SpaceRef

SpaceRef


NASA Spaceline Current Awareness List #840 15 March 2019 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, March 15, 2019

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.


Papers deriving from NASA support:

 

1

Alexander AM, Didier KD, Hammer SM, Dzewaltowski AC, Kriss KN, Lovoy GM, Hammer JL, Smith JR, Ade CJ, Broxterman RM, Barstow TJ.

Exercise tolerance through severe and extreme intensity domains.

Physiol Rep. 2019 Mar;7(5):e14014.

https://www.ncbi.nlm.nih.gov/pubmed/30825269

PI: T.J. Barstow

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "A. M. Alexander, C. J. Ade, T. J. Barstow, and S. M. Hammer were supported by NASA grant NNX16AF66A."

 

2

Hughes AM, Hancock GM, Marlow SL, Stowers K, Salas E.

Cardiac measures of cognitive workload: A meta-analysis.

Hum Factors. 2019 Mar 1. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30822151

PI: E. Salas

Journal Impact Factor: 2.371

Funding: "...this project was partially funded by NASA Grant NNX15AR28G to Rice University."

 

3

Michalski AS, Amin S, Cheung AM, Cody DD, Keyak JH, Lang TF, Nicolella DP, Orwoll ES, Boyd SK, Sibonga JD.

Hip load capacity cut-points for Astronaut Skeletal Health NASA Finite Element Strength Task Group Recommendations.

npj Microgravity. 2019 Mar 14;5(1):6.

https://www.nature.com/articles/s41526-019-0066-3

PI: J.D. Sibonga

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.00

Funding: "This work was funded in part by the NASA Human Research Program. The Age, Gene/Environment Susceptibility Reykjavik Study is funded by NIH contract N01-AG-12100, the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament). The study was approved by the Icelandic National Bioethics Committee (VSN: 00-063) and the Data Protection Authority. This study was also made possible by the Rochester Epidemiology Project."

 

4

Cohen HS, Mulavara AP, Stitz J, Sangi-Haghpeykar H, Williams SP, Peters BT, Bloomberg JJ.

Screening for vestibular disorders using the modified clinical test of sensory interaction and balance and tandem walking with eyes closed.

Otol Neurotol. 2019 Feb 27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30829953

PIs: A.P. Mulavara, J.J. Bloomberg

Journal Impact Factor: 2.182

Funding: "Funding/Support: NIH grant 2R01DC009031 (HSC), National Space Biomedical Research Institute through NASA NCC 9-58 (A.P.M., J.J.B.), and a fellowship from the Austria Marshall Plan Foundation (J.S.)."

 

Note: Astrobiology has published a Special Collection on NASA’s BASALT (Biologic Analog Science Associated with Lava Terrains) Program. Since many of the articles discuss human research on Mars, the entire issue is listed here. The articles are available free of charge. The issue can be found at https://www.liebertpub.com/toc/ast/19/3.

 

5

Love SG.

BASALT: The future of Mars, on Earth today.

Astrobiology. 2019 Mar;19(3):243-4.

https://www.ncbi.nlm.nih.gov/pubmed/30199267

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: No funding cited. The author is affiliated with NASA Johnson Space Center.

 

6

Lim DSS, Abercromby AFJ, Kobs Nawotniak SE, Lees DS, Miller MJ, Brady AL, Miller MJ, Mirmalek Z, Sehlke A, Payler SJ, Stevens AH, Haberle CW, Beaton KH, Chappell SP, Hughes SS, Cockell CS, Elphic RC, Downs MT, Heldmann JL. 

The BASALT Research Program: Designing and developing mission elements in support of human scientific exploration of Mars.

Astrobiology. 2019 Mar;19(3):245-59.

https://www.ncbi.nlm.nih.gov/pubmed/30840510

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "The authors are grateful for the NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S.L., with additional support from NASA SSERVI FINESSE grant to J.L.H."

 

7

Hughes SS, Haberle CW, Kobs Nawotniak SE, Sehlke A, Garry WB, Elphic RC, Payler SJ, Stevens AH, Cockell CS, Brady AL, Heldmann JL, Lim DSS.

Basaltic terrains in Idaho and Hawai'i as planetary analogs for Mars geology and astrobiology.

Astrobiology. 2019 Mar;19(3):260-83.

https://www.ncbi.nlm.nih.gov/pubmed/30339033

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "Support for this program was provided by BASALT, D.S.S.L., Principal Investigator, funded by the NASA Planetary Science and Technology through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S.L.; and by FINESSE (Field Investigations to Enable Solar System Science and Exploration), J.L.H., Principal Investigator, funded by the NASA Solar System Exploration Research Virtual Institute (SSERVI)."

 

8

Cockell CS, Harrison JP, Stevens AH, Payler SJ, Hughes SS, Kobs Nawotniak SE, Brady AL, Elphic RC, Haberle CW, Sehlke A, Beaton KH, Abercromby AFJ, Schwendner P, Wadsworth J, Landenmark H, Cane R, Dickinson AW, Nicholson N, Perera L, Lim DSS. 

A low-diversity microbiota inhabits extreme terrestrial basaltic terrains and their fumaroles: Implications for the exploration of Mars.

Astrobiology. 2019 Mar;19(3):284-99.

https://www.ncbi.nlm.nih.gov/pubmed/30840501

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This work was supported by the NASA Planetary Science and Technology Through Analog Research (PSTAR) program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_20007) to D. Lim."

 

9

Beaton KH, Chappell SP, Abercromby AFJ, Miller MJ, Kobs Nawotniak SE, Brady AL, Stevens AH, Payler SJ, Hughes SS, Lim DSS.

Using science-driven analog research to investigate extravehicular activity science operations concepts and capabilities for human planetary exploration.

Astrobiology. 2019 Mar;19(3):300-20.

https://www.ncbi.nlm.nih.gov/pubmed/30840499

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This work is supported by the NASA Planetary Science and Technology through Analog Research program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D. Lim. The Science Operations research was approved through the NASA Johnson Space Center Institutional Review Board (Protocol ID 2202)."

 

10

Beaton KH, Chappell SP, Abercromby AFJ, Miller MJ, Kobs Nawotniak SE, Brady AL, Stevens AH, Payler SJ, Hughes SS, Lim DSS.

Assessing the acceptability of science operations concepts and the level of mission enhancement of capabilities for human Mars exploration extravehicular activity.

Astrobiology. 2019 Mar;19(3):321-46.

https://www.ncbi.nlm.nih.gov/pubmed/30840507

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This work is supported by the NASA Planetary Science and Technology through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D. Lim. The Science Operations research conducted during BASALT field tests was approved through the NASA JSC Institutional Review Board (Protocol ID 2202)."

 

11

Brady AL, Kobs Nawotniak SE, Hughes SS, Payler SJ, Stevens AH, Cockell CS, Elphic RC, Sehlke A, Haberle CW, Slater GF, Lim DSS.

Strategic planning insights for future science-driven extravehicular activity on Mars.

Astrobiology. 2019 Mar;19(3):347-68.

https://www.ncbi.nlm.nih.gov/pubmed/30840500

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "Funding support was provided by a Canadian Space Agency Flights and Fieldwork for the Advancement of Science and Technology (FAST) grant to G.S. as well as the NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S.L."

 

12

Stevens AH, Kobs Nawotniak SE, Garry WB, Payler SJ, Brady AL, Miller MJ, Beaton KH, Cockell CS, Lim DSS.

Tactical scientific decision-making during crewed astrobiology Mars missions.

Astrobiology. 2019 Mar;19(3):369-86.

https://www.ncbi.nlm.nih.gov/pubmed/30840503

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "The BASALT research program is supported by NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D. Lim."

 

13

Payler SJ, Mirmalek Z, Hughes SS, Kobs Nawotniak SE, Brady AL, Stevens AH, Cockell CS, Lim DSS.

Developing intra-EVA science support team practices for a human mission to Mars.

Astrobiology. 2019 Mar;19(3):387-400.

https://www.ncbi.nlm.nih.gov/pubmed/30840508

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This work was supported by the NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N–PSTAR) grant (14–PSTAR14_2–0007) to D. Lim."

 

14

Sehlke A, Mirmalek Z, Burtt D, Haberle CW, Santiago-Materese D, Kobs Nawotniak SE, Hughes SS, Garry WB, Bramall N, Brown AJ, Heldmann JL, Lim DSS.

Requirements for portable instrument suites during human scientific exploration of Mars.

Astrobiology. 2019 Mar;19(3):401-25.

https://www.ncbi.nlm.nih.gov/pubmed/30840506

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This research is supported by the NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2–0007) to D. Lim with additional support from NASA SSERVI FINESSE grant to J. Heldmann at the NASA Ames Research Center."

 

15

Kobs Nawotniak SE, Miller MJ, Stevens AH, Marquez JJ, Payler SJ, Brady AL, Hughes SS, Haberle CW, Sehlke A, Beaton KH, Chappell SP, Elphic RC, Lim DSS.

Opportunities and challenges of promoting scientific dialog throughout execution of future science-driven extravehicular activity.

Astrobiology. 2019 Mar;19(3):426-39.

https://www.ncbi.nlm.nih.gov/pubmed/30840509

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "The BASALT project is supported by NASA Planetary Science and Technology Through Analog Research (PSTAR) program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S."

 

16

Marquez JJ, Miller MJ, Cohen T, Deliz I, Lees DS, Zheng J, Lee YJ, Kanefsky B, Norheim J, Deans M, Hillenius S.

Future needs for science-driven geospatial and temporal extravehicular activity planning and execution.

Astrobiology. 2019 Mar;19(3):440-61.

https://www.ncbi.nlm.nih.gov/pubmed/30840505

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "This work was funded by NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D. Lim."

 

17

Seibert MA, Lim DSS, Miller MJ, Santiago-Materese D, Downs MT.

Developing future deep-space telecommunication architectures: A historical look at the benefits of analog research on the development of solar system internetworking for future human spaceflight.

Astrobiology. 2019 Mar;19(3):462-77.

https://www.ncbi.nlm.nih.gov/pubmed/30840504

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "...NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S.L."

 

18

Miller MJ, Miller MJ, Santiago-Materese D, Seibert MA, Lim DSS.

A flexible telecommunication architecture for human planetary exploration based on the BASALT science-driven Mars analog.

Astrobiology. 2019 Mar;19(3):478-96.

https://www.ncbi.nlm.nih.gov/pubmed/30840502

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.610

Funding: "The authors would like to thank the NASA Planetary Science and Technology Through Analog Research (PSTAR) Program (NNH14ZDA001N-PSTAR) grant (14-PSTAR14_2-0007) to D.S.S. Lim, with additional support from NASA SSERVI FINESSE grant to J. Heldmann."

______________________________________________________

 

Other papers of interest:

 

1

Pastushkova LH, Rusanov VB, Goncharova AG, Brzhozovskiy AG, Kononikhin AS, Chernikova AG, Kashirina DN, Nosovsky AM, Baevsky RM, Nikolaev EN, Larina IM.

Urine proteome changes associated with autonomic regulation of heart rate in cosmonauts.

BMC Syst Biol. 2019 Mar 5;13(Suppl 1):17.

https://www.ncbi.nlm.nih.gov/pubmed/30836973

Note: ISS results. This article may be obtained online without charge.

 

2

Ganapathy K, da Rosa M, Russomano T.

Neurological changes in outer space.

Neurol India. 2019 Jan 1;67(1):37-43.

http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2019;volume=67;issue=1;spage=37;epage=43;aulast=Ganapathy

Note: ISS results are discussed. This article may be obtained online without charge.

 

3

Deng B, Liu R, Tian X, Han Z, Chen J.

Simulated microgravity inhibits the viability and migration of glioma via FAK/RhoA/Rock and FAK/Nek2 signaling.

In Vitro Cell Dev Biol Anim. 2019 Feb 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30820814

Note: A clinostat was used.

 

4

Li WY, Tian YH, Gao YH, Zhu BY, Xi HR, Chen KM.

[Different types of low-frequency electromagnetic fields resist bone loss caused by weightlessness].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Feb 28;41(1):11-20. Chinese.

https://www.ncbi.nlm.nih.gov/pubmed/30837037

Note: Hindlimb unloading study.

 

5

Wang S, Yang X, Wang M, Huang Y, Blottner D, Sun LW, Fan YB.

The role of body fluid shifts on hindlimb bone loss in tail suspended rats using a novel body fluid alteration device.

Acta Astronaut. 2019 Mar 6. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576518311354

Note: Hindlimb unloading study.

 

6

Boice JD Jr, Cohen SS, Mumma MT, Ellis ED.

The Million Person Study, whence it came and why.

Int J Radiat Biol. 2019 Mar 4. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30831042

Note: From the abstract: "The Million Person Study of Low-Dose Health Effects (MPS) was designed to evaluate radiation risks among healthy American workers and veterans who are more representative of today’s populations than are the Japanese atomic bomb survivors exposed briefly to high-dose radiation in 1945." This is a companion article to Boice JD Jr., The Million Person Study relevance to space exploration and Mars, listed below.

 

7

Boice JD Jr.

The Million Person Study relevance to space exploration and Mars.

Int J Radiat Biol. 2019 Mar 4. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30831048

Note: From the Conclusion: "The MPS provides a more representative group (healthy men and women) for risk estimates than the 1945 Japanese population exposed briefly to the atomic bombs."

 

8

Minkoff BB, Bruckbauer ST, Sabat G, Cox MM, Sussman MR.

Covalent modification of amino acids and peptides induced by ionizing radiation from an electron beam linear accelerator used in radiotherapy.

Radiat Res. 2019 Mar 8. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30849023

 

9

Nguyen P, Shukla S, Liu R, Abbineni G, Smart DK.

SIRT2 regulates radiation-induced injury.

Radiat Res. 2019 Mar 5. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30835165

 

10

Park BK, Lee JH, Seo HW, Oh KS, Lee JH, Lee BH.

Icariin protects against radiation-induced mortality and damage in vitro and in vivo.

Int J Radiat Biol. 2019 Mar 4:1-27. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30831047

 

11

Rakusová H, Han H, Valošek P, Friml J.

Genetic screen for factors mediating PIN polarization in gravistimulated Arabidopsis thaliana hypocotyls.

Plant J. 2019 Feb 28. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30821050

Note: Plants were turned 90º for gravity stimulation.

 

12

Yu L, Liu Y, Xu F.

Comparative transcriptome analysis reveals significant differences in the regulation of gene expression between hydrogen cyanide- and ethylene-treated Arabidopsis thaliana.

BMC Plant Biol. 2019 Mar 4;19(1):92.

https://www.ncbi.nlm.nih.gov/pubmed/30832566

Note: This article may be obtained online without charge.

 

13

Maciolek KA, Best SL.

How do astronauts urinate? The history of innovations enabling voiding in the void.

Urology. 2019 Feb 26. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/30822481

 

14

Cockell CS, McLaughlin S.

Effects of rapid depressurisation on the structural integrity of common foodstuffs.

Acta Astronaut. 2019 Mar 6. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576518303291

Note: The authors exposed foodstuffs to a simulated rapid depressurization from atmospheric pressure to average Martian surface pressure (6 mb) to study the effects on structural integrity of foodstuffs and draw conclusions about appropriate approaches to the storage of food in extraterrestrial settlements.

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.