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NASA Spaceline 10 April 2009 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Thursday, May 28, 2009

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.



  1. Baqai FP, Gridley DS, Slater JM, Luo-Owen X, Stodieck LS, Ferguson VL, Chapes SK, Pecaut MJ. Effects of spaceflight on innate immune function and antioxidant gene expression. J Appl Physiol. 2009 Apr 2. [Epub ahead of print] (PI: S.K. Chapes) Note: STS-118 results. The overall flight experiment was sponsored by Amgen. From Discussion in paper: "We believe that several aspects of the spaceflight environment (e.g. microgravity, low-dose/low-dose-rate radiation, chronic psychological and physiological stress) lead to chronic, systemic increases in ROS. If kept unchecked, this would lead to chronic inflammatory disease."


  2. Lai N, Zhou H, Saidel GM, Wolf M, McCully K, Gladden LB, Cabrera ME. Modeling oxygenation in venous blood and skeletal muscle in response to exercise using near infrared spectroscopy. J Appl Physiol. 2009 Apr 2. [Epub ahead of print] (PI: M.E. Cabrera/G.M. Saidel)


  3. Buakhamsri A, Popovic ZB, Lin J, Lim P, Greenberg NL, Borowski AG, Wilson Tang WH, Klein AL, Lever HM, Desai MY, Thomas JD. Impact of left ventricular volume/mass ratio on diastolic function. Eur Heart J. 2009 Mar 20. [Epub ahead of print] (PI: J.D. Thomas)


  4. Damron FH, Napper J, Teter MA, Yu HD. Lipotoxin F of Pseudomonas aeruginosa is an AlgU-dependent and alginate-independent outer membrane protein involved in resistance to oxidative stress and adhesion to A549 human lung epithelia. Microbiology. 2009 Apr;155(Pt 4):1028-38. (PIs: F.H. Damron, NASA Graduate Student Researcher Program; H.D. Yu)


  5. Ganta RR, Peddireddi L, Seo GM, DeDonder SE, Cheng C, Chapes SK. Molecular characterization of Ehrlichia interactions with tick cells and macrophages. Front Biosci. 2009 Jan 1;14:3259-73. (PI: S.K. Chapes)




Other papers of interest:



  1. Brown SJ, Mundel T, Barnes M, Brown JA. Indirect measures of human vagal withdrawal during head-up tilt with and without a respiratory acidosis. J Physiol Sci. 2009 Jan;59(1):31-6. Epub 2008 Nov 30. Note: This article may be obtained online without charge.


  2. Kurushin VA, Ponomareva EV, Ogneva IV, Lipets EN, Shenkman BS. Quantitative evaluation of the relationship between Ca2+ sensitivity and sarcomere length in rat soleus after 14-day hindlimb suspension. Dokl Biol Sci. 2009 Jan-Feb;424(1):29-31. Note: This is an English translation of the Russian original published in Doklady Akademii Nauk 2009;424(6):832-5. The first page of the paper may be viewed without charge. Click to the issue and citation.


  3. Caron AZ, Drouin G, Desrosiers J, Trensz F, Grenier G. A novel hindlimb immobilization procedure for studying skeletal muscle atrophy and recovery in mouse. J Appl Physiol. 2009 Apr 2. [Epub ahead of print]


  4. Chiquet M, Gelman L, Lutz R, Maier S. From mechanotransduction to extracellular matrix gene expression in fibroblasts. Biochim Biophys Acta. 2009 Jan 30. [Epub ahead of print]


  5. Shimano MM, Volpon JB. Biomechanics and structural adaptations of the rat femur after hindlimb suspension and treadmill running. Braz J Med Biol Res. 2009 Apr;42(4):330-8. Note: This article may be obtained online without charge.


  6. Santos A, Bakker AD, Klein-Nulend J. The role of osteocytes in bone mechanotransduction. Osteoporos Int. 2009 Apr 2. [Epub ahead of print] Note: This article may be obtained online without charge.


  7. Kobayashi J, Tauchi H, Chen B, Bruma [Burma is correct] S, Tashiro S, Matsuura S, Tanimoto K, Chen DJ, Komatsu K. Histone H2AX participates the DNA damage-induced ATM activation through interaction with NBS1. Biochem Biophys Res Commun. 2009 Mar 20;380(4):752-7. Epub 2009 Jan 23.


  8. Hooper SL, Guschlbauer C, Bluemel M, Rosenbaum P, Gruhn M, Akay T, Bueschges A. Neural control of unloaded leg posture and of leg swing in stick insect, cockroach, and mouse differs from that in larger animals. J Neurosci. 2009 Apr 1;29(13):4109-19.


  9. Gorgiladze GI, Kozyrev SA, Nosovskii AM. Effect of enhanced gravity on the electrophysiological characteristics of statocyst sensory cells in Helix lucorum. Dokl Biol Sci. 2009 Jan-Feb;424(1):10-3. Note: This is an English translation of the Russian original published in Doklady Akademii Nauk 2009;424(3):415-8. The first page of the paper may be viewed without charge. Click to the issue and citation.


  10. Ikai A. A review on: Atomic force microscopy applied to nano-mechanics of the cell. Adv Biochem Eng Biotechnol. 2009 Mar 27. [Epub ahead of print]


  11. Huxley-Jones J, Pinney JW, Archer J, Robertson DL, Boot-Handford RP. Back to basics--how the evolution of the extracellular matrix underpinned vertebrate evolution. Int J Exp Pathol. 2009 Apr;90(2):95-100.


  12. Monshausen GB, Gilroy S. Feeling green: Mechanosensing in plants. Trends Cell Biol. 2009 Mar 31. [Epub ahead of print]


  13. Hu LW, Cui da Y, Zang AP, Neill S, Cai WM. Auxin-regulated OsRGP1 and OsSuS are involved in gravitropic bending of rice shoot bases. Fen Zi Xi Bao Sheng Wu Xue Bao. 2009 Feb;42(1):27-34.


  14. Li S, Ma Z, Niu Z, Qian H, Xuan D, Hou R, Ni L. NASA-approved rotary bioreactor enhances proliferation and osteogenesis of human periodontal ligament stem cells. Stem Cells Dev. 2009 Jan 26. [Epub ahead of print]







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