NASA Spaceline 28 September 2007 Current Space Life Science Awareness


The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Wilson JW, Ott CM, Höner zu Bentrup K, Ramamurthy R, Quick L, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Fernandez D, Richter E, Shah M, Kilcoyne M, Joshi L, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, Goulart C, Rupert M, Stodieck L, Stafford P, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Allen P, Baker-Coleman C, Hammond T, Vogel J, Nelson R, Pierson DL, Stefanyshyn-Piper HM, Nickerson CA. Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. Proc Natl Acad Sci U S A. 2007 Sep 27; [Epub ahead of print] (PI: C.A. Nickerson) Note: STS-115 results. This significant paper received widespread media coverage; for a sample, search the name Cheryl Nickerson on Google News. The Washington Post article was on the top of page 3 of the Post.
  2. Adams GR, Haddad F, Bodell PW, Tran PD, Baldwin KM. Combined isometric, concentric and eccentric resistance exercise prevents unloading induced muscle atrophy in rats. J Appl Physiol. 2007 Sep 13; [Epub ahead of print] (PI: K.M. Baldwin) Note: Summary, from paper: "The results of the current study indicate that a resistance exercise protocol that combines isometric, concentric and eccentric modes of contraction with an accumulated volume of training greater than that reported in our previous study, results in a suppression of catabolic signaling (myostatin) and the maintenance of anabolic processes such that the muscle atrophy response to unloading can be effectively blunted."
  3. Yang Y, Baker MJ, Graf SC, Larson JK, Caiozzo VJ. Hypergravity resistance exercise: The use of artificial gravity as potential countermeasure to microgravity. J Appl Physiol. 2007 Sep 13; [Epub ahead of print] (PI: V.J. Caiozzo)
  4. Ramsey MW, Behnke BJ, Prisby RD, Delp MD. Effects of aging on adipose resistance artery vasoconstriction: Possible implications for orthostatic blood pressure regulation. J Appl Physiol. 2007 Sep 20; [Epub ahead of print] (PI: M.D. Delp) Note: From conclusion in paper: "This diminished vasoconstrictor response of white adipose tissue coupled with the increased percentage of body fat with old age (reference provided) provides a clinically relevant mechanism that may contribute to the orthostatic hypotension that is prevalent among the elderly."
  5. Triplett JW, O'Riley R, Tekulve K, Norvell SM, Pavalko FM. Mechanical loading by fluid shear stress enhances IGF-1 receptor signaling in osteoblasts in a PKCzeta-dependent manner. Mol Cell Biomech. 2007 Mar;4(1):13-25. (PIs: J.W. Triplett, NASA Graduate Student Researcher Program; F.M. Pavalko)
  6. Bailey SM, Cornforth MN. Telomeres and DNA double-strand breaks: Ever the twain shall meet? Cell Mol Life Sci. 2007 Sep 17; [Epub ahead of print] (PIs: S.M. Bailey, M.N. Cornforth)
  7. Andarawewa KL, Erickson AC, Chou WS, Costes SV, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff MH. Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor {beta}-induced epithelial to mesenchymal transition. Cancer Res. 2007 Sep 15;67(18):8662-70. (PI: M.H. Barcellos-Hoff)
  8. Zheng S, Liu M, Tai YC. Micro Coulter counters with platinum black electroplated electrodes for human blood cell sensing. Biomed Microdevices. 2007 Sep 18; [Epub ahead of print] (PI: Y.C. Tai)

Other papers of interest:

  1. Fischer DM, Arbeille P, Shoemaker JK, O'Leary DD, Hughson RL. Altered hormonal regulation and blood flow distribution with cardiovascular deconditioning after short-duration head down bed rest. J Appl Physiol. 2007 Sep 13; [Epub ahead of print]
  2. Yasuhara T, Hara K, Maki M, Matsukawa N, Fujino H, Date I, Borlongan CV. Lack of exercise, via hindlimb suspension, impedes endogenous neurogenesis. Neuroscience. 2007 Aug 9; [Epub ahead of print] Note: From summary of paper: "We have identified a novel paradigm, the HS model, for examining the role of withholding exercise in neurogenesis in the adult brain."
  3. Magnusson SP, Narici MV, Maganaris CN, Kjaer M. Human tendon behaviour and adaptation, in vivo. J Physiol. 2007 Sep 13; [Epub ahead of print]
  4. Takanokura M, Makabe H, Kaneko K, Mito K, Sakamoto K. Coordination of the upper-limb segments in physiological tremor with various external loads. Med Sci Monit. 2007 Sep;13(9):CR379-85. Note: This paper can be obtained online without charge.
  5. de Freitas PH, Kojima T, Ubaidus S, Li M, Shang G, Takagi R, Maeda T, Oda K, Ozawa H, Amizuka N. Histological assessments on the abnormalities of mouse epiphyseal chondrocytes with short term centrifugal loading. Biomed Res. 2007 Aug;28(4):191-203. Note: This paper can be obtained online without charge (large file).
  6. Dai ZQ, Wang R, Ling SK, Wan YM, Li YH. Simulated microgravity inhibits the proliferation and osteogenesis of rat bone marrow mesenchymal stem cells. Cell Prolif. 2007 Oct;40(5):671-84.
  7. O'Sullivan D. Exposure to galactic cosmic radiation and solar energetic particles. Radiat Prot Dosimetry. 2007 Sep 9; [Epub ahead of print]
  8. Sgouros G, Knox SJ, Joiner MC, Morgan WF, Kassis AI. MIRD Continuing Education: Bystander and low dose-rate effects: Are these relevant to radionuclide therapy? J Nucl Med. 2007 Sep 14; [Epub ahead of print]
  9. Natarajan M, Gibbons CF, Mohan S, Moore S, Kadhim MA. Oxidative stress signalling: A potential mediator of tumour necrosis factor alpha-induced genomic instability in primary vascular endothelial cells. Br J Radiol. 2007 Sep;80 Spec No 1:S13-22.
  10. Sun P, Huang Z, Cai DH, He L, Wu CX. [Effects of Chinese herbal medicine for supplementing Shen and strengthening the bone on rat distal femur cancellous bone in simulated weightlessness: An observation with scanning electron microscope.] Nan Fang Yi Ke Da Xue Xue Bao. 2007 Sep;27(9):1458-60. Chinese.
  11. Christopher DA, Borsics T, Yuen CY, Ullmer W, Andeme-Ondzighi C, Andres MA, Kang BH, Staehelin LA. The cyclic nucleotide gated cation channel AtCNGC10 traffics from the ER via Golgi vesicles to the plasma membrane of Arabidopsis root and leaf cells. BMC Plant Biol. 2007 Sep 19;7:48 [Epub ahead of print] Note: This paper can be obtained online without charge.

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