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NASA Spaceline Current Awareness List #921 23 October 2020 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, October 23, 2020

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Robyn Ertwine, SPACELINE Current Awareness Senior Editor,SPACELINE@nasaprs.com.

 

 

Papers deriving from NASA support:

 

1

Garrett J, Valluri S, Mendonca MS, Bigsby RM, Lopez J, Caperell-Grant A, Nees J, Dynlacht JR.

The protective effect of estrogen against radiation cataractogenesis is dependent upon the type of radiation.

Radiat Res. 2020 Oct 12. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33045089

PI: J.R. Dynlacht

Journal Impact Factor: 2.657

Funding: "This work was supported by a grant from the National Aeronautics and Space Administration (NNJ05HE64G)."

 

2

Nia AM, Shavkunov A, Ullrich RL, Emmett MR.

137Cs γ ray and 28Si irradiation induced murine hepatocellular carcinoma lipid changes in liver assessed by MALDI-MSI combined with spatial shrunken centroid clustering algorithm: A pilot study.

ACS Omega. 2020 Oct 6;5(39):25164-74.

https://pubmed.ncbi.nlm.nih.gov/33043195

PIs: M.R. Emmett; R.L. Ullrich/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.87

Funding: "This work was supported by the Ground-Based Studies in Space Radiobiology through the National Aeronautics and Space Administration (NASA) NNX15AD65G, NASA Specialized Center of Research (NSCOR) NNX09AM08G and Human Research Program (HRP)."

 

3

Slaba TC, Wilson JW, Werneth CM, Whitman K.

Updated deterministic radiation transport for future deep space missions.

Life Sci Space Res. 2020 Nov;27:6-18.

http://www.sciencedirect.com/science/article/pii/S2214552420300456

Journal Impact Factor: 2.453

Funding: T.C. Slaba and C.M. Werneth are affiliated with NASA Langley Research Center.

 

4

Suman S, Jaruga P, Dizdaroglu M, Fornace AJ Jr, Datta K.

Heavy ion space radiation triggers ongoing DNA base damage by downregulating DNA repair pathways.

Life Sci Space Res. 2020 Nov 27:27-32.

http://www.sciencedirect.com/science/article/pii/S221455242030047X

PIs: K. Datta; A.J. Fornace Jr/K. Datta/NSCOR

Journal Impact Factor: 2.453

Funding: "This study is supported in part by NASA grants NNX13AD58G and NNX09AU95G."

 

5

Wilson JW, Werneth CM, Slaba TC, Badavi FF, Reddell BD, Bahadori AA.

Effects of the Serber First Step in 3DHZETRN-v2.1.

Life Sci Space Res. 2020 Aug;26:10-27.

https://pubmed.ncbi.nlm.nih.gov/32718675

Journal Impact Factor: 2.453

Funding: C.M. Werneth and T.C. Slaba are affiliated with NASA Langley Research Center; B.D. Reddell is affiliated with NASA Johnson Space Center.

 

6

John AR, Raju S, Cadnum JL, Lee K, McClellan P, Akkus O, Miller SK, Jennings WD, Buehler JA, Li DF, Redmond SN, Braskie M, Hoyen CK, Donskey CJ.

Scalable in-hospital decontamination of N95 filtering facepiece respirator with a peracetic acid room disinfection system.

Infect Control Hosp Epidemiol. 2020 Oct 12. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33040749

Note: This article may be obtained online without charge.

Journal Impact Factor: 2.938

Funding: No funding cited. S.K. Miller, W.D. Jennings, and J.A. Buehler are affiliated with NASA Glenn Research Center.

 

7

Torrente-Rodríguez RM, Lukas H, Tu J, Min J, Yang Y, Xu C, Rossiter HB, Gao W.

SARS-CoV-2 RapidPlex: A graphene-based multiplexed telemedicine platform for rapid and low-cost COVID-19 diagnosis and monitoring.

Matter. 2020 Oct 5. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33043291

PI: W. Gao

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This project was supported by the Merkin Institute for Translational Research at Caltech, Emergency COVID-19 Research Seed Funding and COVID-19 Continuation Funding from Tobacco-Related Disease Research Program (TRDRP), TRDRP High Impact Pilot Research Award, National Institutes of Health (5R21NR018271), and the Translational Research Institute through NASA NNX16AO69A. J.T. was supported by the National Science Scholarship from the Agency for Science, Technology and Research (A*STAR), Singapore."

_______________________________________________________

 

 

Other papers of interest:

 

1

Lemelle L, Campagnolo L, Mottin E, Le Tourneau D, Garre E, Marcoux P, Thévenot C, Maillet A, Barde S, Teisseire J, Nonglaton G, Place C.

Towards a passive limitation of particle surface contamination in the Columbus module (ISS) during the MATISS experiment of the Proxima Mission.

npj Microgravity. 2020 Oct 20;6(1):29.

https://www.nature.com/articles/s41526-020-00120-w

Note: ISS results. This article may be obtained online without charge.

 

2

Buchheim JI, Ghislin S, Ouzren N, Albuisson E, Vanet A, Matzel S, Ponomarev S, Rykova M, Choukér A, Frippiat JP.

Plasticity of the human IgM repertoire in response to long-term spaceflight.

FASEB J. 2020 Oct 13. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33047384

Note: ISS results. This article may be obtained online without charge.

 

3

Buynov LG, Blaguinin АА, Glaznikov LA, Sorokina LА.

[Study of the effectiveness of normal and low-pressure hypoxic training in optimization of the functional state and improvement of professional fitness of people controlling high-speed vehicles].

Aviakosm Ekolog Med. 2020;54(1):57-63. Russian.

https://elibrary.ru/item.asp?id=42497658

 

4

Ward K, Mulder E, Frings-Meuthen P, O'Gorman DJ, Cooper DA.

Fetuin-A as a potential biomarker of metabolic variability following 60 days of bed rest.

Front Physiol. 2020 Oct 19;11:1297.

https://www.frontiersin.org/article/10.3389/fphys.2020.573581

Note: Head-down tilt bed rest study. This article may be obtained online without charge.

 

5

Kashirina DN, Kononikhin AS, Ratushnyy AY, Nikolaev EN, Larina IM, Buravkova LB.

Proteomic profile of cultured human endothelial cells after exposition to simulated microgravity.

Acta Astronaut. 2020 Oct 15. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S0094576520306093

Note: A Random Positioning Machine was used.

 

6

Kim HW, Rhee MS.

Space food and bacterial infections: Realities of the risk and role of science.

Trends Food Sci Technol. 2020 Dec 1;106:275-87. Epub 2020 Oct 15.

http://www.sciencedirect.com/science/article/pii/S0924224420306464

 

7

Rudenko ЕА, Cherepov AB, Baranov MV, Lebedeva МА, Khlebnikova NN.

[Studies of cardiovascular system autonomic regulation during extended exposure to horizontal and tilted bed rest and head-down tilt bed rest].

Aviakosm Ekolog Med. 2020;54(1):31-7. Russian.

https://elibrary.ru/item.asp?id=42497654

Note: Head-down tilt bed rest study.

 

8

Ilyin VK, Rykova MP, Antropova EN, Solovieva ZO, Nosovsky АМ.

[Investigation of parodontium tissue during microgravity factor modelling].

Aviakosm Ekolog Med. 2020;54(1):79-83. Russian.

https://elibrary.ru/item.asp?id=42497662

Note: Dry immersion study.

 

9

Lima-Silveira L, Martinez D, Hasser EM, Kline DD.

Mechanisms underlying neuroplasticity in the nucleus tractus solitarii following hindlimb unloading in rats.

Neuroscience. 2020 Oct 8. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33039526

Note: Hindlimb unloading study.

 

10

Augat P, Hollensteiner M, von Rüden C.

The role of mechanical stimulation in the enhancement of bone healing.

Injury. 2020 Oct 2. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33041020

 

11

Shafirkin AV.

[New outlook for the space radiation risks paradigm for remote beyond-magnetosphere missions to the Moon and Mars].

Aviakosm Ekolog Med. 2020;54(1):5-15. Russian.

https://elibrary.ru/item.asp?id=42497651

 

12

Shtemberg AS, Klots IN, Belyaeva AG, Blokhina TM, Yashkina EI, Osipov AN, Bazyan AS, Kudrin VS, Perevezentsev АА, Koshlan NA, Bogdanova YV, Koshlan IV, Timoshenko GN, Lapin BA. 

[Hematological, biochemical and molecular effects of primate's head irradiation with high-energy krypton nuclei].

Aviakosm Ekolog Med. 2020;54(1):38-45. Russian.

https://elibrary.ru/item.asp?id=42497655

 

13

Shuryak I, Ghandhi SA, Turner HC, Weber W, Melo D, Amundson SA, Brenner DJ.

Dose and dose-rate effects in a mouse model of internal exposure from 137Cs. Part 2: Integration of γ-H2AX and gene expression biomarkers for retrospective radiation biodosimetry.

Radiat Res. 2020 Oct 16. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33064820

 

14

Yasnetsov VV, Ivanov YV, Karsanova SК, Yasnetsov VV.

[Effect of melatonin combined with 3-hydroxypyridine derivatives on neurons of the lateral vestibular nucleus and cerebellum cortex in animals].

Aviakosm Ekolog Med. 2020;54(1):69-74. Russian.

https://elibrary.ru/item.asp?id=42497660

 

15

Choukér A, Stahn AC.

COVID-19—The largest isolation study in history: The value of shared learnings from spaceflight analogs.

npj Microgravity. 2020 Oct 22;6(1):32.

https://www.nature.com/articles/s41526-020-00122-8

Note: From the Introduction: "Here, we summarize the opportunities of spaceflight analogs to accelerate (1) the understanding of the neurobehavioral and immunological consequences of social isolation during the COVID-19 pandemic, and (2) the development of innovative and efficient treatment strategies to mitigate adverse behavioral conditions." This article may be obtained online without charge.

 

16

Fomina EV, Kussmaul AR, Belakovskiy MS.

[Biomedical problems of human space exploration, on the materials of the 22nd Humans in Space Symposium of the International Academy of Astronautics].

Aviakosm Ekolog Med. 2020;54(1):84-91. Russian.

https://elibrary.ru/item.asp?id=42497663

 

17

Nakushian A, Deaton JE.

Issues facing crew selection for long duration space flight missions.

Int J Aviat Res. 2020;12(1):20-34.

https://ojs.library.okstate.edu/osu/index.php/IJAR/article/view/8081

Note: Topics discussed include the history of astronaut selection in the United States, current astronaut selection criteria, crew personality and psychology, crew medical factors, crew training, and gaps in and future directions of research. This article may be obtained online without charge.

 

18

Stepanova SI, Koroleva MV, Karapetyan AS, Galichiy VА, Karpova ОI.

[Theoretical and applied aspects of work and rest scheduling for members of missions according to the Russian Lunar program].

Aviakosm Ekolog Med. 2020;54(1):23-30. Russian.

https://elibrary.ru/item.asp?id=42497653

 

19

Sayapin SN.

[Analysis and prospective use of autonomous symbiotic self-relocating body massage robot "TRIANGEL" onboard piloted space stations].

Aviakosm Ekolog Med. 2020;54(1):75-8. Russian.

https://elibrary.ru/item.asp?id=42497661

 

20

Farooq M, Jan R, Kim KM.

Gravistimulation effects on Oryza sativa amino acid profile, growth pattern and expression of OsPIN genes.

Sci Rep. 2020 Oct 14;10(1):17303.

https://pubmed.ncbi.nlm.nih.gov/33057095

Note: Petri dish orientation was used for gravistimulation. This article may be obtained online without charge.

 

21

Oluwafemi FA, Ibraheem O, Fatoki TH.

Clinostat microgravity impact on root morphology of selected nutritional and economic crops.

Plant Cell Biotechnol Mol Biol. 2020;21(43-44):92-104.

https://ikprress.org/index.php/PCBMB/article/view/5478

Note: A clinostat was used. This article may be obtained online without charge.

 

22

Zhu M, Hu Y, Tong A, Yan B, Lv Y, Wang S, Ma W, Cui Z, Wang X.

LAZY1 controls tiller angle and shoot gravitropism by regulating the expression of auxin transporters and signaling factors in rice.

Plant Cell Physiol. 2020 Oct 17. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33067639

 

23

Cohen-Lazry G, Borowsky A.

Improving drivers' hazard perception and performance using a less visually-demanding interface.

Front Psychol. 2020 Oct 13;11:2216.

https://pubmed.ncbi.nlm.nih.gov/33041892

Note: The NASA Raw Task Load Index was used. This article may be obtained online without charge.

 

24

Kennedy-Metz LR, Wolfe HL, Dias RD, Yule SJ, Zenati MA.

Surgery Task Load Index in cardiac surgery: Measuring cognitive load among teams.

Surg Innov. 2020 Jun 17. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/32938323

Note: From the Introduction: "In an effort to generate a surgery-specific cognitive load measure, the surgery task load index (SURG-TLX) was developed and validated. The SURG-TLX scale presents a similar format as the NASA-TLX but substitutes 3 of the cognitive load dimensions with domains more relevant to surgical tasks."

 

25

Zoaktafi M, Zakerian SA, Choobineh A, Nematolahi S, Kazemi R.

Relationship between mental workload and salivary cortisol levels: A field study.

Work. 2020 Oct 9. [Epub ahead of print]

https://pubmed.ncbi.nlm.nih.gov/33044218

Note: The NASA Task Load Index was used.

// end //

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