann JK, Gayomba SR, Muday GK.

RBOH-dependent ROS synthesis and ROS scavenging by plant specialized metabolites to modulate plant development and stress responses.

Chem Res Toxicol. 2019 Feb 20. [Epub ahead of print] Review.

https://www.ncbi.nlm.nih.gov/pubmed/30781949

 

14

Mao R, Tang Y, Zhang C, Ji Y, Shuangsheng G.

[Effects of four-color LED light quality on growth and synthetic and oxygen-releasing efficiency of Arthrospira platensis]. 

Space Med Med Eng. 2018;2018(6):607-12. Chinese.

http://caod.oriprobe.com/articles/55275548/Effects_of_Four_color_LED_Light_Quality_on_Growth_.htm

 

15

Vazquez MM, Casalongue CA, Paris R.

Nitrate reductase mediates nitric oxide-dependent gravitropic response in Arabidopsis thaliana roots.

Plant Signal Behav. 2019 Feb 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30782074

 

16

Tang Y, Wu Z, Dong W.

[Review and analysis of Antarctic plant production facilities].

Space Med Med Eng. 2018;2018(6):669-75. Chinese.

http://caod.oriprobe.com/articles/55275546/Review_and_Analysis_of_Antarctic_Plant_Production_.htm 

 

17

Wu C, Ai W, Luo Y, Zhang L, Yang J, Li  P, Tian J.

[Study on pretreatment technology of inedible biomass in controlled ecological life support system integrated experiment].

Space Med Med Eng. 2018;2018(6):613-7. Chinese.

http://caod.oriprobe.com/articles/55275554/Study_on_Pretreatment_Technology_of_Inedible_Bioma.htm

 

18

Criss CN, Jarboe MD, Claflin J, Matusko N, Rooney DM.

Evaluating a solely mechanical articulating laparoscopic device: A prospective randomized crossover study.

J Laparoendosc Adv Surg Tech A. 2019 Feb 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30785844

Note: The NASA Task Load Index was used.

 

19

Hollands JG, Spivak T, Kramkowski EW.

Cognitive load and situation awareness for soldiers: Effects of message presentation rate and sensory modality.

Hum Factors. 2019 Feb 15. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30768371

Note: The NASA Task Load Index was used.

// end //

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