NASA Spaceline Current Awareness List #685 12 February 2016

Status Report From: Spaceline
Posted: Friday, February 12, 2016

Papers deriving from NASA support:



May PC, Bailey MR, Harper JD.

Ultrasonic propulsion of kidney stones.

Curr Opin Urol. 2016 Feb 3. [Epub ahead of print] Review.

PI: M.R. Bailey

Journal Impact Factor: 2.333

Funding: "Funding was provided by National Space Biomedical Research Institute (NSBRI) through NASA NCC 9-58, grants from the National Institute of Diabetes and Digestive and Kidney Diseases (DK043881 and DK092197), the UW Applied Physics Laboratory, the UW Department of Urology, CoMotion at the UW, The Wallace H. Coulter Foundation, and the UW Institute of Translational Health Sciences."



Cabahug-Zuckerman P, Frikha-Benayed D, Majeska RJ, Tuthill A, Yakar S, Judex S, Schaffler MB.

Osteocyte apoptosis caused by hindlimb unloading is required to trigger osteocyte RANKL production and subsequent resorption of cortical and trabecular bone in mice femurs.

J Bone Miner Res. 2016 Feb 6. [Epub ahead of print]

PI: S. Judex

Note: Hindlimb unloading study.

Journal Impact Factor: 6.832

Funding: "Research reported in this publication was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Awards Number AR041210, AR057139 and AR060445 (to MBS), and NASA grant NASA NNX08BA35G (to SJ)."



Clément G, Wood SJ.

Translational otolith-ocular reflex during off-vertical axis rotation in humans.

Neurosci Lett. 2016 Jan 28;616:65-9. [Epub ahead of print]

Journal Impact Factor: 2.030

Funding: "This study was supported by the National Aeronautics and Space Administration (NASA), the European Space Agency (ESA) and the Centre National d’Etudes Spatiales (CNES)." This is a joint ESA-NASA project; S.J. Wood is a Co-Investigator and is funded by the NASA HRP Human Health and Countermeasures program.



Park MR, Hasenstein KH.

Oxygen dependency of germinating Brassica seeds.

Life Sci Space Res. 2016 Feb 2. [Article in Press]

PI: K.H. Hasenstein

Journal Impact Factor: 1.183

Funding: "This research was supported by NASA grant NNX10AP91G."



Other papers of interest:



Gambelli CN, Theisen D, Willems PA, Schepens B.

Motor control of landing from a counter-movement jump in simulated microgravity.

J Appl Physiol (1985). 2016 Feb 4:jap.00993.2015. [Epub ahead of print]

Note: Parabolic flight results.



Wang D, Gao W, Tian Y, Wang C, Ge L, Chen S.

Influence of gravity on speed perception characteristics of human.

Space Med Med Eng (Beijing). 2015;2015(6):408-12. Chinese. 

Note: Parabolic flight and bed rest studies.



Aleshcheva G, Bauer J, Hemmersbach R, Slumstrup L, Wehland M, Infanger M, Grimm D.

Scaffold-free tissue formation under real and simulated microgravity conditions.

Basic Clin Pharmacol Toxicol. 2016 Jan 30. [Epub ahead of print] Review.

Note: Space flight results reviewed are from ISS, parabolic flight, and Shenzhou 8. Simulation methods are the 3D Random Positioning Machine, 2D Fast-Rotating Clinostat, and the Rotating Wall Vessel.



Feng J, Guo Z, Guo L, Ma Y, Wu D.

Progresses of researches on low back pain in astronauts.

Space Med Med Eng (Beijing). 2015;2015(6):456-9. Chinese.

Note: The specific spaceflight missions are not identified in the English abstract.



Shi F, Zhao TZ, Wang YC, Cao XS, Yang CB, Gao Y, Li CF, Zhao JD, Zhang S, Sun XQ.

The impact of simulated weightlessness on endothelium-dependent angiogenesis and the role of caveolae/caveolin-1.

Cell Physiol Biochem. 2016 Feb 1;38(2):502-13.

Note: A clinostat was used. This article may be obtained online without charge.



Wang FF, Fang YQ, You P, Bao XC, Ma J, Zhang S.

[Effect of different pressure oxygen pre-breathe in diving decompression sickness of rats].

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2015 Sep;31(5):401-4. Chinese.



Santos CA, Andrade LP, Costa MH, Souza HS, Granjeiro JM, Takiya CM, Borojevic R, Nasciutti LE.

Gastrospheres of human gastric mucosa cells: An in vitro model of stromal and epithelial stem cell niche reconstruction.

Histol Histopathol. 2016 Feb 2:11726. [Epub ahead of print]

Note: The NASA Rotating Cell Culture System was used. This article may be obtained online without charge.



Chen R, Wang Y, Shi F, Sun X.

Changes of autophagy activity in carotid and femoral arteries of tail suspension rats.

Space Med Med Eng (Beijing). 2015;2015(6):445-9. Chinese.

Note: Hindlimb unloading study.



Shimbo M, Kudo T, Hamada M, Jeon H, Imamura Y, Asano K, Okada R, Tsunakawa Y, Mizuno S, Yagami KI, Ishikawa C, Li H, Shiga T, Ishida J, Hamada J, Murata K, Ishimaru T, Hashimoto M, Fukamizu A, Yamane M, Ikawa M, Morita H, Shinohara M, Asahara H, Akiyama T, Akiyama N, Sasanuma H, Yoshida N, Zhou R, Wang YY, Ito T, Kokubu Y, Noguchi TK, Ishimine H, Kurisaki A, Shiba D, Mizuno H, Shirakawa M, Ito N, Takeda S, Takahashi S.

Ground-based assessment of JAXA mouse habitat cage unit by mouse phenotypic studies.

Exp Anim. 2016 Jan 28. [Epub ahead of print]

Note: A centrifuge was used. This article may be obtained online without charge.



Baehr LM, West DW, Marcotte G, Marshall AG, De Sousa LG, Baar K, Bodine SC.

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis.

Aging (Albany NY). 2016 Jan 29. [Epub ahead of print]

Note: Hindlimb unloading study.



Cotton CJ.

Skeletal muscle mass and composition during mammalian hibernation.

J Exp Biol. 2016 Jan;219(Pt 2):226-34. Review.

Note: This article may be obtained online without charge.



Mele A, Fonzino A, Rana F, Camerino GM, De Bellis M, Conte E, Giustino A, Conte Camerino D, Desaphy JF.

In vivo longitudinal study of rodent skeletal muscle atrophy using ultrasonography.

Sci Rep. 2016 Feb 1;6:20061.

Note: Hindlimb unloading study. This article may be obtained online without charge.



Pišot R, Marusic U, Biolo G, Mazzucco S, Lazzer S, Grassi B, Reggiani C, Toniolo L, di Prampero PE, Passaro A, Narici MV, Mohammed S, Rittweger J, Gasparini M, Gabrijelčič M, Šimunič B.

Greater loss in muscle mass and function but smaller metabolic alterations in older compared to younger men following two weeks of bed rest and recovery.

J Appl Physiol (1985). 2016 Jan 28:jap.00858.2015. [Epub ahead of print]

Note: Bed rest study.



Tesch PA, Lundberg TR, Fernandez Gonzalo R.

Unilateral lower limb suspension (ULLS): From subject selection to "omic" responses.

J Appl Physiol (1985). 2016 Feb 4:jap.01052.2015. Review. [Epub ahead of print]

Note: The effects of unilateral lower limb suspension on muscle are reviewed.



Zhang ZK, Li J, Liu J, Guo B, Leung A, Zhang G, Zhang BT.

Icaritin requires phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading.

Sci Rep. 2016;6:20300.

Note: Hindlimb unloading study. This article may be obtained online without charge.



Anderson MJ, Diko S, Baehr LM, Baar K, Bodine SC, Christiansen BA.

Contribution of mechanical unloading to trabecular bone loss following non-invasive knee injury in mice.

J Orthop Res. 2016 Jan 30. [Epub ahead of print]

Note: Hindlimb unloading study.



Liu J, Song S, Si S, Guo Y.

Inhibitory effect of oral administration of strontium ranelate and bovine collagen peptide on bone loss in tail suspended rats.

Space Med Med Eng (Beijing). 2015;2015(6):432-6.

Note: Hindlimb unloading study.



Paiva AG, Yanagihara GR, Macedo AP, Ramos J, Issa JP, Shimano AC.

Analysis of fracture healing in osteopenic bone caused by disuse: Experimental study.

Braz J Med Biol Res. 2016 Mar;49(3). Epub 2016 Feb 2.

Note: Hindlimb unloading study. This article may be obtained online without charge



Yanagihara GR, Paiva AG, Gasparini GA, Macedo AP, Frighetto PD, Volpon JB, Shimano AC.

High-impact exercise in rats prior to and during suspension can prevent bone loss.

Braz J Med Biol Res. 2016 Mar;49(3). Epub 2016 Feb 2.

Note: Hindlimb unloading study. This article may be obtained online without charge.



Matsuura Y, Takada H.

Evaluation of motion sickness induced by 3D video clips.

Nihon Eiseigaku Zasshi. 2016;71(1):2-11. Japanese.

Note: This article may be obtained online without charge.



Voigt RM, Summa KC, Forsyth CB, Green SJ, Engen P, Naqib A, Vitaterna MH, Turek FW, Keshavarzian A.

The circadian Clock mutation promotes intestinal dysbiosis.

Alcohol Clin Exp Res. 2016 Feb;40(2):335-47.



Marusich LR, Bakdash JZ, Onal E, Yu MS, Schaffer J, O'Donovan J, Höllerer T, Buchler N, Gonzalez C.

Effects of information availability on command-and-control decision making: Performance, trust, and situation awareness.

Hum Factors. 2016 Jan 28. [Epub ahead of print]

Note: This article may be obtained online without charge.



Liang X, Fu Y, Liu H.

Research progress on candidate animal protein—Silkworm in bioregenerative life support system.

Space Med Med Eng (Beijing). 2015;2015(6):460-3. Chinese.



Cummins BM, Ligler FS, Walker GM.

Point-of-care diagnostics for niche applications.

Biotechnol Adv. 2016 Jan 30. [Epub ahead of print]

Note: The special applications discussed are veterinary medicine, space travel, sports medicine, emergency medicine, and operating room efficiency.



Song J, Yan H, Xu Z, Li F, Yu X.

Textile electrode technologies applicable to on-orbit electrocardiogram acquisition of astronauts.

Space Med Med Eng (Beijing). 2015;2015(6):464-8.




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