SpaceRef

SpaceRef


NASA Spaceline Current Awareness List #892 27 March 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, March 27, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Cepeda C, Vergnes L, Carpo N, Schibler MJ, Bentolila A, Karouia F, Espinosa-Jeffrey A.

Human neural stem cells flown into space proliferate and generate young neurons.

Appl Sci. 2019 Sep 29;9(19):4042.

https://www.mdpi.com/2076-3417/9/19/4042

PI: A. Espinosa-Jeffrey

Note: ISS results. This article belongs to the Special Issue Advances in Space Biology: Cell Behavior in Microgravity available at https://www.mdpi.com/journal/applsci/special_issues/Space_Biology. This article may be obtained online without charge.

Journal Impact Factor: 2.217

Funding: "NASA Space Biology Grant: NNX15AB43G; the Cell, Circuits and Systems Analysis Core is supported by the NIH (Grant U54HD087101). Time-lapse microscopy was performed at the Advanced Light Microscopy/Spectroscopy Laboratory and the Leica Microsystems Center of Excellence at the California NanoSystems Institute at UCLA with funding support from NIH Shared Instrumentation Grant S10OD025017 and NSF Major Research Instrumentation grant CHE-0722519."

 

2

Stamps BW, Bojanowski CL, Drake CA, Nunn HS, Lloyd PF, Floyd JG, Emmerich KA, Neal AR, Crookes-Goodson WJ, Stevenson BS.

In situ linkage of fungal and bacterial proliferation to microbiologically influenced corrosion in B20 biodiesel storage tanks.

Front Microbiol. 2020 Feb 25;11:167.

https://www.ncbi.nlm.nih.gov/pubmed/32174893

PI: B.W. Stamps, Sloan ISS MoBE Postdoctoral Fellowship

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.259

Funding: "The work presented was supported by the United States Air Force, AFRL Biological Materials and Processing Research Team, Materials and Manufacturing Directorate as a subcontract to BSS (S-111-016-001) through UES's prime contract FA8650-15-D-5405, task order 001; and partly through a grant awarded to BSS from the United States Air Force Academy through the Secretary of Defense's Corrosion Protection Office Technical Corrosion Collaboration Program (TCC; FA7000-15-2-0001). BWS was supported during the writing of the manuscript by the Sloan Foundation Fellowship G-2017-9853."

 

3

Laurie SS, Christian K, Kysar J, Lee SMC, Lovering AT, Macias BR, Moestl S, Sies W, Mulder E, Young M, Stenger MB.

Unchanged cerebrovascular CO2 reactivity and hypercapnic ventilatory response during strict head-down tilt bed rest in a mild hypercapnic environment.

J Physiol. 2020 Mar 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32196672

PI: S.S. Laurie

Note: Head-down tilt bed rest study.

Journal Impact Factor: 4.950

Funding: "Funding was obtained from NASA in response to NASA Research Announcement NNJ14ZSA001N-MIXEDTOPICS."

 

4

Keyak JH, Kaneko TS, Khosla S, Amin S, Atkinson EJ, Lang TF, Sibonga JD.

Hip load capacity and yield load in men and women of all ages.

Bone. 2020 Mar 14. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32184195

PIs: J.D. Sibonga, T.F. Lang

Journal Impact Factor: 4.360

Funding: "This work was supported by NIH/NIA R01AG028832, NIH/NIAMS R01AR46197, NIH/NIAMS R01AR060700, NIH/NIAMS R01AR064140, by NIH/NIAMS grants AR-27065 and M01 RR00585 and by NASA grants NNJ04HC7SA, NNJ04HF78G, NNJ12HC91P. This study was made possible by the Rochester Epidemiology Project. We thank Dr. Vilmundur Gudnason (Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland) for the opportunity to include data from the AGES cohort. The Age, Gene/Environment Susceptibility Reykjavik Study was funded by NIH contract N01-AG-12100, the NIA Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (the Icelandic Parliament) and was approved by the Icelandic National Bioethics Committee (VSN: 00-063) and the Data Protection Authority."

 

5

Nia AM, Chen T, Barnette BL, Khanipov K, Ullrich RL, Bhavnani SK, Emmett MR.

Efficient identification of multiple pathways: RNA-Seq analysis of livers from 56Fe ion irradiated mice.

BMC Bioinformatics. 2020 Mar 20;21(1):118.

https://www.ncbi.nlm.nih.gov/pubmed/32192433

PI: M.R. Emmett

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.511

Funding: "This work was supported by the Ground-Based Studies in Space Radiobiology through the National Aeronautics and Space Administration NASA (NNX15AD65G)."

 

6

Butler MP, Thosar SS, Smales C, DeYoung PN, Wu H, Hussain MV, Morimoto M, Hu K, Scheer F, Shea SA.

Effects of obstructive sleep apnea on endogenous circadian rhythms assessed during relaxed wakefulness: An exploratory analysis.

Chronobiol Int. 2020 Mar 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32192382

PI: S.S. Thosar, NSBRI First Award Fellowship

Journal Impact Factor: 2.562

Funding: "This work was funded by an American Sleep Medicine Foundation Focused Project Award, T32-HL007901, and R21-HL140377 (MPB); R21-HL092407 and R01-HL125893 (SAS); F32-HL131308, KL2TR002370, and National Space Biomedical Research Institute through NCC 9-58 (SST); 1UL1-RR025758 and 8UL1-TR000170 to the Harvard Catalyst Clinical and Translational Science Center; and by the Oregon Institute of Occupational Health Sciences at Oregon Health & Science University via funds from the Division of Consumer and Business Services of the State of Oregon (ORS 656.630)."

 

7

Walton ME, Kerstman EL.

Quantification of medical risk on the International Space Station using the integrated medical model.

Aerosp Med Hum Perform. 2020 Apr;91(4):332-42.

https://www.ingentaconnect.com/content/asma/amhp/2020/00000091/00000004/art00006

Journal Impact Factor: 0.889

Funding: No funding cited. The authors are affiliated with NASA Johnson Space Center.

 

8

Vu LQ, Kim KH, Schulze LJH, Rajulu SL.

Lumbar posture assessment with fabric strain sensors.

Comput Biol Med. 2020 Mar;118:103624.

https://www.ncbi.nlm.nih.gov/pubmed/32174329

Journal Impact Factor: 2.286

Funding: "This study was partially funded by NASA HHPC NNJ15HK11B, USA."

 

9

Tucker R, Callaham JA, Zeidler C, Paul A-L, Ferl RJ.

NDVI Imaging within space exploration plant growth modules – A case study from EDEN ISS Antarctica.

Life Sci Space Res. 2020 Mar 24. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552420300183

PIs: R.J. Ferl, A-L. Paul

Journal Impact Factor: 2.066

Funding: "This work was supported by NASA SLPSRA grant 80NSSC17K0199 and the Florida Space Grant Consortium grant FSGC NNX15_016 FSGC08 170829 to RJF and A-LP. The EDEN ISS project received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 636501." 

 

Other papers of interest:

 

1

Klein T, Sanders M, Wollseiffen P, Carnahan H, Abeln V, Askew CD, Claassen J, Schneider S.

Transient cerebral blood flow responses during microgravity.

Life Sci Space Res. 2020 Mar 19. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S221455242030016X

Note: Parabolic flight results.

 

2

Simka M, Latacz P, Redelbach W.

Blood flow in the internal jugular veins during the spaceflight – Is it actually bidirectional?

Life Sci Space Res. 2020 Mar 19. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552420300171

Note: ISS results.

 

3

Wu Y, Xie J, Wang L, Zheng H.

Circumnutation and growth of inflorescence stems of Arabidopsis thaliana in response to microgravity under different photoperiod conditions.

Life (Basel). 2020 Mar 18;10(3):E26.

https://www.ncbi.nlm.nih.gov/pubmed/32197304

Note: Chinese spacelab TG-2 and recoverable satellite SJ-10 results. This article may be obtained online without charge.

 

4

Aventaggiato M, Barreca F, Vernucci E, Bizzarri M, Ferretti E, Russo MA, Tafani M.

Putative receptors for gravity sensing in mammalian cells: The effects of microgravity.

Appl Sci. 2020 Mar 17;10(6):2028. Review.

https://www.mdpi.com/2076-3417/10/6/2028

Note: Studies reviewed used ISS results, random positioning machines, and the Rotary Cell Culture System. This article belongs to the Special Issue Advances in Space Biology: Cell Behavior in Microgravity available at https://www.mdpi.com/journal/applsci/special_issues/Space_Biology. This article may be obtained online without charge.

 

5

Li BB, Chen ZY, Jiang N, Guo S, Yang JQ, Chai SB, Yan HF, Sun PM, Hu G, Zhang T, Xu BX, Sun HW, Zhou JL, Yang HM, Cui Y.

Simulated microgravity significantly altered metabolism in epidermal stem cells.

In Vitro Cell Dev Biol Anim. 2020 Mar 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32198676

Note: A Rotary Cell Culture System was used. This article may be obtained online without charge.

 

6

Mol A, Maier AB, van Wezel RJA, Meskers CGM.

Multimodal monitoring of cardiovascular responses to postural changes.

Front Physiol. 2020 Mar 3;11:168.

https://www.ncbi.nlm.nih.gov/pubmed/32194438

Note: This article may be obtained online without charge.

 

7

Arentson-Lantz EJ, Fiebig KN, Anderson-Catania KJ, Deer RR, Wacher A, Fry CS, Lamon S, Paddon-Jones D.

Countering disuse atrophy in older adults with low volume leucine supplementation.

J Appl Physiol (1985). 2020 Mar 19. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32191600

 

8

Ascolani G, Skerry TM, Lacroix D, Dall'Ara E, Shuaib A.

Revealing hidden information in osteoblast's mechanotransduction through analysis of time patterns of critical events.

BMC Bioinformatics. 2020 Mar 18;21(1):114.

https://www.ncbi.nlm.nih.gov/pubmed/32183690

Note: This article may be obtained online without charge.

 

9

Doron O, Samuel O, Karfunkel-Doron D, Tal D.

Scopolamine treatment and adaptation to airsickness.

Aerosp Med Hum Perform. 2020 Apr;91(4):313-7.

https://www.ingentaconnect.com/content/asma/amhp/2020/00000091/00000004/art00003

 

10

Kuiper OX, Bos JE, Diels C, Schmidt EA.

Knowing what's coming: Anticipatory audio cues can mitigate motion sickness.

Appl Ergon. 2020 May;85:103068. Epub 2020 Feb 6.

https://www.ncbi.nlm.nih.gov/pubmed/32174356

 

11

Kuldavletova O, Tanguy S, Denise P, Quarck G.

Vestibulo-ocular responses, visual field dependence, and motion sickness in aerobatic pilots.

Aerosp Med Hum Perform. 2020 Apr;91(4):326-31.

https://www.ingentaconnect.com/content/asma/amhp/2020/00000091/00000004/art00005

 

12

Morris MB, Howland JP, Amaddio KM, Gunzelmann G.

Aircrew fatigue perceptions, fatigue mitigation strategies, and circadian typology.

Aerosp Med Hum Perform. 2020 Apr;91(4):363-8.

https://www.ingentaconnect.com/content/asma/amhp/2020/00000091/00000004/art00011

 

13

Rahman SA, Rood D, Trent N, Solet J, Langer EJ, Lockley SW.

Manipulating sleep duration perception changes cognitive performance – An exploratory analysis.

J Psychosom Res. 2020 May;132:109992. Epub 2020 Mar 4.

https://www.ncbi.nlm.nih.gov/pubmed/32172039

 

14

MacDonald JG, Rodriguez K, Quirk S.

An oxygen delivery polymer enhances seed germination in a Mars-like environment.

Astrobiology. 2020 Mar 20. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32196355

Note: This article may be obtained online without charge.

 

15

McWhite CD, Papoulas O, Drew K, Cox RM, June V, Dong OX, Kwon T, Wan C, Salmi ML, Roux SJ, Browning KS, Chen ZJ, Ronald PC, Marcotte EM.

A pan-plant protein complex map reveals deep conservation and novel assemblies.

Cell. 2020 Mar 16. [Epub ahead of print]

https://www.ncbi.nlm.nih.gov/pubmed/32191846

 

16

Fuller TE, Garabedian PM, Lemonias DP, Joyce E, Schnipper JL, Harry EM, Bates DW, Dalal AK, Benneyan JC.

Assessing the cognitive and work load of an inpatient safety dashboard in the context of opioid management.

Appl Ergon. 2020 May;85:103047.

https://www.ncbi.nlm.nih.gov/pubmed/32174343

Note: The NASA Task Load Index was used.

 

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.