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NASA Spaceline Current Awareness List # 960 30 July 2021 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, July 30, 2021

SPACELINE Current Awareness Lists are distributed via listserv and are available on the NASA Task Book website at https://taskbook.nasaprs.com/Publication/spaceline.cfm. Please send any correspondence to Shawna Byrd, SPACELINE Current Awareness Senior Editor, SPACELINE@nasaprs.com.
 
Papers deriving from NASA support:
 
1
Lee JK, Koppelmans V, Pasternak O, Beltran NE, Kofman IS, De Dios YE, Mulder ER, Mulavara AP, Bloomberg JJ, Seidler RD.
Effects of spaceflight stressors on brain volume, microstructure, and intracranial fluid distribution.
Cereb Cortex Commun. 2021 Mar 30;2(2):tgab022.
https://pubmed.ncbi.nlm.nih.gov/34296167
PI: R.D. Seidler
Note: Head-down tilt bed rest study. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: "NASA (#80NSSC17K0021, NSBRI SA02802)."
 
2
Juhl OJ 4th, Buettmann EG, Friedman MA, DeNapoli RC, Hoppock GA, Donahue HJ.
Update on the effects of microgravity on the musculoskeletal system.
npj Microgravity. 2021 Jul 23;7(1):28. Review.
https://pubmed.ncbi.nlm.nih.gov/34301942
PIs: H.J. Donahue; E.G. Buettmann, M.A. Friedman, TRISH Postdoctoral Fellowship Program
Note: ISS, Shuttle, Foton results. From the introduction: "The objective of this article is to review the current knowledge developed over the past decade regarding how real and simulated microgravity affects the cellular and physiological function of the musculoskeletal system." This article may be obtained online without charge.
Journal Impact Factor: 4.415
Funding: "Drs. Friedman and Buettmann were supported by the Translational Research Institute through Cooperative Agreement NNX16AO69A. Dr. Donahue’s work was supported by NIH (NIAMS) grant R01 AR068132-20, NASA grant 80NSSC18K1473, and National Space Biological Research Institute grant NSBRI/NASA, MA02802."
 
3
Minnier J, Emmett MR, Perez R, Ding LH, Barnette BL, Larios RE, Hong C, Hwang TH, Yu Y, Fallgren CM, Story MD, Weil MM, Raber J.
Associations between lipids in selected brain regions, plasma miRNA, and behavioral and cognitive measures following 28Si ion irradiation.
Sci Rep. 2021 Jul 21;11(1):14899.
https://pubmed.ncbi.nlm.nih.gov/34290258
PIs: M.M. Weil/M.R. Emmett/T.H. Hwang/M.D. Story/J. Raber/NSCOR
Note: This article may be obtained online without charge.
Journal Impact Factor: 3.998
Funding: "This work was supported by NASA NSCOR Grant NNX15AK13G."
 
4
Tidmore A, Dutta SM, Fesshaye AS, Russell WK, Duncan VD, Britten RA.
Space radiation-induced alterations in the hippocampal ubiquitin-proteome system.
Int J Mol Sci. 2021 Jul 19;22(14):7713.
https://pubmed.ncbi.nlm.nih.gov/34299332
PI: R.A. Britten
Note: This article is part of Special Issue "Ubiquitination in Health and Diseases: Volume II" (https://www.mdpi.com/journal/ijms/special_issues/ubiquitination_health_vol2). Additional articles will be forthcoming and may be found in the link to the Special Issue. This article may be obtained online without charge.
Journal Impact Factor: 4.556
Funding: "This work was funded by NASA grant support NNX11AC56G and NNX14AE73G."
 
5
Langenfeld NJ, Kusuma P, Wallentine T, Criddle CS, Seefeldt LC, Bugbee B.
Optimizing nitrogen fixation and recycling for food production in regenerative life support systems.
Front Astron Space Sci. 2021 Jun 18;8:699688. Review.
https://doi.org/10.3389/fspas.2021.699688
Note: This article and the articles listed below in the "Other" section (starting with Fahrion et al. through the end of the CA List) are part of Research Topic "Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars" (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). Additional articles may be found in the link to the Research Topic. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: "This research was supported by the Utah Agricultural Experiment Station, Utah State University, and approved as journal paper number 9465; the NASA-CUBES (Grant Number NNX17AJ31G)."
 
_______________________________________________________
 
 
Other papers of interest:
 
1
Otsuka K, Cornelissen G, Furukawa S, Kubo Y, Shibata K, Mizuno K, Ohshima H, Mukai C.
Astronauts well-being and possibly anti-aging improved during long-duration spaceflight.
Sci Rep. 2021 Jul 21;11(1):14907.
https://pubmed.ncbi.nlm.nih.gov/34290387
Note: ISS results. From the abstract: "This study assesses how circadian rhythms of heart rate (HR), HR variability (HRV) and activity change during long-term missions in space and how they relate to sleep quality." This article may be obtained online without charge.
 
2
Yoshida K, Fujita SI, Isotani A, Kudo T, Takahashi S, Ikawa M, Shiba D, Shirakawa M, Muratani M, Ishii S.
Intergenerational effect of short-term spaceflight in mice.
iScience. 2021 Jul 23;24(7):102773.
https://pubmed.ncbi.nlm.nih.gov/34278272
Note: ISS results. From the abstract: "Here we investigated the effect of 35 days spaceflight on male germ cells." This article may be obtained online without charge.
 
3
Zeng D, Cui J, Yin Y, Xiong Y, Liu M, Guan S, Cheng D, Sun Y, Lu W.
Metabolomics analysis in different development stages on SP0 generation of rice seeds after spaceflight.
Front Plant Sci. 2021 Jun 30;12:700267.
https://pubmed.ncbi.nlm.nih.gov/34276752
Note: China's ShiJian-10 recoverable satellite results. This article may be obtained online without charge.
 
4
Cheng L, Silva P, Dahab R.
Dysbaric osteonecrosis of the humeral head in a patient with type 2 decompressive sickness.
Spinal Cord Ser Cases. 2021 Jul 21;7(1):62.
https://pubmed.ncbi.nlm.nih.gov/34290228
 
5
Ogneva IV.
Mouse and fly sperm motility changes differently under modelling microgravity.
Curr Issues Mol Biol. 2021 Jul 5;43(2):590-604.
https://pubmed.ncbi.nlm.nih.gov/34287235
Note: A random positioning machine was used in this study. This article belongs to the Section "Biochemistry, Molecular and Cellular Biology Section" (https://www.mdpi.com/journal/cimb/sections/BMCB). The Section also includes an article from a previous Current Awareness List #953 https://doi.org/10.3390/cimb43010015. Additional articles may be found in the link to the Section. This article may be obtained online without charge.
 
6
Salatino A, Iacono C, Gammeri R, Chiadò ST, Lambert J, Sulcova D, Mouraux A, George MS, Roberts DR, Berti A, Ricci R.
Zero gravity induced by parabolic flight enhances automatic capture and weakens voluntary maintenance of visuospatial attention.
npj Microgravity. 2021 Jul 27;7(1):29.
https://pubmed.ncbi.nlm.nih.gov/34315902
Note: Parabolic flight results. This article may be obtained online without charge.
 
7
Zhang H, Wang Y, Zhang Z, Zhang L, Tang C, Sun B, Jiang Z, Ding B, Cai P.
Alterations in the activity and sleep of Drosophila melanogaster under simulated microgravity.
npj Microgravity. 2021 Jul 22;7(1):27.
https://pubmed.ncbi.nlm.nih.gov/34294729
Note: A random positioning machine was used in this study. This article may be obtained online without charge.
 
8
Hagio S, Nakazato M, Kouzaki M.
Modulation of spatial and temporal modules in lower limb muscle activations during walking with simulated reduced gravity.
Sci Rep. 2021 Jul 20;11(1):14749.
https://pubmed.ncbi.nlm.nih.gov/34285306
Note: A vertical body weight support system was used in this study. This article may be obtained online without charge.
 
9
Choi RB, Robling AG.
The Wnt pathway: An important control mechanism in bone's response to mechanical loading.
Bone. 2021 Dec;153:116087. Review.
https://pubmed.ncbi.nlm.nih.gov/34271473
Note: This article is part of Special Issue "Bone Mechanobiology" (https://www.sciencedirect.com/journal/bone/special-issue/10QDVZWKDMW). The Special Issue also includes articles from previous Current Awareness Lists #952 https://doi.org/10.1016/j.bone.2021.116019 and #954 https://doi.org/10.1016/j.bone.2021.116032. Additional articles may be found in the link to the Special Issue and others may be forthcoming.
 
10
Schmal Z, Hammer B, Müller A, Rübe CE.
Fractionated low-dose radiation induces long-lasting inflammatory responses in the hippocampal stem cell niche.
Int J Radiat Oncol Biol Phys. 2021 Jul 16;S0360-3016(21)00877-4. Online ahead of print.
https://pubmed.ncbi.nlm.nih.gov/34280471
 
11
Bradke BS, Miller TA, Everman B.
Photoplethysmography behind the ear outperforms electrocardiogram for cardiovascular monitoring in dynamic environments.
Sensors (Basel). 2021 Jul 2;21(13):4543.
https://pubmed.ncbi.nlm.nih.gov/34283086
Note: This article belongs to the Collection "Medical Applications of Sensor Systems and Devices" (https://www.mdpi.com/journal/sensors/special_issues/MASSD). Additional articles may be found in the link to the Collection. This article may be obtained online without charge.
 
The following articles and the article listed above in the "NASA" section (Langenfeld et al.) are part of Research Topic "Bioregenerative Life-Support Systems for Crewed Missions to the Moon and Mars" (https://www.frontiersin.org/research-topics/16705/bioregenerative-life-support-systems-for-crewed-missions-to-the-moon-and-mars#articles). Additional articles may be found in the link to the Research Topic.
 
12
Fahrion J, Mastroleo F, Dussap CG, Leys N.
Use of photobioreactors in regenerative life support systems for human space exploration.
Front Microbiol. 2021 Jun 29;12:699525. Review.
https://pubmed.ncbi.nlm.nih.gov/34276632
Note: An overview of experiments conducted in low-Earth orbit with photobioreactors and the precursor work for bioregenerative life support systems projects over the last 30 years are presented in this article. This article may be obtained online without charge.
 
13
Averesch NJH.
Choice of microbial system for in-situ resource utilization on Mars.
Front Astron Space Sci. 2021 Jun 30;8:700370.
https://doi.org/10.3389/fspas.2021.700370
Note: This article may be obtained online without charge.
 
14
Berliner AJ, Hilzinger JM, Abel AJ, McNulty MJ, Makrygiorgos G, Averesch NJH, Sen Gupta S, Benvenuti A, Caddell DF, Cestellos-Blanco S, Doloman A, Friedline S, Ho D, Gu W, Hill A, Kusuma P, Lipsky I, Mirkovic M, Luis Meraz J, Pane V, Sander KB, Shi F, Skerker JM, Styer A, Valgardson K, Wetmore K, Woo S-G, Xiong Y, Yates K, Zhang C, Zhen S, Bugbee B, Clark DS, Coleman-Derr D, Mesbah A, Nandi S, Waymouth RM, Yang P, Criddle CS, McDonald KA, Seefeldt LC, Menezes AA, Arkin AP.
Towards a biomanufactory on Mars.
Front Astron Space Sci. 2021 Jul 19;8:711550.
https://doi.org/10.3389/fspas.2021.711550
Note: This article may be obtained online without charge.
 
15
Cestellos-Blanco S, Friedline S, Sander KB, Abel AJ, Kim JM, Clark DS, Arkin AP, Yang P.
Production of PHB from CO2-derived acetate with minimal processing assessed for space biomanufacturing.
Front Microbiol. 2021 Jul 28;12:700010.
https://doi.org/10.3389/fmicb.2021.700010
Note: This article may be obtained online without charge.
 
16
Detrell G.
Chlorella vulgaris photobioreactor for oxygen and food production on a Moon base—Potential and challenges.
Front Astron Space Sci. 2021 Jul 23;8:700579. Review.
https://doi.org/10.3389/fspas.2021.700579
Note: This article may be obtained online without charge.
 
17
Przybyla C.
Space aquaculture: Prospects for raising aquatic vertebrates in a bioregenerative life-support system on a lunar base.
Front Astron Space Sci. 2021 Jun 24;8:699097. Review.
https://doi.org/10.3389/fspas.2021.699097
Note: This article may be obtained online without charge.
 

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