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NASA Spaceline Current Awareness List #900 22 May 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, May 22, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website athttps://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.

 

Papers deriving from NASA support:

 

1

Frings-Meuthen P, Luchitskaya E, Jordan J, Tank J, Lichtinghagen R, Smith SM, Heer M.

Natriuretic peptide resetting in astronauts.

Circulation. 2020 May 12;141(19):1593-5.

https://pubmed.ncbi.nlm.nih.gov/32392103

PI: S.M. Smith

Note: ISS results.

Journal Impact Factor: 23.054

Funding: "The study reported here was funded by the European Space Agency and by institutional funding of the German Aerospace Center. Dr Smith was supported by the Human Health Countermeasures Element of NASA's Human Research Program. Dr Luchitskaya and Dr Tank were supported by the German Aerospace Space Administration (project number 50WB1117 and 50WB1517)."

 

2

Ballerini A, Chua CYX, Rhudy J, Susnjar A, Di Trani N, Jain PR, Laue G, Lubicka D, Shirazi-Fard Y, Ferrari M, Stodieck LS, Cadena SM, Grattoni A.

Counteracting muscle atrophy on Earth and in space via nanofluidics delivery of formoterol.

Adv Ther (Weinh). 2020 May 10. [Article in Press]

https://onlinelibrary.wiley.com/doi/abs/10.1002/adtp.202000014

Note: ISS results; hindlimb unloading was used for ground experiments.

Journal Impact Factor: Not available for this journal

Funding: "A.B. and C.Y.X.C. contributed equally to this work. This work was supported by the ISS National Lab Grant Nos. GA-2016-234, GA-2014-139 T/O #006." Y. Shirazi-Fard is affiliated with NASA Ames Research Center.

 

3

Downs ME, Scott JM, Ploutz-Snyder LL, Ploutz-Snyder R, Goetchius E, Buxton RE, Danesi CP, Randolph KM, Urban RJ, Sheffield-Moore M, Dillon EL.

Exercise and testosterone countermeasures to mitigate metabolic changes during bed rest.

Life Sci Space Res. 2020 May 20. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552420300225

PIs: R.J. Urban, L.L. Ploutz-Snyder

Note: Bed rest study.

Journal Impact Factor: 2.066

Funding: "This study was supported by the NASA Human Research Program, the National Space Biomedical Research Institute (NSBRI) and NASA grant #NNX10AP86G (RJU/MSM) The study was conducted with the support of the Institute for Translational Sciences at the University of Texas Medical Branch through funding by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences, National Institutes of Health. Data were submitted to the NASA Life Science Data Archive (https://lsda.jsc.nasa.gov/)."

 

4

Roberson PA, Shimkus KL, Welles JE, Xu D, Whitsell AL, Kimball EM, Jefferson LS, Kimball SR.

A time course for markers of protein synthesis and degradation with hindlimb unloading and the accompanying anabolic resistance to refeeding.

J Appl Physiol (1985). 2020 May 14. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32407240

Note: Hindlimb unloading study.

Journal Impact Factor: 3.140

Funding: "This work was supported by the National Aeronautics and Space Administration under Grant No. NNX15AK06H issued through the PA Space Grant Consortium (to KL Shimkus). This work was also supported by National Institute of Diabetes and Digestive and Kidney Diseases Grant R01 DK-15658 (to SR Kimball)."

 

5

Ko FC, Mortreux M, Riveros D, Nagy JA, Rutkove SB, Bouxsein ML.

Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats.

npj Microgravity. 2020 May 18;6(1):15.

https://pubmed.ncbi.nlm.nih.gov/32435691

PI: S.B. Rutkove

Note: Hindlimb unloading study. This article may be obtained online without charge.

Journal Impact Factor: 3.111

Funding: "This work was supported by NASA NNX16AL36G."

 

6

Simonsen LC, Slaba TC, Guida P, Rusek A.

NASA's first ground-based galactic cosmic ray simulator: Enabling a new era in space radiobiology research.

PLoS Biol. 2020 May 19;18(5):e3000669.

https://pubmed.ncbi.nlm.nih.gov/32428004

Note: This article may be obtained online without charge.

Journal Impact Factor: 8.386

Funding: "This work was executed under agreements NNJ12HA64I and NNJ16HP161 between NASA and DOE Brookhaven National Laboratory."

 

7

Vimal VP, Zheng H, Hong P, Fakharzadeh LN, Lackner JR, DiZio P.

Characterizing individual differences in a dynamic stabilization task using machine learning.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):479-88.

https://pubmed.ncbi.nlm.nih.gov/32408931

PI: V.P. Vimal, TRISH Postdoctoral Fellowship Program

Journal Impact Factor: 0.889

Funding: "This study was supported through a Synergy Grant from the Translational Research Institute for Space Health through NASA NNX16AO69A. The MARS device was developed under Air Force Office of Scientific Research AFOSR FA9550-12-1-0395."

 

8

Granberry RM, Eschen KP, Ross AJ, Abel JM, Holschuh BT.

Dynamic countermeasure fabrics for post-spaceflight orthostatic intolerance.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):525-31.

https://pubmed.ncbi.nlm.nih.gov/32408937

Journal Impact Factor: 0.889

Funding: "This work was supported by a NASA OTC Space Technology Research Fellowship (grant number 80NSSC17K0158) as well as by MnDRIVE RSAM."

______________________________________________________

 

 

Other papers of interest:

 

1

Ishihara A, Terada M, Kouzaki M, Hagio S, Higashibata A, Yamada S, Furukawa S, Mukai C, Ishioka N.

Blood flow in astronauts on Earth after long space stay.

Acta Astronaut. 2020 May 16. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576520303003

Note: ISS results.

 

2

Geiser F.

Seasonal expression of avian and mammalian daily torpor and hibernation: Not a simple summer-winter affair.

Front Physiol. 2020 May 20;11:436. Review.

https://www.frontiersin.org/article/10.3389/fphys.2020.00436

Note: This article may be obtained online without charge.

 

3

Logan SM, Storey KB.

Regrowth and neuronal protection are key for mammalian hibernation: Roles for metabolic suppression.

Neural Regen Res. 2020 Nov;15(11):2027-8. Review. Epub 2020 May 11.

https://pubmed.ncbi.nlm.nih.gov/32394950

Note: This article may be obtained online without charge.

 

4

Van Puyvelde M, Neyt X, Vanderlinden W, Van den Bossche M, Bucovaz T, De Winne T, Pattyn N.

Voice reactivity as a response to acute hypobaric hypoxia at high altitude.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):471-8.

https://pubmed.ncbi.nlm.nih.gov/32408930

 

5

Haines SR, Siegel JA, Dannemiller KC.

Modeling microbial growth in carpet dust exposed to diurnal variations in relative humidity using the "time-of-wetness" framework.

Indoor Air. 2020 May 13. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32403157

 

6

Amirova L, Navasiolava N, Rukavishvikov I, Gauquelin-Koch G, Gharib C, Kozlovskaya I, Custaud M-A, Tomilovskaya E.

Cardiovascular system under simulated weightlessness: Head-down bed rest vs. dry immersion.

Front Physiol. 2020 May 19;11:395.

https://www.frontiersin.org/article/10.3389/fphys.2020.00395

Note: Head-down tilt bed rest and dry immersion were used. This article may be obtained online without charge.

 

7

Wostyn P, Gibson CR, Mader TH.

Can choroidal engorgement temporarily protect astronauts against optic disc edema?

JAMA Ophthalmol. 2020 May 14. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32407453

Note: The authors comment on: Laurie SS, Lee SMC, Macias BR, Patel N, Stern C, Young M, Stenger MB. Optic disc edema and choroidal engorgement in astronauts during spaceflight and individuals exposed to bed rest. JAMA Ophthalmol. 2019 Dec 26. [Epub ahead of print]https://www.ncbi.nlm.nih.gov/pubmed/31876939, which appeared in SPACELINE Current Awareness List #880, 3 Jan 2020.

 

8

Chauhan V, Stricklin D, Cool D.

The integration of the adverse outcome pathway framework to radiation risk assessment.

Int J Radiat Biol. 2020 May 12. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32397918

 

9

Orekhova NYA.

Hepatic effects of low dose-rate radiation in natural mouse populations (Apodemus uralensis and Apodemus agrarius): Comparative interspecific analysis.

Int J Radiat Biol. 2020 May 15. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32412327

 

10

Ercan E, Gunduz SH.

The effects of acceleration forces on cognitive functions.

Microgravity Sci Technol. 2020 May 19. [Article in Press]

https://link.springer.com/article/10.1007%2Fs12217-020-09793-0

Note: From the abstract: "We investigated the negative effects of acceleration forces on cognitive functions via Time Wall Psychometric Tests which were applied to pilots before and after Human Centrifuge Training."

 

11

Lu T, Lou Z, Shao F, Li Y, You X.

Attention and entropy in simulated flight with varying cognitive loads.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):489-95.

https://pubmed.ncbi.nlm.nih.gov/32408932

Note: From the abstract: "…pilots performed flight tasks in a two-condition (high and low cognitive load) within-subject experiment to compare their flight performance and eye movement indicators."

 

12

Lu Y, Zheng Y, Wang Z, Fu S.

Pilots' visual scanning behaviors during an instrument landing system approach.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):511-7.

https://pubmed.ncbi.nlm.nih.gov/32408935

 

13

Mammarella N.

Towards the affective cognition approach to human performance in space.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):532-4.

https://pubmed.ncbi.nlm.nih.gov/32408938

 

14

Cinelli I.

The role of artificial intelligence (AI) in space healthcare.

Aerosp Med Hum Perform. 2020 Jun 1;91(6):537-9.

https://pubmed.ncbi.nlm.nih.gov/32408941

 

15

Kawamoto N, Kanbe Y, Nakamura M, Mori A, Terao Morita M.

Gravity-sensing tissues for gravitropism are required for "anti-gravitropic" phenotypes of lzy multiple mutants in Arabidopsis.

Plants (Basel). 2020 May 12;9(5):E615.

https://pubmed.ncbi.nlm.nih.gov/32408582

Note: Reorientation was used for gravistimulation. This article may be obtained online without charge.

 

16

Carillo P, Morrone B, Fusco GM, De Pascale S, Rouphael Y.

Challenges for a sustainable food production system on board of the International Space Station: A technical review.

Agronomy. 2020 May 13;10(5):687. Review.

https://www.mdpi.com/2073-4395/10/5/687

Note: This article may be obtained online without charge.

 

17

Paradiso R, Ceriello A, Pannico A, Sorrentino S, Palladino M, Giordano M, Fortezza R, De Pascale S.

Design of a module for cultivation of tuberous plants in microgravity: The ESA Project "Precursor of Food Production Unit" (PFPU).

Front Plant Sci. 2020 May 15;11:417.

https://www.frontiersin.org/article/10.3389/fpls.2020.00417

Note: This article may be obtained online without charge.

 

18

Alford C, Broom C, Carver H, Johnson SJ, Lands S, Reece R, Verster JC.

The impact of alcohol hangover on simulated driving performance during a 'commute to work'—Zero and residual alcohol effects compared.

J Clin Med. 2020 May 12;9(5):E1435.

https://pubmed.ncbi.nlm.nih.gov/32408588

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

 

19

Kneist W, Stein H, Rheinwald M.

Da Vinci single-port robot-assisted transanal mesorectal excision: A promising preclinical experience.

Surg Endosc. 2020 May 11. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32394173

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

// end //

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