Note:ISS results. From the article: "This case study was taken from a convenience sample during a recent ISS mission (both preflight preparation for the mission and in flight) and examined different angles of tilt as well as comparing terrestrial and orbital physiology using a long-established Russian training protocol."
Journal Impact Factor:0.954
Funding:No funding cited. R.A. Scheuring and A. Morgan are affiliated with NASA Johnson Space Center.
Note:ISS results. From the abstract: "We report posterior GF in three astronauts that has persisted for 7 years or more following their return from LDSFs suggesting that permanent scleral remodeling may have occurred."
Journal Impact Factor:0.184
Funding:No funding cited. M.R. Barratt, W.J. Tarver, A.E. Sargsyan, and T.J. Brunstetter are affiliated with NASA Johnson Space Center.
Jaramillo-Botero A, Cable ML, Hofmann AE, Malaska M, Hodyss R, Lunine J.
Understanding hypervelocity sampling of biosignatures in space missions.
Note:This article may be obtained online without charge.
Journal Impact Factor:4.091
Funding:"This work was performed at the California Institute of Technology and the Jet Propulsion Laboratory (JPL), California Institute of Technology, under contract with the National Aeronautics and Space Administration - NASA (80NM0018D0004)."
MacNamara JP, Dias KA, Sarma S, Lee SMC, Martin D, Romeijn M, Zaha VG, Levine BD.
Cardiac effects of repeated weightlessness during extreme duration swimming compared with spaceflight.
Circulation. 2021 Mar 29. Research Letter. Online ahead of print.
Funding:"The authors acknowledge the many people at the National Aeronautics and Space Administration, The Longest Swim, and the Institute for Exercise and Environmental Medicine for supporting these unprecedented human achievements."
Britten RA, Wellman LL, Sanford LD.
Progressive increase in the complexity and translatability of rodent testing to assess space-radiation induced cognitive impairment.
Neurosci Biobehav Rev. 2021 Mar 22;126:159-74. Review.
PIs:R.A. Britten, L.D. Sanford, C. Limoli/R.A. Britten/NSCOR
Note:From the abstract: "This review outlines technical and conceptual advances in space radiation rodent testing approaches, along with the advances in analytical approaches, that will make data from ground based studies more amenable to probabilistic risk analysis."
Journal Impact Factor:8.330
Funding:"The authors gratefully acknowledge the past and present grant support from NASA that made our work possible (80NSSC19K1582, NNX16AC40G, NNX15AI22G, NNX14AE73G, NNX11AC56G, NNJ06HD89G)."
Voros JL, Sherman SO, Rise R, Kryuchkov A, Stine P, Anderson AP, Clark TK.
Galvanic vestibular stimulation produces cross-modal improvements in visual thresholds.
Front Neurosci. 2021 Mar 31;15(311):640984. This article may be obtained online without charge.
Note:From the abstract: "This study is a retrospective cohort study involving secondary analysis of data stored in the NASA Lifetime Surveillance of Astronaut Health Repository. Multivariable analysis was performed to evaluate the impact of protein intake on physical performance by considering covariates potentially associated with each model."
Journal Impact Factor:0.889
Funding:"The authors are grateful to the study subjects for their involvement in the study. This work was supported by a NASA cooperative agreement."
Note:ISS results. From the abstract: "The first skin physiological pilot experiment (SkinA) on a single astronaut showed a deterioration of the skin. In a follow-up experiment (SkinB) we showed that skin physiological parameters improved on average. However, it is well known that sports have positive effects on the skin, that astronauts prefer special sports devices, and do sports with different intensity. The aim of this study was to analyze the different sports activities of SkinB astronauts and to find out whether they have an influence on the skin physiological parameters."
Electrical shock hazard severity estimation during extravehicular activity for the International Space Station.
Note:From the abstract: "This study used computer models to determine whether these undesired induced electrical currents could be responsible for involuntary neuromuscular activity caused by either large diameter peripheral nerve activation or reflex activity from cutaneous afferent stimulation."
Zamarioli A, Campbell ZR, Maupin KA, Childress PJ, Ximenez JPB, Adam G, Chakraborty N, Gautam A, Hammamieh R, Kacena MA.
Analysis of the effects of spaceflight and local administration of thrombopoietin to a femoral defect injury on distal skeletal sites.
Note:ISS results. From the abstract: "Here, we investigated the systemic effects of TPO on mice subjected to spaceflight and sustaining a bone fracture." This article may be obtained online without charge.
Aerospace medicine research: The division of environmental physiology and the Swedish Aerospace Physiology Centre.
Note:Author DeJohn, President of the Aerospace Medical Association, provides information from the Division of Environmental Physiology and the Swedish Aerospace Physiology Centre, including the history and research being performed in naval medicine and thermal and exercise physiology research, in addition to aviation and space medicine research for the European Space Agency, European Union, and industry.
Liu ZF, Wang HM, Jiang M, Wang L, Lin LJ, Zhao YZ, Shao JJ, Zhou JJ, Xie MJ, Li X, Zhang R.
Mitochondrial oxidative stress enhances vasoconstriction by altering calcium homeostasis in cerebrovascular smooth muscle cells under simulated microgravity.
Note:A random positioning machine and rotating wall vessel were used. From the abstract: "The present results suggest that mitochondrial oxidative stress enhances cerebral vasoconstriction by regulating calcium homeostasis during simulated microgravity." This article may be obtained online without charge.
Kharlamova A, Proshchina A, Gulimova V, Krivova Y, Soldatov P, Saveliev S.
Cerebellar morphology and behavioural correlations of the vestibular function alterations in weightlessness.
Neurosci Biobehav Rev. 2021 Mar 22;S0149-7634(21)00124-X. Review. Online ahead of print.
Note:From the abstract: "Support for the role of gravity in aging has mostly come from ground simulation studies in head down bed rest. However, uncertainties remain and have to be resolved in planning for the ambitious enterprise of sending humans to Mars and back. Stress-related corticosteroid changes and metabolic adaptation to microgravity and their relationship with aging are the object of the present review mostly, albeit of course non exclusively, coming from the personal experience of the authors." J. Vernikos was affiliated with NASA Headquarters.
Ånell R, Grönkvist M, Gennser M, Eiken O.
Hyperoxic effects on decompression strain during alternating high and moderate altitude exposures.
Note:From the abstract: "In fighter aircraft, long-duration high-altitude sorties are typically interrupted by refueling excursions to lower altitude. In normoxia, excursions to moderate cabin altitude may increase the occurrence of venous gas emboli (VGE) at high cabin altitude. The aim was to investigate the effect of hyperoxia on VGE and decompression sickness (DCS) during alternating high and moderate altitude exposure."