In case you missed it:SpaceRefwebsite ran an article titled, "NASA Space Station On-Orbit Status Report 10 January, 2021 - Space Agriculture," providing a status report of the many on-orbit agriculture studies that are currently being conducted. From the article: "Growing plants in space is critical to keeping crews healthy as NASA and its international partners plan human missions to the Moon, Mars and beyond. Just like humans living in space, microgravity affects plants and scientists want to learn how to successfully grow crops in space to sustain crews with less support from Earth." To view the full article go tohttp://spaceref.com/international-space-station/nasa-space-station-on-orbit-status-report-10-january-2021--.html.
Papers deriving from NASA support:
Martin D, Makedonas G, Crucian B, Peanlikhit T, Rithidech K.
The use of the Multidimensional Protein Identification Technology (MudPIT) to analyze plasma proteome of astronauts collected before, during, and after spaceflights.
Note:From the abstract: "The Spacecraft Maximum Allowable Concentrations (SMACs) for C2-C9 alkanes set by NASA in 2008 under the guidance and approval of the National Research Council specifically excluded SMACs for n-hexane. Unlike other C2-C9 alkanes, n-hexane can cause polyneuropathy after metabolism in humans or rodents and so requires more stringent SMACs than the other members of this group do. This document reviews the relevant published studies of n-hexane toxicity to develop exposure duration-specific SMACs for n-hexane of 200 ppm for 1 hour, 30 ppm for 24 hours, and 2.4 ppm for 7 days, 30 days, 180 days, and 1000 days."
Journal Impact Factor:0.889
Funding:"This study was supported by Toxicology, Human Health and Performance Contract #NNJ15HK11B, KBR, NASA Johnson Space Center, Houston, TX, USA."
Diaz-Artiles A, Wang Y, Davis MM, Abbott R, Keller N, Kennedy DM.
The influence of altered-gravity on bimanual coordination: Retention and transfer.
Note:From the abstract: "As we aim to expand human presence in space, we need to find viable approaches to achieve independence from terrestrial resources. Space biomining of the Moon, Mars and asteroids has been indicated as one of the promising approaches to achieve in-situ resource utilization by the main space agencies. Structural and expensive metals, essential mineral nutrients, water, oxygen and volatiles could be potentially extracted from extraterrestrial regolith and rocks using microbial-based biotechnologies. The use of bioleaching microorganisms could also be applied to space bioremediation, recycling of waste and to reinforce regenerative life support systems." This article may be obtained online without charge.
Journal Impact Factor:2.395
Funding:"Rosa Santomartino and Charles S. Cockell were supported by United Kingdom Science and Technology Facilities Council under grants ST/R000875/1 and ST/V000586/1. Luis Zea was supported by the National Aeronautics and Space Administration under Grant No. 80NSSC18K1486, by BioServe Space Technologies, and by the University of Colorado Boulder’s Research Innovation Ofce (RIO) Seed Grant funding."
Tolsma J, Ryan K, Torres J, Richards J, Richardson Z, Land E, Perera I, Doherty C.
The circadian-clock regulates theArabidopsisgravitropicresponse.
Note:This article may be obtained online without charge.
Journal Impact Factor:Not available for this journal
Funding:"Funding was made possible for this work from NASA 80NSSC18K1466. We would like to thank Anna Maria J Ruby, Simon Gilroy, the Microgravity Simulation Support Facility, and Kennedy Space Center staff for their assistance and technical knowledge during the RPM experiments. Jigar Desai and Tomas Pierce helped teach the basics of raspbian and Grant Scarboro provided expertise in optics and imaging."
Shuryak I, Loucas BD, Cornforth MN.
Robbing Peter to pay Paul: Competition for radiogenic breaks during rejoining diminishes curvature in the dose response for simple chromosome exchanges.
Funding:"This work supported by the National Aeronautics and Space Administration (NASA grant nos. NNX15AG74G to MC and 80NSSC18K0864 to BL) and the National Institute of Allergy and Infectious Diseases (NIAID grant no. 2U19AI067773-16 to IS)."
Yamazaki EM, Rosendahl-Garcia KM, Casale CE, MacMullen LE, Ecker AJ, Kirkpatrick JN, Goel N.
Left ventricular ejection time measured by echocardiography differentiates neurobehavioral resilience and vulnerability to sleep loss and stress.
Funding:"This work was supported by National Aeronautics and Space Administration (NASA) [grant numbers NNX14AN49G and 80NSSC20K0243 (to NG)]. This work was also partially supported from National Institutes of Health [grant number NIH R01DK117488 (to NG)]."
Note:From the abstract: "In this mini review, we focus on the International Space Station (ISS) as the only current human habitat in space that has a diverse range of viral genera that infect microorganisms from bacteria to eukaryotes. Thus, we have reviewed the literature on the physical conditions of space habitats that have an impact on both virus transmissibility and interaction with their host, which include UV radiation, ionizing radiation, humidity, and microgravity." This article may be obtained online without charge.
Cordasco KM, Watson T, Glassman P.
When lightning hits your spaceship: The power and peril of habits in aerospace and patient safety.
J Gen Intern Med. 2022 Jan 3;1-3. Online ahead of print.
Note:From the abstract: "This model was firstly validated by using experimental data from experiment of posture change and centrifuge tests of +Gz accelerations, and then applied to analyze human hemodynamic responses to typical multi-axial accelerations."
Ma L, Kong F, Sun K, Wang T, Guo T.
From classical radiation to modern radiation: Past, present, and future of radiation mutation breeding.
Front Public Health. 2021 Dec 21;9:768071. Review.
Note:From the abstract: "Silicon nitride (SiN [Si3N4]) is a promising bioceramic for use in a wide variety of orthopedic applications. Over the past decades, it has been mainly used in industrial applications, such as space shuttle engines, but not in the medical field due to scarce data on the biological effects of SiN. More recently, it has been increasingly identified as an emerging material for dental and orthopedic implant applications. Although a few reports about the antibacterial properties and osteoconductivity of SiN have been published to date, there have been limited studies of SiN-based scaffolds for bone tissue engineering. Here, we developed a silicon nitride reinforced gelatin/chitosan cryogel system (SiN-GC) by loading silicon nitride microparticles into a gelatin/chitosan cryogel (GC), with the aim of producing a biomimetic scaffold with antibiofilm and osteogenic properties." This article may be obtained online without charge.
Wang B, Wang H, Li Y, Song L.
Lipid metabolism within the bone micro-environment is closely associated with bone metabolism in physiological and pathophysiological stages.
Note:From the abstract: "This is a case study of the implementation of a data and analytics-enabled Mission Control at one of the largest healthcare service providers in the state of Washington. Using data analytics and artificial intelligence, CHI-Franciscan (one of the largest healthcare organizations in state of Washington) is able to coordinate patient care more effectively and efficiently, improving safety for all its patients. This case study demonstrates tangible evidence from quantitative and qualitative analysis for return on investment for such a large project." This article may be obtained online without charge.
Jiong Guo J, Du J, Xu Y, Liu A, Yang HL.
Catching the circadian rhythm of intervertebral disc and association with clinical outcomes by twice-a-day magnetic resonance imaging.